Software tools are publicly available for creating and editing sequence listings in both WIPO ST.25 and ST.26 formats.
Applications with a filing date or international filing date on or before June 30, 2022, must comply with ST.25 text file format. Use PatentIn and Checker to generate and validate an ST.25 format sequence listing.
Applications with a filing date or international filing date on or after July 1, 2022, must comply with ST.26 XML format. Use WIPO Sequence to generate and validate an ST.26 format sequence listing.
PatentIn for ST.25 sequence listings
PatentIn is a free software program designed to assist an applicant in preparing sequence listings in ST.25 format. Download PatentIn 3.5.1 and the user manual.
Checker for ST.25 sequence listings
Checker is a free software program that allows applicants to validate a sequence listing text file in ST.25 format against a subset of the sequence rules. Download 4.4.6 and the user manual.
WIPO Sequence for ST.26 sequence listings
WIPO Sequence is a free software program designed to assist an applicant in preparing sequence listings in ST.26 format. Download WIPO Sequence version 2.3.0 and the User Manual.
Important note: Sequence listings created with older versions of WIPO Sequence may not be compliant with Standard ST.26. These sequence listings should be regenerated using WIPO Sequence 2.3.0 before filing as part of a U.S. or international patent application. The functionality and updates of WIPO Sequence fall under the sole responsibility of WIPO, not the USPTO.