Journal articles and conference proceedings

The Office of the Chief Economist (OCE) publishes research findings from its team of economists and their collaborators in peer-reviewed economic journals and in law journals.

Patent eligibility after Alice: Evidence from USPTO patent examination

Jesse Frumkin, Nicholas A. Pairolero, Asrat Tesfayesus, and Andrew A. Toole
Journal of Economics & Management Strategy, 122.
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In a series of decisions over the last decade, the Supreme Court of the United States altered the classes of inventions that are eligible for patent protection—a body of law called subject matter eligibility. One of the more contentious of these decisions, Alice Corp. versus CLS Bank International (Alice), questioned the patentability of a broad class of inventions involving abstract ideas, particularly in digital technologies. Exploiting a quasinatural experiment, we find that the Alice decision reduced favorable patent eligibility decisions by 31% and significantly and persistently increased legal uncertainty in patent examination by 26% for a broad set of technologies. Our analysis quantifies how legal decisions can limit patent protection and highlights the need for further research on how greater legal uncertainty affects upstream investments supporting invention and downstream innovations fueling growth.

Discovering value: women’s participation in university and commercial AI invention

Alexander V. Giczy, Nicholas A. Pairolero, and Andrew A. Toole
Nature Biotechnology, Volume 42, January 2024, pg. 26-29
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Listen to AUTM on the Air podcast ("Behind the Numbers: Insights from U.S. Patenting on Diagnosing COVID-19")

More can be done to diversify the AI innovation ecosystem, especially in the emerging field of biotechnology AI, where women’s participation is associated with substantial value. 


How does digital piracy affect innovation? Evidence from software firms

Wendy A. Bradley and Julian Kolev
Research Policy, Volume 52, Issue 3, April 2023
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Closing the Gender Gap in Patenting: Evidence from a Randomized Control Trial at the USPTO

Nicholas A. Pairolero, Andrew A. Toole, Peter-Anthony Pappas, Charles A.W. deGrazia, Mike H.M. Teodorescu
Academy of Management Proceedings , vol 2022, no 1, July 2022
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Challenges facing independent inventors: Do patents help?

Charles A.W. deGrazia, Nicholas A. Pairolero, Peter-Anthony Pappas, Andrew A. Toole, Mike H.M. Teodorescu
Academy of Management Proceedings, vol 2022, no 1, July 2022
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Identifying artificial intelligence (AI) invention: A novel AI patent dataset

Alexander V. Giczy, Nicholas A. Pairolero, and Andrew Toole
The Journal of Technology Transfer, 2021
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Examination incentives, learning, and patent office outcomes: The use of examiner’s amendments at the USPTO

Charles A.W. deGrazia, Nicholas A. Pairolero, and Mike H.M. Teodorescu
Research Policy, vol 50, issue 10, December 2021
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The Promise of Machine Learning for Patent Landscaping

Andrew A. Toole, Nicholas A. Pairolero, James Q. Forman, and Alexander V. Giczy
Santa Clara High Technology Law Journal, vol 36, no 4, May 2020
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Innovation activities and business cycles: are trademarks a leading indicator?

Charles A. W. deGrazia, Amanda Myers, and Andrew A. Toole
Industry and Innovation, vol 27, issue 1-2, 2020
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