Biotechnology Sequence Checker

Check a Sequence Listing in Computer Readable Form (CRF) for compliance with WIPO standards before submission to the USPTO.

Checker Version 4.4.6

Checker Version 4.4.6 is a Microsoft Windows-based software application for checking biotechnology Sequence Listings for compliance with format and content rules. Checker Version 4.4.6 validates sequence listings generated in accordance with the US sequence rules, 37 CFR §§1.821 - 1.825, effective July 1, 1998, the World Intellectual Property Organization (WIPO) Standard ST.25, as well as Sequence Listings created with the "old rules", those which became effective October 1, 1990.

Checker Version 4.4.6 replaces all previous versions. Checker allows public users to check Sequence Listings in Computer Readable Form (CRF) before submitting them to the United States Patent and Trademark Office (USPTO). Use of Checker prior to filing Sequence Listings has resulted in fewer Sequence Listing errors discovered by USPTO, therefore fewer Sequence Listings returned to Applicants for correction. Checker 4.4.6 features full compatibility with the Microsoft Windows XP, Vista, and 7 operating systems as well as all Office 2000/XP products. Also, a setup file named, Checker.msi , assures fast and easy installation of the application.

Please Note: Should an installation path other than the default be specified, the initial execution of Checker will require modifications to the input and output folder paths. The user will be alerted to this and then presented with the Checker Properties Dialog (see User's Manual Section 3.2.6).


Download Checker Version 4.4.6 Software (file size 1.33 MB)


Where to Call for Help

For help related to downloading the application or using Checker 4.4.6, or to report problems encountered running the program call toll-free to the Patent Electronic Business Center at 866-217-9197 or contact them via Email at