1. CPC Sections
  2. CPC Section C
  3. CPC Class C12
  4. CPC Subclass C12Q
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CPC
COOPERATIVE PATENT CLASSIFICATION
​​
C12Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS (immunoassay G01N 33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES [2022-05]
NOTES

  • This subclass does not cover the observation of the progress or of the result of processes specified in this subclass by any of the methods specified in groups G01N 3/00 - G01N 29/00, which is covered by subclass G01N.
  • In this subclass, the following expression is used with the meaning indicated:
    • "involving", when used in relation to a substance, includes the testing for the substance as well as employing the substance as a determinant or reactant in a test for a different substance.
  • Attention is drawn to Notes (1) to (3) following the title of class C12.
  • In this subclass, test media are classified in the appropriate group for the relevant test process.
  • In this subclass, it is desirable to add the indexing codes of subclass C12R.
  • {Documents describing the use of an electrode for analysis of a specific analyte are classified in C12Q 1/001 or subgroups and not according to the last place rule.}
  • {Documents relating to new peptides, e.g. enzymes, or new DNA or its corresponding mRNA, encoding for the peptides, and their use in measuring or testing processes are classified in subclass C07K or in group C12N 9/00 according to the peptides, with the appropriate indexing codes relating to their use in diagnostics. However, where the new nucleic acids are principally used in diagnostic processes, e.g. PCR, hybridisation reactions, the documents are also classified in group C12Q 1/68.}
  • {In groups C12Q 1/6876 - C12Q 1/6895 and C12Q 1/701 - C12Q 1/708 it is compulsory to add the indexing codes C12Q 2600/00 - C12Q 2600/178 which reflect the use of the product in combination with the virus groups only if the document relates to products.}
  • {In this subclass, combination sets [C-Sets] are used. The detailed information about the C-Sets construction and the associated syntax rules is present in the definitions of C12Q.}
WARNING

  • In this subclass non-limiting references (in the sense of paragraph 39 of the Guide to the IPC) may still be displayed in the scheme.
​
C12Q 1/00
Measuring or testing processes involving enzymes, nucleic acids or microorganisms (measuring or testing apparatus with condition measuring or sensing means, e.g. colony counters, C12M 1/34); Compositions therefor; Processes of preparing such compositions [2022-05]
NOTE

  • {In this group, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12Q.}
C12Q 1/001
.
{Enzyme electrodes} [2013-01]
C12Q 1/002
. .
{Electrode membranes} [2013-01]
C12Q 1/003
. . .
{Functionalisation} [2013-01]
C12Q 1/004
. .
{mediator-assisted} [2013-01]
C12Q 1/005
. .
{involving specific analytes or enzymes (including groups of enzymes, e.g. oxydases; C12Q 1/004 takes precedence)} [2013-01]
C12Q 1/006
. . .
{for glucose} [2013-01]
C12Q 1/007
.
{involving isoenzyme profiles (for detection of an individual isoenzyme C12Q 1/25 - C12Q 1/66)} [2016-05]
C12Q 1/008
.
{for determining co-enzymes or co-factors, e.g. NAD, ATP} [2013-01]
C12Q 1/02
.
involving viable microorganisms [2017-08]
C12Q 1/025
. .
{for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics (antimicrobial activity C12Q 1/18)} [2013-01]
C12Q 1/04
. .
Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor {(C12Q 1/6897 takes precedence)} [2017-08]
C12Q 1/045
. . .
{Culture media therefor} [2013-01]
C12Q 1/06
. . .
Quantitative determination [2013-01]
C12Q 1/08
. . . .
using multifield media [2013-01]
C12Q 1/10
. . .
Enterobacteria [2013-01]
C12Q 1/12
. . .
Nitrate to nitrite reducing bacteria [2013-01]
C12Q 1/14
. . .
Streptococcus; Staphylococcus [2013-01]
C12Q 1/16
. . .
using radioactive material [2013-01]
C12Q 1/18
. .
Testing for antimicrobial activity of a material [2013-01]
C12Q 1/20
. . .
using multifield media [2013-01]
C12Q 1/22
. .
Testing for sterility conditions [2013-01]
C12Q 1/24
. .
Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms [2017-08]
C12Q 1/25
.
involving enzymes not classifiable in groups C12Q 1/26 {- C12Q 1/66} [2016-05]
C12Q 1/26
.
involving oxidoreductase [2013-01]
C12Q 1/28
. .
involving peroxidase [2013-01]
C12Q 1/30
. .
involving catalase [2013-01]
C12Q 1/32
. .
involving dehydrogenase [2013-01]
C12Q 1/34
.
involving hydrolase [2013-01]
C12Q 1/37
. .
involving peptidase or proteinase [2013-01]
C12Q 1/40
. .
involving amylase [2013-01]
C12Q 1/42
. .
involving phosphatase [2013-01]
C12Q 1/44
. .
involving esterase [2013-01]
C12Q 1/46
. . .
involving cholinesterase [2013-01]
C12Q 1/48
.
involving transferase [2013-01]
C12Q 1/485
. .
{involving kinase} [2013-01]
C12Q 1/50
. .
involving creatine phosphokinase [2013-01]
C12Q 1/52
. .
involving transaminase [2013-01]
C12Q 1/527
.
involving lyase [2013-01]
C12Q 1/533
.
involving isomerase [2013-01]
C12Q 1/54
.
involving glucose or galactose [2013-01]
C12Q 1/56
.
involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen [2013-01]
C12Q 1/58
.
involving urea or urease [2013-01]
C12Q 1/60
.
involving cholesterol [2013-01]
C12Q 1/61
.
involving triglycerides [2013-01]
C12Q 1/62
.
involving uric acid [2013-01]
C12Q 1/64
.
Geomicrobiological testing, e.g. for petroleum [2013-01]
C12Q 1/66
.
involving luciferase [2013-01]
​
C12Q 1/68
.
involving nucleic acids [2022-05]
NOTES

  • In this group, classification is made according to the most relevant feature irrespective of the last place priority rule.
  • {In groups C12Q 1/68 - C12Q 1/6874, and C12Q 1/6897, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12Q.}
C12Q 1/6804
. .
Nucleic acid analysis using immunogens (immunoassay G01N 33/53) [2018-05]
C12Q 1/6806
. .
Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay (C12Q 1/6804 takes precedence) [2018-05]
C12Q 1/6809
. .
Methods for determination or identification of nucleic acids involving differential detection [2018-05]
C12Q 1/6811
. .
Selection methods for production or design of target specific oligonucleotides or binding molecules [2018-05]
C12Q 1/6813
. .
Hybridisation assays [2018-05]
C12Q 1/6816
. . .
characterised by the detection means (C12Q 1/6804 takes precedence) [2018-05]
C12Q 1/6818
. . . .
involving interaction of two or more labels, e.g. resonant energy transfer [2018-05]
C12Q 1/682
. . . .
Signal amplification [2018-05]
C12Q 1/6823
. . . .
Release of bound markers [2018-05]
C12Q 1/6825
. . . .
Nucleic acid detection involving sensors [2018-05]
C12Q 1/6827
. . .
for detection of mutation or polymorphism [2018-05]
C12Q 1/683
. . . .
involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP] [2018-05]
C12Q 1/6832
. . .
Enhancement of hybridisation reaction [2018-05]
C12Q 1/6834
. . .
Enzymatic or biochemical coupling of nucleic acids to a solid phase [2018-05]
C12Q 1/6837
. . . .
using probe arrays or probe chips (C12Q 1/6874 takes precedence) [2018-05]
C12Q 1/6839
. . .
Triple helix formation or other higher order conformations in hybridisation assays [2018-05]
C12Q 1/6841
. . .
In situ hybridisation [2018-05]
C12Q 1/6844
. .
Nucleic acid amplification reactions [2018-05]
C12Q 1/6846
. . .
{Common amplification features} [2018-05]
C12Q 1/6848
. . .
characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction [2018-05]
C12Q 1/6851
. . .
Quantitative amplification [2018-05]
C12Q 1/6853
. . .
using modified primers or templates [2018-05]
C12Q 1/6855
. . . .
Ligating adaptors [2018-05]
C12Q 1/6858
. . .
Allele-specific amplification [2018-05]
C12Q 1/686
. . .
Polymerase chain reaction [PCR] [2018-05]
C12Q 1/6862
. . .
Ligase chain reaction [LCR] [2018-05]
C12Q 1/6865
. . .
Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS] [2018-05]
C12Q 1/6867
. . .
Replicase-based amplification, e.g. using Q-beta replicase [2018-05]
C12Q 1/6869
. .
Methods for sequencing [2018-05]
C12Q 1/6872
. . .
involving mass spectrometry [2018-05]
C12Q 1/6874
. . .
involving nucleic acid arrays, e.g. sequencing by hybridisation [2018-05]
C12Q 1/6876
. .
Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes [2018-05]
C12Q 1/6879
. . .
for sex determination [2018-05]
C12Q 1/6881
. . .
for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes [2018-05]
C12Q 1/6883
. . .
for diseases caused by alterations of genetic material [2018-05]
C12Q 1/6886
. . . .
for cancer (immunoassay for cancer G01N 33/574) [2018-05]
C12Q 1/6888
. . .
for detection or identification of organisms [2018-05]
C12Q 1/689
. . . .
for bacteria [2018-05]
C12Q 1/6893
. . . .
for protozoa [2018-05]
C12Q 1/6895
. . . .
for plants, fungi or algae [2018-05]
C12Q 1/6897
. .
involving reporter genes operably linked to promoters [2018-05]
​
C12Q 1/70
.
involving virus or bacteriophage {(immunoassay for viruses G01N 33/56983)} [2022-05]
NOTES

  • {In this group, classification is made according to the most relevant feature irrespective of the last place priority rule.}
  • {In this group, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12Q.}
C12Q 1/701
. .
{Specific hybridization probes} [2013-01]
C12Q 1/702
. . .
{for retroviruses} [2013-01]
C12Q 1/703
. . . .
{Viruses associated with AIDS} [2013-01]
C12Q 1/705
. . .
{for herpetoviridae, e.g. herpes simplex, varicella zoster} [2013-01]
C12Q 1/706
. . .
{for hepatitis} [2013-01]
C12Q 1/707
. . . .
{non-A, non-B Hepatitis, excluding hepatitis D} [2013-01]
C12Q 1/708
. . .
{for papilloma} [2013-01]
C12Q 3/00
Condition responsive control processes (apparatus therefor C12M 1/36; controlling or regulating in general G05) [2013-01]
C12Q 2304/00
Chemical means of detecting microorganisms [2024-08]
C12Q 2304/10
.
DNA staining [2013-01]
C12Q 2304/12
. .
Ethidium [2013-01]
C12Q 2304/13
. .
Propidium [2013-01]
C12Q 2304/16
. .
Acridine orange [2013-01]
C12Q 2304/18
. .
Thionin-type dyes, e.g. Azure, Toluidine Blue [2013-01]
C12Q 2304/20
.
Redox indicators [2013-01]
C12Q 2304/22
. .
Resazurin; Resorufin [2013-01]
C12Q 2304/24
. .
Tetrazolium; Formazan [2013-01]
C12Q 2304/26
. .
Quinone; Quinol [2013-01]
C12Q 2304/40
.
Detection of gases [2013-01]
C12Q 2304/44
. .
Oxygen [2013-01]
C12Q 2304/46
. .
Carbon dioxide [2013-01]
C12Q 2304/48
. .
Ammonia or volatile amines [2013-01]
C12Q 2304/60
.
Chemiluminescent detection using ATP-luciferin-luciferase system [2013-01]
C12Q 2304/80
.
Electrochemical detection via electrodes in contact with culture medium [2013-01]
C12Q 2326/00
Chromogens for determinations of oxidoreductase enzymes [2013-01]
C12Q 2326/10
.
Benzidines [2013-01]
C12Q 2326/12
. .
3,3',5,5'-Tetramethylbenzidine, i.e. TMB [2013-01]
C12Q 2326/14
. .
Ortho-Tolidine, i.e. 3,3'-dimethyl-(1,1'-biphenyl-4,4'-diamine) [2013-01]
C12Q 2326/20
.
Ortho-Phenylenediamine [2013-01]
C12Q 2326/30
.
2,2'-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid), i.e. ABTS [2013-01]
C12Q 2326/32
.
3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate, i.e. MBTH [2013-01]
C12Q 2326/40
.
Triphenylmethane dye chromogens, e.g. fluorescein derivatives [2013-01]
C12Q 2326/50
.
Phenols; Naphthols; Catechols [2013-01]
C12Q 2326/90
.
Developer [2013-01]
C12Q 2326/92
. .
Nitro blue tetrazolium chloride, i.e. NBT [2013-01]
C12Q 2326/96
. .
4-Amino-antipyrine [2013-01]
C12Q 2334/00
O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases [2013-01]
C12Q 2334/10
.
p-Nitrophenol derivatives [2013-01]
C12Q 2334/20
.
Coumarin derivatives [2013-01]
C12Q 2334/22
. .
4-Methylumbelliferyl, i.e. beta-methylumbelliferone, 4MU [2013-01]
C12Q 2334/30
.
Naphthol derivatives, e.g. alpha-naphthyl-esters, i.e. alpha-NE, beta-naphthyl-esters, i.e. beta-NE [2013-01]
C12Q 2334/40
.
Triphenylmethane dye chromogens, e.g. fluorescein derivatives [2013-01]
C12Q 2334/50
.
Indoles [2013-01]
C12Q 2334/52
. .
5-Bromo-4-chloro-3-indolyl, i.e. BCI [2013-01]
C12Q 2334/70
.
the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red [2013-01]
C12Q 2337/00
N-linked chromogens for determinations of peptidases and proteinases [2013-01]
C12Q 2337/10
.
Anilides [2013-01]
C12Q 2337/12
. .
Para-Nitroanilides p-NA [2013-01]
C12Q 2337/20
.
Coumarin derivatives [2013-01]
C12Q 2337/22
. .
7-Amino-4-methylcoumarin, i.e. AMC, MCA [2013-01]
C12Q 2337/24
. .
7-Amino-4-trifluoromethylcoumarin, i.e. AFC [2013-01]
C12Q 2337/30
.
Naphthyl amides, e.g. beta-NA, 2-NA, 4-methoxy-beta-naphthylamine, i.e. 4MNA [2013-01]
C12Q 2337/40
.
Rhodamine derivatives [2013-01]
C12Q 2337/50
.
Indoles [2013-01]
C12Q 2337/52
. .
5-Bromo-4-chloro-3-indolyl, i.e. BCI [2013-01]
​
C12Q 2500/00
Analytical methods involving nucleic acids [2022-05]
NOTE

  • Indexing codes C12Q 2500/00 - C12Q 2565/634 are only used as subsequent symbols in C-Sets and are not allocated as single symbols. The detailed information about the C-Sets construction and the associated syntax rules is present in the Definitions of C12Q.
C12Q 2520/00
Reactions involving nucleic acids [2019-08]
C12Q 2521/00
Reaction characterised by the enzymatic activity [2019-08]
C12Q 2521/10
.
Nucleotidyl transfering [2019-08]
C12Q 2521/101
. .
DNA polymerase [2013-01]
C12Q 2521/107
. .
RNA dependent DNA polymerase,(i.e. reverse transcriptase) [2013-01]
C12Q 2521/113
. .
Telomerase [2013-01]
C12Q 2521/119
. .
RNA polymerase [2013-01]
C12Q 2521/125
. .
Methyl transferase, i.e. methylase [2013-01]
C12Q 2521/131
. .
Terminal transferase [2013-01]
C12Q 2521/30
.
Phosphoric diester hydrolysing, i.e. nuclease [2019-08]
C12Q 2521/301
. .
Endonuclease [2013-01]
C12Q 2521/307
. .
Single strand endonuclease [2013-01]
C12Q 2521/313
. .
Type II endonucleases, i.e. cutting outside recognition site [2013-01]
C12Q 2521/319
. .
Exonuclease [2013-01]
C12Q 2521/325
. .
Single stranded exonuclease [2013-01]
C12Q 2521/327
. .
RNAse, e.g. RNAseH [2013-01]
C12Q 2521/331
. .
Methylation site specific nuclease [2013-01]
C12Q 2521/337
. .
Ribozyme [2013-01]
C12Q 2521/343
. .
Abzyme [2013-01]
C12Q 2521/345
. .
DNAzyme [2013-01]
C12Q 2521/50
.
Other enzymatic activities [2019-08]
C12Q 2521/501
. .
Ligase [2013-01]
C12Q 2521/507
. .
Recombinase [2013-01]
C12Q 2521/513
. .
Winding/unwinding enzyme, e.g. helicase [2013-01]
C12Q 2521/514
. .
Mismatch repair protein [2013-01]
C12Q 2521/519
. .
Topoisomerase [2013-01]
C12Q 2521/525
. .
Phosphatase [2019-08]
C12Q 2521/531
. .
Glycosylase [2013-01]
C12Q 2521/537
. .
Protease [2013-01]
C12Q 2521/539
. .
Deaminase [2013-01]
C12Q 2521/543
. .
Immobilised enzyme(s) [2013-01]
C12Q 2522/00
Reaction characterised by the use of non-enzymatic proteins [2019-08]
C12Q 2522/10
.
Nucleic acid binding proteins [2019-08]
C12Q 2522/101
. .
Single or double stranded nucleic acid binding proteins [2013-01]
C12Q 2523/00
Reactions characterised by treatment of reaction samples [2019-08]
C12Q 2523/10
.
Characterised by chemical treatment [2019-08]
C12Q 2523/101
. .
Crosslinking agents, e.g. psoralen [2013-01]
C12Q 2523/107
. .
Chemical cleaving agents [2013-01]
C12Q 2523/109
. .
chemical ligation between nucleic acids [2013-01]
C12Q 2523/113
. .
Denaturating agents [2013-01]
C12Q 2523/115
. .
oxidising agents [2013-01]
C12Q 2523/119
. .
Renaturing agents [2013-01]
C12Q 2523/125
. .
Bisulfite(s) [2013-01]
C12Q 2523/30
.
Characterised by physical treatment [2019-08]
C12Q 2523/301
. .
Sonication [2013-01]
C12Q 2523/303
. .
Applying a physical force on a nucleic acid [2013-01]
C12Q 2523/305
. .
Denaturation or renaturation by physical action [2013-01]
C12Q 2523/307
. .
Denaturation or renaturation by electric current/voltage [2013-01]
C12Q 2523/308
. .
Adsorption or desorption [2013-01]
C12Q 2523/31
. .
Electrostatic interactions, e.g. use of cationic polymers in hybridisation reactions [2013-01]
C12Q 2523/313
. .
Irradiation, e.g. UV irradiation [2013-01]
C12Q 2523/319
. .
Photocleavage, photolysis, photoactivation [2013-01]
C12Q 2523/32
. .
Centrifugation [2013-01]
C12Q 2525/00
Reactions involving modified oligonucleotides, nucleic acids, or nucleotides [2013-01]
C12Q 2525/10
.
Modifications characterised by [2013-01]
C12Q 2525/101
. .
incorporating non-naturally occurring nucleotides, e.g. inosine [2013-01]
C12Q 2525/107
. .
incorporating a peptide nucleic acid [2013-01]
C12Q 2525/113
. .
incorporating modified backbone [2013-01]
C12Q 2525/117
. .
incorporating modified base [2013-01]
C12Q 2525/119
. .
incorporating abasic sites [2013-01]
C12Q 2525/121
. .
incorporating both deoxyribonucleotides and ribonucleotides [2013-01]
C12Q 2525/125
. .
incorporating agents resulting in resistance to degradation [2013-01]
C12Q 2525/131
. .
incorporating a restriction site [2013-01]
C12Q 2525/137
. .
incorporating/modifying moieties to eliminate restriction sites [2013-01]
C12Q 2525/143
. .
incorporating a promoter sequence [2019-08]
C12Q 2525/149
. .
incorporating a coding sequence [2013-01]
C12Q 2525/15
. .
incorporating a consensus or conserved sequence [2013-01]
C12Q 2525/151
. .
repeat or repeated sequences, e.g. VNTR, microsatellite, concatemer [2013-01]
C12Q 2525/155
. .
incorporating/generating a new priming site [2013-01]
C12Q 2525/161
. .
incorporating target specific and non-target specific sites [2013-01]
C12Q 2525/173
. .
incorporating a polynucleotide run, e.g. polyAs, polyTs [2013-01]
C12Q 2525/179
. .
incorporating arbitrary or random nucleotide sequences [2013-01]
C12Q 2525/185
. .
incorporating bases where the precise position of the bases in the nucleic acid string is important [2019-08]
C12Q 2525/186
. .
incorporating a non-extendable or blocking moiety [2019-08]
C12Q 2525/191
. .
incorporating an adaptor [2013-01]
C12Q 2525/197
. .
incorporating a spacer/coupling moiety [2013-01]
C12Q 2525/203
. .
incorporating a composite nucleic acid containing a polypeptide sequence other than PNA [2013-01]
C12Q 2525/204
. .
specific length of the oligonucleotides [2013-01]
C12Q 2525/205
. .
Aptamer [2013-01]
C12Q 2525/207
. .
siRNA, miRNA [2013-01]
C12Q 2525/30
.
Oligonucleotides characterised by their secondary structure [2013-01]
C12Q 2525/301
. .
Hairpin oligonucleotides [2013-01]
C12Q 2525/307
. .
Circular oligonucleotides [2013-01]
C12Q 2525/313
. .
Branched oligonucleotides [2013-01]
C12Q 2527/00
Reactions demanding special reaction conditions [2019-08]
C12Q 2527/101
.
Temperature [2019-08]
C12Q 2527/107
.
Temperature of melting, i.e. Tm [2019-08]
C12Q 2527/109
.
Pressure [2019-08]
C12Q 2527/113
.
Time [2019-08]
C12Q 2527/119
.
pH [2019-08]
C12Q 2527/125
.
Specific component of sample, medium or buffer [2019-08]
C12Q 2527/127
.
the enzyme inhibitor or activator used [2019-08]
C12Q 2527/137
.
Concentration of a component of medium [2019-08]
C12Q 2527/143
.
Concentration of primer or probe [2019-08]
C12Q 2527/146
.
Concentration of target or template [2019-08]
C12Q 2527/149
.
Concentration of an enzyme [2019-08]
C12Q 2527/15
.
Gradients [2019-08]
C12Q 2527/153
.
Viscosity [2019-08]
C12Q 2527/156
.
Permeability [2019-08]
C12Q 2531/00
Reactions of nucleic acids characterised by [2013-01]
C12Q 2531/10
.
the purpose being amplify/increase the copy number of target nucleic acid [2019-08]
C12Q 2531/101
. .
Linear amplification, i.e. non exponential [2013-01]
C12Q 2531/107
. .
Probe or oligonucleotide ligation [2019-08]
C12Q 2531/113
. .
PCR [2013-01]
C12Q 2531/119
. .
Strand displacement amplification [SDA] [2013-01]
C12Q 2531/125
. .
Rolling circle [2013-01]
C12Q 2531/131
. .
Inverse PCR [2013-01]
C12Q 2531/137
. .
Ligase Chain Reaction [LCR] [2013-01]
C12Q 2531/143
. .
Promoter based amplification, e.g. NASBA, 3SR, TAS [2013-01]
C12Q 2531/149
. .
Replicase based amplification, e.g. Q beta replicase [2013-01]
C12Q 2533/00
Reactions characterised by the enzymatic reaction principle used [2018-01]
C12Q 2533/10
.
the purpose being to increase the length of an oligonucleotide strand [2019-08]
C12Q 2533/101
. .
Primer extension [2019-08]
C12Q 2533/107
. .
Probe or oligonucleotide ligation [2019-08]
C12Q 2535/00
Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides [2019-08]
C12Q 2535/101
.
Sanger sequencing method, i.e. oligonucleotide sequencing using primer elongation and dideoxynucleotides as chain terminators [2019-08]
C12Q 2535/107
.
Maxam and Gilbert method, i.e. sequential release and detection of nucleotides [2019-08]
C12Q 2535/113
.
Cycle sequencing [2019-08]
C12Q 2535/119
.
Double strand sequencing [2019-08]
C12Q 2535/122
.
Massive parallel sequencing [2019-08]
C12Q 2535/125
.
Allele specific primer extension [2019-08]
C12Q 2535/131
.
Allele specific probes [2019-08]
C12Q 2535/137
.
Amplification Refractory Mutation System [ARMS] [2019-08]
C12Q 2535/138
.
Amplified fragment length polymorphism [AFLP] [2019-08]
C12Q 2535/139
.
Random amplification polymorphism detection [RAPD] [2019-08]
C12Q 2537/00
Reactions characterised by the reaction format or use of a specific feature [2018-01]
C12Q 2537/10
.
the purpose or use of [2013-01]
C12Q 2537/101
. .
Homogeneous assay format, e.g. one pot reaction [2013-01]
C12Q 2537/107
. .
Homoduplex formation [2013-01]
C12Q 2537/113
. .
Heteroduplex formation [2013-01]
C12Q 2537/119
. .
Triple helix formation [2013-01]
C12Q 2537/125
. .
Sandwich assay format [2013-01]
C12Q 2537/137
. .
a displacement step [2019-08]
C12Q 2537/1373
. . .
Displacement by a nucleic acid [2013-01]
C12Q 2537/1376
. . .
Displacement by an enzyme [2013-01]
C12Q 2537/143
. .
Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis [2013-01]
C12Q 2537/149
. .
Sequential reactions [2019-08]
C12Q 2537/155
. .
Cyclic reactions [2019-08]
C12Q 2537/157
. .
A reaction step characterised by the number of molecules incorporated or released [2013-01]
C12Q 2537/159
. .
Reduction of complexity, e.g. amplification of subsets, removing duplicated genomic regions [2013-01]
C12Q 2537/16
. .
Assays for determining copy number or wherein the copy number is of special importance [2013-01]
C12Q 2537/161
. .
A competitive reaction step [2019-08]
C12Q 2537/162
. .
Helper probe [2013-01]
C12Q 2537/163
. .
blocking probe [2019-08]
C12Q 2537/164
. .
Methylation detection other then bisulfite or methylation sensitive restriction endonucleases [2013-01]
C12Q 2537/165
. .
Mathematical modelling, e.g. logarithm, ratio [2013-01]
C12Q 2539/00
Reactions characterised by analysis of gene expression or genome comparison [2018-01]
C12Q 2539/10
.
The purpose being sequence identification by analysis of gene expression or genome comparison characterised by [2013-01]
C12Q 2539/101
. .
Subtraction analysis [2013-01]
C12Q 2539/103
. .
Serial analysis of gene expression [SAGE] [2013-01]
C12Q 2539/105
. .
Involving introns, exons, or splice junctions [2013-01]
C12Q 2539/107
. .
Representational Difference Analysis [RDA] [2013-01]
C12Q 2539/113
. .
Differential Display Analysis [DDA] [2013-01]
C12Q 2539/115
. .
Comparative genomic hybridisation [CGH] [2013-01]
C12Q 2541/00
Reactions characterised by directed evolution [2018-01]
C12Q 2541/10
.
the purpose being the selection or design of target specific nucleic acid binding sequences [2019-08]
C12Q 2541/101
. .
Selex [2013-01]
C12Q 2543/00
Reactions characterised by the reaction site, e.g. cell or chromosome [2018-01]
C12Q 2543/10
.
the purpose being "in situ" analysis [2013-01]
C12Q 2543/101
. .
in situ amplification [2013-01]
C12Q 2545/00
Reactions characterised by their quantitative nature [2018-01]
C12Q 2545/10
.
the purpose being quantitative analysis [2019-08]
C12Q 2545/101
. .
with an internal standard/control [2013-01]
C12Q 2545/107
. .
with a competitive internal standard/control [2013-01]
C12Q 2545/113
. .
with an external standard/control, i.e. control reaction is separated from the test/target reaction [2013-01]
C12Q 2545/114
. .
involving a quantitation step [2019-08]
C12Q 2547/00
Reactions characterised by the features used to prevent contamination [2018-01]
C12Q 2547/10
.
the purpose being preventing contamination [2019-08]
C12Q 2547/101
. .
by confinement to a single tube/container [2013-01]
C12Q 2547/107
. .
Use of permeable barriers, e.g. waxes [2013-01]
C12Q 2549/00
Reactions characterised by the features used to influence the efficiency or specificity [2018-01]
C12Q 2549/10
.
the purpose being that of reducing false positive or false negative signals [2019-08]
C12Q 2549/101
. .
Hot start [2013-01]
C12Q 2549/107
. .
Cold start [2013-01]
C12Q 2549/113
. .
using nested probes [2013-01]
C12Q 2549/119
. .
using nested primers [2013-01]
C12Q 2549/125
. .
using sterilising/blocking agents, e.g. albumin [2013-01]
C12Q 2549/126
. .
using oligonucleotides as clamps [2019-08]
C12Q 2560/00
Nucleic acid detection [2019-08]
C12Q 2561/00
Nucleic acid detection characterised by assay method [2019-08]
C12Q 2561/101
.
Taqman [2019-08]
C12Q 2561/107
.
Enzyme complementation [2019-08]
C12Q 2561/108
.
Hybridisation protection assay [HPA] [2019-08]
C12Q 2561/109
.
Invader technology [2019-08]
C12Q 2561/113
.
Real time assay [2019-08]
C12Q 2561/119
.
Fluorescence polarisation [2019-08]
C12Q 2561/12
.
Fluorescence lifetime measurement [2019-08]
C12Q 2561/125
.
Ligase Detection Reaction [LDR] [2019-08]
C12Q 2561/127
.
Protein truncation assay [2019-08]
C12Q 2563/00
Nucleic acid detection characterized by the use of physical, structural and functional properties [2019-08]
C12Q 2563/101
.
radioactivity, e.g. radioactive labels [2013-01]
C12Q 2563/103
.
luminescence [2013-01]
C12Q 2563/107
.
fluorescence [2013-01]
C12Q 2563/113
.
the label being electroactive, e.g. redox labels [2013-01]
C12Q 2563/116
.
electrical properties of nucleic acids, e.g. impedance, conductivity or resistance [2019-08]
C12Q 2563/119
.
the label being proteinic [2019-08]
C12Q 2563/125
.
the label being enzymatic, i.e. proteins, and non proteins, such as nucleic acid with enzymatic activity [2019-08]
C12Q 2563/131
.
the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin [2013-01]
C12Q 2563/137
.
Metal/ion, e.g. metal label [2017-01]
C12Q 2563/143
.
Magnetism, e.g. magnetic label [2013-01]
C12Q 2563/149
.
Particles, e.g. beads [2013-01]
C12Q 2563/155
.
Particles of a defined size, e.g. nanoparticles [2013-01]
C12Q 2563/157
.
Nanotubes or nanorods [2013-01]
C12Q 2563/159
.
Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components [2013-01]
C12Q 2563/161
.
Vesicles, e.g. liposome [2013-01]
C12Q 2563/167
.
Mass label [2013-01]
C12Q 2563/173
.
staining/intercalating agent, e.g. ethidium bromide [2013-01]
C12Q 2563/179
.
the label being a nucleic acid [2013-01]
C12Q 2563/185
.
Nucleic acid dedicated to use as a hidden marker/bar code, e.g. inclusion of nucleic acids to mark art objects or animals [2013-01]
C12Q 2565/00
Nucleic acid analysis characterised by mode or means of detection [2013-01]
C12Q 2565/10
.
Detection mode being characterised by the assay principle [2019-08]
C12Q 2565/101
. .
Interaction between at least two labels [2013-01]
C12Q 2565/1015
. . .
labels being on the same oligonucleotide [2013-01]
C12Q 2565/102
. .
Multiple non-interacting labels [2013-01]
C12Q 2565/1025
. . .
labels being on the same oligonucleotide [2013-01]
C12Q 2565/107
. .
Alteration in the property of hybridised versus free label oligonucleotides [2013-01]
C12Q 2565/113
. .
based on agglutination/precipitation [2013-01]
C12Q 2565/119
. .
based on extraction of label to an organic phase, i.e. partitioning of label between different organic phases [2013-01]
C12Q 2565/125
. .
Electrophoretic separation [2013-01]
C12Q 2565/131
. .
Single/double strand conformational analysis, i.e. SSCP/DSCP [2013-01]
C12Q 2565/133
. .
conformational analysis [2013-01]
C12Q 2565/137
. .
Chromatographic separation [2013-01]
C12Q 2565/20
.
Detection means characterised by being a gene reporter based analysis [2019-08]
C12Q 2565/201
. .
Two hybrid system [2013-01]
C12Q 2565/207
. .
Three hybrid system [2013-01]
C12Q 2565/30
.
Detection characterised by liberation or release of label [2019-08]
C12Q 2565/301
. .
Pyrophosphate (PPi) [2013-01]
C12Q 2565/40
.
Detection characterised by signal amplification of label [2019-08]
C12Q 2565/401
. .
Signal amplification by chemical polymerisation [2013-01]
C12Q 2565/50
.
Detection characterised by immobilisation to a surface [2013-01]
C12Q 2565/501
. .
being an array of oligonucleotides [2019-08]
C12Q 2565/507
. .
characterised by the density of the capture oligonucleotide [2013-01]
C12Q 2565/513
. .
characterised by the pattern of the arrayed oligonucleotides [2013-01]
C12Q 2565/514
. .
characterised by the use of the arrayed oligonucleotides as identifier tags, e.g. universal addressable array, anti-tag or tag complement array [2013-01]
C12Q 2565/515
. .
characterised by the interaction between or sequential use of two or more arrays [2013-01]
C12Q 2565/518
. .
characterised by the immobilisation of the nucleic acid sample or target [2013-01]
C12Q 2565/519
. .
characterised by the capture moiety being a single stranded oligonucleotide [2017-02]
C12Q 2565/525
. .
characterised by the capture oligonucleotide being double stranded [2013-01]
C12Q 2565/531
. .
characterised by the capture moiety being a protein for target oligonucleotides [2013-01]
C12Q 2565/537
. .
characterised by the capture oligonucleotide acting as a primer [2013-01]
C12Q 2565/543
. .
characterised by the use of two or more capture oligonucleotide primers in concert, e.g. bridge amplification [2019-08]
C12Q 2565/549
. .
characterised by the capture oligonucleotide being a reporter labelled capture oligonucleotide [2013-01]
C12Q 2565/60
.
Detection means characterised by use of a special device [2019-08]
C12Q 2565/601
. .
being a microscope, e.g. atomic force microscopy [AFM] [2013-01]
C12Q 2565/607
. .
being a sensor, e.g. electrode [2013-01]
C12Q 2565/619
. .
being a video camera [2013-01]
C12Q 2565/625
. .
being a nucleic acid test strip device, e.g. dipsticks, strips, tapes, CD plates [2016-08]
C12Q 2565/626
. .
being a flow cytometer [2013-01]
C12Q 2565/627
. .
being a mass spectrometer [2019-08]
C12Q 2565/628
. .
being a surface plasmon resonance spectrometer [2013-01]
C12Q 2565/629
. .
being a microfluidic device [2013-01]
C12Q 2565/631
. .
being a biochannel or pore [2013-01]
C12Q 2565/632
. .
being a surface enhanced, e.g. resonance, Raman spectrometer [2013-01]
C12Q 2565/633
. .
NMR [2013-01]
C12Q 2565/634
. .
being an acoustic wave sensor [2013-01]
C12Q 2600/00
Oligonucleotides characterized by their use [2019-08]
C12Q 2600/106
.
Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism [2013-01]
C12Q 2600/112
.
Disease subtyping, staging or classification [2013-01]
C12Q 2600/118
.
Prognosis of disease development [2013-01]
C12Q 2600/124
.
Animal traits, i.e. production traits, including athletic performance or the like [2013-01]
C12Q 2600/13
.
Plant traits [2013-01]
C12Q 2600/136
.
Screening for pharmacological compounds [2013-01]
C12Q 2600/142
.
Toxicological screening, e.g. expression profiles which identify toxicity [2013-01]
C12Q 2600/148
.
Screening for cosmetic compounds [2013-01]
C12Q 2600/154
.
Methylation markers [2013-01]
C12Q 2600/156
.
Polymorphic or mutational markers [2013-01]
C12Q 2600/158
.
Expression markers [2013-01]
C12Q 2600/16
.
Primer sets for multiplex assays [2013-01]
C12Q 2600/166
.
Oligonucleotides used as internal standards, controls or normalisation probes [2013-01]
C12Q 2600/172
.
Haplotypes [2013-01]
C12Q 2600/178
.
miRNA, siRNA or ncRNA [2013-01]