Class   435	CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
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1.1

DIFFERENTIATED TISSUE OR ORGAN OTHER THAN BLOOD, PER SE, OR DIFFERENTIATED TISSUE OR ORGAN MAINTAINING; COMPOSITION THEREFOR

1.2

. (1 indent ) Including perfusion; composition therefor

1.3

. (1 indent ) Including freezing; composition therefor

2

MAINTAINING BLOOD OR SPERM IN A PHYSIOLOGICALLY ACTIVE STATE OR COMPOSITIONS THEREOF OR THEREFOR OR METHODS OF IN VITRO BLOOD CELL SEPARATION OR TREATMENT

3

CONDITION RESPONSIVE CONTROL PROCESS

4

MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP

5

. (1 indent ) Involving virus or bacteriophage

6

. (1 indent ) Involving nucleic acid

7.1

. (1 indent ) Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay

7.2

.. (2 indent ) Involving a micro-organism or cell membrane bound antigen or cell membrane bound receptor or cell membrane bound antibody or microbial lysate

7.21

... (3 indent ) Animal cell

7.22

.... (4 indent ) Parasite or protozoa

7.23

.... (4 indent ) Tumor cell or cancer cell

7.24

.... (4 indent ) Leukocyte (e.g., lymphocyte, granulocyte, monocyte, etc.)

7.25

.... (4 indent ) Erythrocyte

7.3

... (3 indent ) Flagellar-antigen or pili-antigen

7.31

... (3 indent ) Fungi (e.g., yeast, mold, etc.)

7.32

... (3 indent ) Bacteria or actinomycetales

7.33

.... (4 indent ) Staphylococcus

7.34

.... (4 indent ) Streptococcus

7.35

.... (4 indent ) Salmonella

7.36

.... (4 indent ) Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.)

7.37

.... (4 indent ) Escherichia coli

7.4

.. (2 indent ) To identify an enzyme or isoenzyme

7.5

.. (2 indent ) Involving avidin-biotin binding

7.6

.. (2 indent ) Involving a modified enzyme (e.g., abzyme, recombinant, chemically altered, etc.)

7.7

.. (2 indent ) Assay in which a label present is an apoenzyme, prosthetic group, or enzyme cofactor

7.71

.. (2 indent ) Assay in which a label present is an enzyme inhibitor or functions to alter enzyme activity

7.72

.. (2 indent ) Assay in which a label present is an enzyme substrate or substrate analogue

7.8

.. (2 indent ) Involving nonmembrane bound receptor binding or protein binding other than antigen-antibody binding

7.9

.. (2 indent ) Assay in which an enzyme present is a label

7.91

... (3 indent ) Enzyme produces product which is part of another reaction system (e.g., cyclic reaction, cascade reaction, etc.)

7.92

... (3 indent ) Heterogeneous or solid phase assay system (e.g., ELISA, etc.)

7.93

.... (4 indent ) Competitive assay

7.94

.... (4 indent ) Sandwich assay

7.95

.... (4 indent ) Indirect assay

8

. (1 indent ) Involving luciferase

9

. (1 indent ) Geomicrobiological testing (e.g., for petroleum, etc.)

10

. (1 indent ) Involving uric acid

11

. (1 indent ) Involving cholesterol

12

. (1 indent ) Involving urea or urease

13

. (1 indent ) Involving blood clotting factor (e.g., involving thrombin, thromboplastin, fibrinogen, etc.)

14

. (1 indent ) Involving glucose or galactose

15

. (1 indent ) Involving transferase

16

.. (2 indent ) Involving transaminase

17

.. (2 indent ) Involving creatine phosphokinase

18

. (1 indent ) Involving hydrolase

19

.. (2 indent ) Involving esterase

20

... (3 indent ) Involving cholinesterase

21

... (3 indent ) Involving phosphatase

22

.. (2 indent ) Involving amylase

23

.. (2 indent ) Involving proteinase

24

.. (2 indent ) Involving peptidase

25

. (1 indent ) Involving oxidoreductase

26

.. (2 indent ) Involving dehydrogenase

27

.. (2 indent ) Involving catalase

28

.. (2 indent ) Involving peroxidase

29

. (1 indent ) Involving viable micro-organism

30

.. (2 indent ) Methods of sampling or inoculating or spreading a sample; methods of physically isolating an intact micro-organism

31

.. (2 indent ) Testing for sterility condition

32

.. (2 indent ) Testing for antimicrobial activity of a material

33

... (3 indent ) Using multifield media

34

.. (2 indent ) Determining presence or kind of micro-organism; use of selective media

35

... (3 indent ) Using radioactive material

36

... (3 indent ) Streptococcus; staphylococcus

37

... (3 indent ) Nitrate to nitrite reducing bacteria

38

... (3 indent ) Enterobacteria

39

... (3 indent ) Quantitative determination

40

.... (4 indent ) Using multifield media

40.5

. (1 indent ) Involving fixed or stabilized, nonliving microorganism, cell, or tissue (e.g., processes of staining, stabilizing, dehydrating, etc.; compositions used therefore, etc.)

40.51

.. (2 indent ) Involving a monolayer, smear or suspension of microorganisms or cells

40.52

.. (2 indent ) Involving tissue sections

41

MICRO-ORGANISM, TISSUE CELL CULTURE OR ENZYME USING PROCESS TO SYNTHESIZE A DESIRED CHEMICAL COMPOUND OR COMPOSITION

42

. (1 indent ) Process involving micro-organisms of different genera in the same process, simultaneously

43

. (1 indent ) Preparing compound having a 1-thia-4-aza-bicyclo (3.2.0) heptane ring system (e.g., penicillin, etc.)

44

.. (2 indent ) By desacylation of the substituent in 6-position

45

.. (2 indent ) By acylation of the substituent in 6-position

46

.. (2 indent ) In presence of phenyl acetic acid or phenyl acetamide or their derivatives

47

. (1 indent ) Preparing compound having a 1-thia-5-aza-bicyclo (4.2.0) octane ring system (e.g., cephalosporin, etc.)

48

.. (2 indent ) Di-substituted in 7-position

49

.. (2 indent ) Cephalosporin C

50

.. (2 indent ) By acylation of the substituent in the 7-position

51

.. (2 indent ) By desacylation of the substituent in the 7-position

52

. (1 indent ) Preparing compound containing a cyclopentanohydrophenanthrene nucleus; nor-, homo-, or D-ring lactone derivatives thereof

53

.. (2 indent ) Containing heterocyclic ring

54

.. (2 indent ) Acting on D-ring

55

... (3 indent ) Acting at 17-position

56

.... (4 indent ) Hydroxylating at 17-position

57

... (3 indent ) Hydroxylating at 16-position

58

.. (2 indent ) Hydroxylating

59

... (3 indent ) At 11-position

60

.... (4 indent ) At 11 alpha position

61

.. (2 indent ) Dehydrogenating; dehydroxylating

62

... (3 indent ) Forming an aryl ring from "A" ring

63

. (1 indent ) Preparing compound containing a prostaglandin nucleus

64

. (1 indent ) Preparing compound other than saccharide containing a tetracycline nucleus (e.g., naphacene, etc.)

65

. (1 indent ) Preparing compound other than saccharide containing a gibberellin nucleus (i.e., gibbane)

66

. (1 indent ) Preparing compound other than saccharide containing alloxazine or isoalloxazine nucleus

67

. (1 indent ) Preparing compound containing a carotene nucleus (i.e., carotene)

68.1

. (1 indent ) Enzymatic production of a protein or polypeptide (e.g., enzymatic hydrolysis, etc.)

69.1

. (1 indent ) Recombinant DNA technique included in method of making a protein or polypeptide

69.2

.. (2 indent ) Enzyme inhibitors or activators

69.3

.. (2 indent ) Antigens

69.4

.. (2 indent ) Hormones and fragments thereof

69.5

.. (2 indent ) Lymphokines or monokines

69.51

... (3 indent ) Interferons

69.52

... (3 indent ) Interleukins

69.6

.. (2 indent ) Blood proteins

69.7

.. (2 indent ) Fusion proteins or polypeptides

69.8

.. (2 indent ) Signal sequence (e.g., beta-galactosidase, etc.)

69.9

... (3 indent ) Yeast derived

70.1

. (1 indent ) Using tissue cell culture to make a protein or polypeptide

70.2

.. (2 indent ) Fused or hybrid cells

70.21

... (3 indent ) Producing monoclonal antibody

70.3

.. (2 indent ) Animal tissue cell culture

70.4

... (3 indent ) Blood (lymphoid) cell culture

70.5

.... (4 indent ) Producing interferons

71.1

. (1 indent ) Using a micro-organism to make a protein or polypeptide

71.2

.. (2 indent ) Procaryotic micro-organism

71.3

... (3 indent ) Antibiotic or toxin

72

. (1 indent ) Preparing compound containing saccharide radical

73

.. (2 indent ) Preparing S-glycoside (e.g., lincomycin, etc.)

74

.. (2 indent ) Preparing O-glycoside (e.g., glucosides, etc.)

75

... (3 indent ) Oxygen of the saccharide radical is directly bonded to a nonsaccharide heterocyclic ring or a fused- or bridged-ring system which contains a nonsaccharide heterocyclic ring (e.g., coumermycin, novobiocin, etc.)

76

.... (4 indent ) The hetero ring has eight or more ring members and only oxygen as ring hetero atoms (e.g., erythromycin, spiramycin, nystatin, etc.)

77

... (3 indent ) Oxygen atom of the saccharide radical is directly linked through only acyclic carbon atoms to a nonsaccharide heterocyclic ring (e.g., bleomycin, phleomycin, etc.)

78

... (3 indent ) Oxygen atom of the saccharide radical is directly bonded to a condensed ring system having three or more carboxyclic rings (e.g., dauomycin, adriamycin, etc.)

79

... (3 indent ) Oxygen atom of the saccharide radical is bonded to a cyclohexyl radical (e.g., kasugamycin, etc.)

80

.... (4 indent ) Cyclohexyl radical is substituted by two or more nitrogen atoms (e.g., destomycin, neamin, etc.)

81

....• (5 indent ) Cyclohexyl radical is attached directly to a nitrogen atom of two or more N-C(=N)-N radicals (e.g., streptomycin, etc.)

82

....• (5 indent ) Having two saccharide radicals bonded through only oxygen to adjacent ring carbons of the cyclohexyl radical (e.g., ambutyrosin, ribostamycin, etc.)

83

....•. (6 indent ) Containing three or more saccharide radicals (e.g., liquidomycin, neomycin, lividomycin, etc.)

84

.. (2 indent ) Preparing nitrogen-containing saccharide

85

... (3 indent ) N-glycoside

86

.... (4 indent ) Cobalamin (i.e., vitamin B12, LLD factor)

87

.... (4 indent ) Nucleoside

88

....• (5 indent ) Having a fused ring containing a six-membered ring having two N-atoms in the same ring (e.g., purine nucleosides, etc.)

89

.... (4 indent ) Nucleotide

90

....• (5 indent ) Dinucleotide (e.g., NAD, etc.)

91.1

....• (5 indent ) Polynucleotide (e.g., nucleic acid, oligonucleotide, etc.)

91.2

....•. (6 indent ) Acellular exponential or geometric amplification (e.g., PCR, etc.)

91.21

....•.. (7 indent ) Involving the making of multiple RNA copies

91.3

....•. (6 indent ) Polynucleotide contains only ribonucleotide monomers

91.31

....•.. (7 indent ) Involving catalytic ribonucleic acid

91.32

....•.. (7 indent ) Prepared from virus, prokaryotic acid

91.33

....•... (8 indent ) Involving virus

91.4

....•. (6 indent ) Modification or preparation of a recombinant DNA vector

91.41

....•.. (7 indent ) By insertion or addition of one or more nucleotides

91.42

....•.. (7 indent ) Involving deletion of a nucleotide or nucleotides from a vector

91.5

....•. (6 indent ) Acellular preparation of polynucleotide

91.51

....•.. (7 indent ) Involving RNA as a starting material or intermediate

91.52

....•.. (7 indent ) Involving a ligase (6.)

91.53

....•.. (7 indent ) Involving a hydrolase (3.)

92

....• (5 indent ) Having a fused ring containing a six-membered ring having two N-atoms in the same ring (e.g., purine based mononucleotides, etc.)

93

.. (2 indent ) Mashing or wort making

94

.. (2 indent ) Produced by the action of an isomerase (e.g., fructose by the action of xylose isomerase on glucose, etc.)

95

.. (2 indent ) Produced by the action of a beta-amylase (e.g., maltose by the action of beta-amylase on amylose, etc.)

96

.. (2 indent ) Produced by the action of an exo-1.4 alpha glucosidase (e.g., dextrose by the action of glucoamylase on starch, etc.)

97

.. (2 indent ) Produced by the action of a glycosyl transferase (e.g., alpha, beta, gamma-cyclodextrins by the action of glycosyl transferase on starch, etc.)

98

.. (2 indent ) Produced by the action of an alpha-1, 6-glucosidase (e.g., amylose debranched amylopectin by the action of pullulanase, etc.)

99

.. (2 indent ) Produced by the action of a carbohydrase (e.g., maltose by the action of alpha amylase on starch, etc.)

100

.. (2 indent ) Disaccharide

101

.. (2 indent ) Polysaccharide of more than five saccharide radicals attached to each other by glycosidic bonds

102

... (3 indent ) Pullulan

103

... (3 indent ) Dextran

104

... (3 indent ) Xanthan; i.e., xanthomonas-type heteropolysaccharides

105

.. (2 indent ) Monosaccharide

106

. (1 indent ) Preparing alpha or beta amino acid or substituted amino acid or salts thereof

107

.. (2 indent ) Proline; hydroxyproline; histidine

108

.. (2 indent ) Tryptophan; tyrosine; phenylalanine; 3,4 dihydroxyphenylalanine

109

.. (2 indent ) Aspartic acid (asparaginic acid); asparagine

110

.. (2 indent ) Glutamic acid; glutamine

111

... (3 indent ) Utilizing biotin or its derivatives

112

... (3 indent ) Utilizing surfactant fatty acids or fatty acid esters (i.e., having seven or more atoms)

113

.. (2 indent ) Methionine; cysteine; cystine

114

.. (2 indent ) Citrulline; arginine; ornithine

115

.. (2 indent ) Lysine; diaminopimelic acid; threonine; valine

116

.. (2 indent ) Alanine; leucine; isoleucine; serine; homoserine

117

. (1 indent ) Preparing heterocyclic carbon compound having only O, N, S, Se, or Te as ring hetero atoms

118

.. (2 indent ) Containing two or more hetero rings

119

... (3 indent ) Containing at least two hetero rings bridged or fused among themselves or bridged or fused with a common carbocyclic ring system, (e.g., rifamycin, etc.)

120

.. (2 indent ) Nitrogen or oxygen hetero atom and at least one other diverse hetero ring atom in the same ring

121

.. (2 indent ) Nitrogen as only ring hetero atom

122

... (3 indent ) Containing six-membered hetero ring

123

.. (2 indent ) Oxygen as only ring hetero atom

124

... (3 indent ) Containing a hetero ring of at least seven ring members (e.g., zearalenone, macrocyclic lactones, etc.)

125

... (3 indent ) Containing six-membered hetero ring (e.g., fluorescein, etc.)

126

... (3 indent ) Containing five-membered hetero ring (e.g., griseofulvin, etc.)

127

. (1 indent ) Preparing compound containing at least three carbocyclic rings

128

. (1 indent ) Preparing nitrogen-containing organic compound

129

.. (2 indent ) Amide (e.g., chloramphenicol, etc.)

130

. (1 indent ) Preparing sulfur-containing organic compound

131

. (1 indent ) Preparing organic compound containing a metal or atom other than H, N, C, O, or halogen

132

. (1 indent ) Preparing oxygen-containing organic compound

133

.. (2 indent ) Containing quinone nucleus (i.e., quinoid structure)

134

.. (2 indent ) Fat; fatty oil; ester-type wax; higher fatty acid (i.e., having at least seven carbon atoms in an unbroken chain bound to a carboxyl group); oxidized oil or fat

135

.. (2 indent ) Carboxylic acid ester

136

.. (2 indent ) Containing a carboxyl group

137

... (3 indent ) Sugar acid having five or more carbon atoms (i.e., aldonic, keto-aldonic, or saccharic acid)

138

.... (4 indent ) Alpha-ketogulonic acid (i.e., 2-ketogulonic acid)

139

... (3 indent ) Lactic acid

140

... (3 indent ) Acetic acid

141

... (3 indent ) Propionic or butyric acid

142

... (3 indent ) Polycarboxylic acid

143

.... (4 indent ) Having keto group (e.g., alpha-ketoglutaric acid, etc.)

144

.... (4 indent ) Tricarboxylic acid (e.g., citric acid, etc.)

145

.... (4 indent ) Dicarboxylic acid having four or less carbon atoms (e.g., fumaric, maleic, etc.)

146

... (3 indent ) Hydroxy carboxylic acid

147

.. (2 indent ) Containing carbonyl group

148

... (3 indent ) Ketone

149

.... (4 indent ) Cyclopentanone or cyclopentadione containing compound

150

.... (4 indent ) Acetone containing product

151

....• (5 indent ) Substrate contains grain or cereal material

152

....• (5 indent ) Substrate contains protein as nitrogen source

153

....• (5 indent ) Substrate contains inorganic nitrogen source

154

....• (5 indent ) Substrate contains inorganic compound, other than water

155

.. (2 indent ) Containing hydroxy group

156

... (3 indent ) Aromatic

157

... (3 indent ) Acyclic

158

.... (4 indent ) Polyhydric

159

....• (5 indent ) Glycerol

160

.... (4 indent ) Butanol

161

.... (4 indent ) Ethanol

162

....• (5 indent ) Multiple stages of fermentation; multiple types of micro-organisms or reuse of micro-organisms

163

....• (5 indent ) Produced as by-product, or from waste, or from cellulosic material substrate

164

....•. (6 indent ) Substrate contains sulphite waste liquor or citrus waste

165

....•. (6 indent ) Substrate contains cellulosic material

166

. (1 indent ) Preparing hydrocarbon

167

.. (2 indent ) Only acyclic

168

. (1 indent ) Preparing element or inorganic compound except carbon dioxide

169

. (1 indent ) Using actinomycetales

170

. (1 indent ) Using bacteria

171

. (1 indent ) Using fungi

440

PROCESS OF MUTATION, CELL FUSION, OR GENETIC MODIFICATION

441

. (1 indent ) Mutation employing a chemical mutagenic agent

442

.. (2 indent ) By replacement of standard nucleic acid base with base analog (e.g., 5-bromouracil, etc.)

443

.. (2 indent ) By use of intercalating agent (e.g., acridine orange, etc.)

444

.. (2 indent ) By use of alkylating agent (e.g., nitrosoguanidine, etc.)

445

.. (2 indent ) By use of oxidative deamination agent (e.g., nitrous acid, etc.)

446

. (1 indent ) Mutation employing radiation or electricity

447

.. (2 indent ) X-ray irradiation

448

.. (2 indent ) Ultraviolet irradiation

449

. (1 indent ) Fusion of cells

450

.. (2 indent ) Employing electric current

451

.. (2 indent ) One of the fusing cells is a human antibody-producing cell

452

.. (2 indent ) One of the fusing cells is a mouse antibody-producing cell

453

.. (2 indent ) One of the fusing cells is a plant cell

454

.. (2 indent ) One of the fusing cells is a microorganism (e.g., prokaryote, fungus, etc.)

455

. (1 indent ) Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell

456

.. (2 indent ) The polynucleotide is encapsidated within a virus or viral coat

457

... (3 indent ) Helper virus is present

458

.. (2 indent ) The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.)

459

.. (2 indent ) Involving particle-mediated transfection (i.e., biolistic transfection)

460

.. (2 indent ) Involving laser treatment of the cell before or during transfection

461

.. (2 indent ) Involving electroporation

462

.. (2 indent ) Involving site-specific recombination (e.g., Cre-lox, etc.)

463

.. (2 indent ) Involving general or homologous recombination (e.g., gene targeting, etc.)

464

.. (2 indent ) Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.)

465

.. (2 indent ) Involving co-transfection

466

.. (2 indent ) The polynucleotide is a shuttle vector or a transiently replicating hybrid vector

467

.. (2 indent ) Introducing an oncogene to establish a cell line

468

. (1 indent ) Introduction of a polynucleotide molecule into or rearrangement of a nucleic acid within a plant cell

469

.. (2 indent ) Introduction via Agrobacterium

470

.. (2 indent ) Introduction via electroporation, particle, fiber or microprojectile mediated insertion, or injection

471

. (1 indent ) Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within a microorganism (e.g., bacteria, protozoa, bacteriophage, etc.)

472

.. (2 indent ) The polynucleotide is encapsidated within a bacteriophage, bacteriophage coat, or transducing particle

473

.. (2 indent ) The polynucleotide contains a transposon

474

.. (2 indent ) The polynucleotide is a cosmid

475

.. (2 indent ) The polynucleotide is unencapsidated bacteriophage or viral nucleic acid

476

.. (2 indent ) The polynucleotide is a plasmid or episome

477

... (3 indent ) Plasmid or episome contains DNA targeting homologous recombination to bacteriophage, viral, or chromosomal DNA within a microorganism

478

... (3 indent ) Plasmid or episome contains at least part of a gene encoding a restriction endonuclease or modification enzyme

479

... (3 indent ) Plasmid or episome confers the ability to utilize directly a compound which a wild type microorganism is unable to utilize

480

... (3 indent ) Plasmid or episome contains at least part of a gene encoding a toxin or encoding for virulence or pathogenicity

481

... (3 indent ) Plasmid or episome contains a gene which complements a nutritional deficiency mutation

482

... (3 indent ) Plasmid or episome contains a gene which confers resistance to metal, silicon, selenium, or tellurium toxicity

483

... (3 indent ) Yeast is a host for the plasmid or episome

484

... (3 indent ) Mycelial fungus is a host for the plasmid or episome

485

... (3 indent ) Microorganism of the genus Bacillus is a host for the plasmid or episome

486

... (3 indent ) Microorganism of the genus Streptomyces is a host for the plasmid or episome

487

... (3 indent ) Microorganism of the genus Brevibacterium or the genus Corynebacterium is a host for the plasmid or episome

488

... (3 indent ) Microorganism of the genus Escherichia is a host for the plasmid or episome

489

... (3 indent ) Plural nonidentical plasmids are introduced into a host microorganism or culture thereof (e.g., plasmid is part of a library, etc.)

490

.. (2 indent ) The polynucleotide is an unbranched linear fragment

173.1

TREATMENT OF MICRO-ORGANISMS OR ENZYMES WITH ELECTRICAL OR WAVE ENERGY (E.G., MAGNETISM, SONIC WAVES, ETC.)

173.2

. (1 indent ) Enzyme treated

173.3

. (1 indent ) Modification of viruses (e.g., attenuation, etc.)

173.4

. (1 indent ) Cell membrane or cell surface is target

173.5

.. (2 indent ) Membrane permeability increased

173.6

... (3 indent ) Electroporation

173.7

.. (2 indent ) Lytic effect produced (e.g., disruption of cell membrane for release of subcellular parts; e.g., nucleic acids, etc.)

173.8

. (1 indent ) Metabolism of micro-organism enhanced (e.g., growth enhancement or increased production of microbial product)

173.9

. (1 indent ) Concentration, separation, or purification of micro-organisms

174

CARRIER-BOUND OR IMMOBILIZED ENZYME OR MICROBIAL CELL; CARRIER-BOUND OR IMMOBILIZED CELL; PREPARATION THEREOF

175

. (1 indent ) Multi-enzyme system

176

. (1 indent ) Enzyme or microbial cell is immobilized on or in an inorganic carrier

177

. (1 indent ) Enzyme or microbial cell is immobilized on or in an organic carrier

178

.. (2 indent ) Carrier is carbohydrate

179

... (3 indent ) Carbohydrate is cellulose or derivative thereof

180

.. (2 indent ) Carrier is synthetic polymer

181

... (3 indent ) Attached to the carrier via a bridging agent

182

... (3 indent ) Enzyme or microbial cell is entrapped within the carrier (e.g., gel, hollow fibre)

183

ENZYME (E.G., LIGASES (6. ), ETC.), PROENZYME; COMPOSITIONS THEREOF; PROCESS FOR PREPARING, ACTIVATING, INHIBITING, SEPARATING, OR PURIFYING ENZYMES

184

. (1 indent ) Enzyme inactivation by chemical treatment

185

. (1 indent ) Malt

186

. (1 indent ) Pancreatin

187

. (1 indent ) Preparing granular- or free-flowing enzyme composition

188

. (1 indent ) Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate

188.5

. (1 indent ) Catalytic antibody

189

. (1 indent ) Oxidoreductase (1. ) (e.g., luciferase)

190

.. (2 indent ) Acting on CHOH group as donor (e.g., glucose oxidase, lactate dehydrogenase (1.1))

191

.. (2 indent ) Acting on nitrogen-containing compound as donor (1.2, 1.5, 1.7)

192

.. (2 indent ) Acting on hydrogen peroxide as acceptor (1.11)

193

. (1 indent ) Transferase other than ribonuclease (2.)

194

.. (2 indent ) Transferring phosphorus containing group (e.g., kineases, etc.(2.7))

195

. (1 indent ) Hydrolase (3. )

196

.. (2 indent ) Acting on ester bond (3.1)

197

... (3 indent ) Carboxylic ester hydrolase (3.1.1)

198

.... (4 indent ) Triglyceride splitting (e.g., lipase, etc. (3.1.1.3))

199

... (3 indent ) Ribonuclease (3.1.4)

200

.. (2 indent ) Acting on glycosyl compound (3.2)

201

... (3 indent ) Acting on alpha-1, 4-glucosidic bond, (e.g., hyaluronidase, invertase, amylase, etc. (some 3.2.1))

202

.... (4 indent ) Alpha-amylase, microbial source

203

....• (5 indent ) Fungal source

204

.... (4 indent ) Alpha-amylase, plant source (3.2.1.1)

205

.... (4 indent ) Glucoamylase (3.2.1.3)

206

... (3 indent ) Acting on beta-1, 4 link between N-acetylmuramic acid and 2-acetylamino 2 deoxy-D-glucose (e.g., lysozyme, etc.)

207

... (3 indent ) Acting on beta-galatose-glycoside bond (e.g., beta-galactosidase, etc.)

208

... (3 indent ) Acting on alpha-galatose-glycoside bond (e.g., alpha-galactosidase, etc.)

209

... (3 indent ) Acting on beta-1, 4-glucosidic bond (e.g., cellulase, etc. (3.2.1.4))

210

... (3 indent ) Acting on alpha-1, 6-glucosidic bond (e.g., isoamylase, pullulanase, etc.)

211

.... (4 indent ) Dextranase (3.2.1.11)

212

.. (2 indent ) Acting on peptide bond (e.g., thromboplastin, leucine amino-peptidase, etc., (3.4))

213

... (3 indent ) Trypsin; chymotrypsin

214

... (3 indent ) Thrombin

215

... (3 indent ) Urokinase

216

... (3 indent ) Streptokinase

217

... (3 indent ) Plasmin (i.e., fibrinolysin)

218

... (3 indent ) Elastase

219

... (3 indent ) Proteinase

220

.... (4 indent ) Derived from bacteria

221

....• (5 indent ) Bacteria is bacillus

222

....•. (6 indent ) Bacillus subtilus or bacillus lichenoformis

223

.... (4 indent ) Derived from fungi

224

....• (5 indent ) From yeast

225

....• (5 indent ) From aspergillus

226

.... (4 indent ) Derived from animal tissue (e.g., rennin, etc.)

227

.. (2 indent ) Acting on carbon to nitrogen bond other than peptide bond (3.5)

228

... (3 indent ) Acting on a linear amide linkage in linear amide

229

.... (4 indent ) Asparaginase

230

.... (4 indent ) Penicillin amidase

231

... (3 indent ) Acting on amide linkage in cyclic amides (e.g., penicillinase, etc.) (3.5.2)

232

. (1 indent ) Lyase (4. )

233

. (1 indent ) Isomerase (5. )

234

.. (2 indent ) Glucose isomerase

235.1

VIRUS OR BACTERIOPHAGE, EXCEPT FOR VIRAL VECTOR OR BACTERIOPHAGE VECTOR; COMPOSITION THEREOF; PREPARATION OR PURIFICATION THEREOF; PRODUCTION OF VIRAL SUBUNITS; MEDIA FOR PROPAGATING

236

. (1 indent ) Inactivation or attenuation; producing viral subunits

237

.. (2 indent ) By serial passage of virus

238

.. (2 indent ) By chemical treatment

239

. (1 indent ) Recovery or purification

325

ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE

326

. (1 indent ) Animal cell, per se, expressing immunoglobulin, antibody, or fragment thereof

327

.. (2 indent ) Immunoglobulin or antibody is anti-idiotypic

328

.. (2 indent ) Immunoglobulin or antibody is chimeric, mutated, or a recombined hybrid (e.g., bifunctional, bispecific, rodent-human chimeric, single chain, rFv, immunoglobuin fusion protein, etc.)

329

.. (2 indent ) Immunoglobulin or antibody binds an oligosaccharide structure other than nucleic acid

330

.. (2 indent ) Immunoglobulin or antibody binds an expression product of a cancer related gene or fragment thereof (e.g., oncogene, proto-oncogene, etc.)

331

.. (2 indent ) Immunoglobulin or antibody binds a specifically identified amino acid sequence

332

.. (2 indent ) Immunoglobulin or antibody binds a microorganism or normal or mutant component or product thereof (e.g., animal cell, cell surface antigen, secretory product, etc.)

333

... (3 indent ) Binds a nucleic acid or derivative or component thereof (e.g., DNA, RNA, DNA-RNA, hybrid, nucleotide, nucleoside, carcinogen-DNA adduct, etc.)

334

... (3 indent ) Binds a receptor (e.g., transferrin receptor, Fc receptor, dihydropyridine receptor, IL-2 receptor, etc.)

335

... (3 indent ) Binds a lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

336

... (3 indent ) Binds a hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)

337

... (3 indent ) Binds a plasma protein, serum protein, or fibrin (e.g., clotting factor fibrinolytic factor, complement factor, immunoglobulin, apolipoprotein, etc.)

338

... (3 indent ) Binds an enzyme

339

... (3 indent ) Binds a virus or component or product thereof (e.g., virus associated antigen, etc.)

339.1

.... (4 indent ) Binds a retrovirus or component or product thereof (e.g., HIV, LAV, HTLV, etc.)

340

... (3 indent ) Binds a bacterium or similar microorganism or component or product thereof (e.g., Streptococcus, Legionella, Mycoplasma, bacterium associated antigen, exotoxin, etc.)

341

... (3 indent ) Binds a fungus or plant cell or component or product thereof (e.g., fungus associated antigen, etc.)

342

... (3 indent ) Binds a parasitic protozoan or metazoan cell or component or product thereof; (e.g., Dirofilaria, Eimeria, Coccidia, Trichinella, parasite cell surface antigen, etc.)

343

... (3 indent ) Binds a hematopoietic cell or component or product thereof (e.g., erythrocyte, granulocyte, macrophage, monocyte, platelet, myelogenous leukemia cell, bone marrow stem cell, granulocytic cell surface antigen, hemoglobin, thrombospondin, glycophorin, etc.)

343.1

.... (4 indent ) Binds a lymphocytic or lymphocytic-like cell or component or product thereof (e.g., B cell, B-lineage bone marrow cell, null cell, natural killer cell, B-lymphoblastoid cell, B-lineage, acute lymphoblastic leukemia cell, B-lymphocytic cell surface antigen, etc.)

343.2

....• (5 indent ) Binds a T-lymphocytic cell or component or product thereof (e.g., T-cell, thymocyte, T-lineage bone marrow cell, T-lymphoblastoid cell, T-lineage acute lymphoblastic leukemia cell, T-lymphocytic cell surface antigen, etc.)

344

... (3 indent ) Binds a cancer cell or component or product thereof (e.g., cell surface antigen, etc.)

344.1

.... (4 indent ) Binds an antigen characterized by name or molecular weight (e.g., CEA, NCA, CC glycoprotein, melanoma gp 150 antigen, etc.)

345

.. (2 indent ) Immunoglobulin or antibody binds a drug, hapten, hapten-carrier complex, or specifically identified chemical structure (e.g., theophylline, digoxin, etc.)

346

. (1 indent ) Fused or hybrid cell, per se

347

. (1 indent ) Two or more cell types, per se, in co-culture

348

. (1 indent ) Insect cell, per se

349

. (1 indent ) Avian cell, per se

350

. (1 indent ) Canine cell, per se

351

. (1 indent ) Feline cell, per se

352

. (1 indent ) Rodent cell, per se

353

.. (2 indent ) Rat (i.e., Rattus)

354

.. (2 indent ) Mouse (i.e., Mus)

355

... (3 indent ) Blood or lymphatic origin or derivative

356

... (3 indent ) L cell or derivative (e.g., Ltk(-), etc.)

357

... (3 indent ) Fibroblast, fibroblast-like cell or derivative (e.g., NIH 3T3, etc.)

358

.. (2 indent ) Chinese hamster ovary (i.e., CHO)

359

... (3 indent ) Expressing recombinant tPA

360

... (3 indent ) Expressing recombinant hormone or growth factor

361

... (3 indent ) Expressing recombinant receptor

362

... (3 indent ) Expressing recombinant antigen

363

. (1 indent ) Primate cell, per se

364

.. (2 indent ) Monkey kidney

365

... (3 indent ) COS (e.g., COS-7, etc.)

365.1

.... (4 indent ) Expressing recombinant lymphokine, interferon, hormone, growth factor or morphogen

366

.. (2 indent ) Human

367

... (3 indent ) HeLa cell or derivative

368

... (3 indent ) Nervous system origin or derivative

369

... (3 indent ) Renal origin or derivative

370

... (3 indent ) Hepatic origin or derivative

371

... (3 indent ) Epithelial origin or derivative

372

... (3 indent ) Blood, lymphatic, or bone marrow origin or derivative

372.1

.... (4 indent ) Myeloma origin or derivative

372.2

.... (4 indent ) B-cell or derivative

372.3

.... (4 indent ) T-cell or derivative

373

. (1 indent ) Method of co-culturing cells

374

. (1 indent ) Method of storing cells in a viable state

375

. (1 indent ) Method of regulating cell metabolism or physiology

376

.. (2 indent ) Method of synchronizing cell division

377

.. (2 indent ) Method of altering the differentiation state of the cell

378

. (1 indent ) Method of detaching cells, digesting tissue or establishing a primary culture

379

.. (2 indent ) Using mechanical means (e.g., trituration, etc.)

380

.. (2 indent ) Releasing bound or adhered cell using protease

381

.. (2 indent ) Digesting tissue with protease

382

. (1 indent ) Method of culturing encapsulated cells

383

. (1 indent ) Method of culturing cells in suspension

384

.. (2 indent ) Culture medium contains a growth factor or growth regulator

385

... (3 indent ) Medium contains a colony stimulating factor

386

... (3 indent ) Medium contains an interleukin

387

... (3 indent ) Medium contains a polypeptide hormone

388

.. (2 indent ) Culture medium contains an albumin

389

.. (2 indent ) Culture medium contains a transferrin

390

.. (2 indent ) Culture medium contains an incompletely defined plant or microbial extract excluding animal extract

391

.. (2 indent ) Culture medium contains an animal extract

392

... (3 indent ) Serum

393

.. (2 indent ) Using airlift or laminar flow aeration or foam culture

394

.. (2 indent ) Wherein culture vessel is rotated or oscillated or culture is agitated

395

. (1 indent ) Solid support and method of culturing cells on said solid support

396

.. (2 indent ) Support is a resin

397

.. (2 indent ) Support is a gel surface

398

.. (2 indent ) Support is a fiber

399

... (3 indent ) Fabric, mat, gauze, or fibrous coating

400

... (3 indent ) Hollow

401

.. (2 indent ) Support is a membrane

402

.. (2 indent ) Support is a coated or treated surface

403

.. (2 indent ) Support is a suspendable particle

404

. (1 indent ) Culture medium, per se

405

.. (2 indent ) Contains a growth factor or growth regulator

406

... (3 indent ) Contains a polypeptide hormone

407

.. (2 indent ) Contains an albumin

408

.. (2 indent ) Contains an animal extract

410

PLANT CELL OR CELL LINE, PER SE (E.G., TRANSGENIC, MUTANT, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING, OR PRESERVING PLANT CELL OR CELL LINE; PROCESS OF ISOLATING OR SEPARATING A PLANT CELL OR CELL LINE; PROCESS OF REGENERATING PLANT CELLS INTO TISSUE, PLANT PART, OR PLANT, PER SE, WHERE NO GENOTYPIC CHANGE OCCURS; MEDIUM THEREFORE

411

. (1 indent ) Tomato cell or cell line, per se

412

. (1 indent ) Corn cell or cell line, per se

413

.. (2 indent ) Herbicide resistant

414

. (1 indent ) Tobacco cell or cell line, per se

415

. (1 indent ) Soybean cell or cell line, per se

416

. (1 indent ) Sunflower cell or cell line, per se

417

. (1 indent ) Potato cell or cell line, per se

418

. (1 indent ) Plant cell or cell line, per se, is pest or herbicide resistant or pest lethal

419

. (1 indent ) Plant cell or cell line, per se, contains exogenous or foreign nucleic acid

420

. (1 indent ) Culture, maintenance, or preservation techniques, per se

421

.. (2 indent ) Involving protoplast

422

.. (2 indent ) Involving conifer cell or tissue (e.g., pine, spruce, fir, cedar, etc.)

423

.. (2 indent ) Involving tomato cell or tissue

424

.. (2 indent ) Involving corn cell or tissue

425

.. (2 indent ) Involving tobacco cell or tissue

426

.. (2 indent ) Involving soybean cell or tissue

427

.. (2 indent ) Involving cotton cell or tissue

428

.. (2 indent ) Involving sunflower cell or tissue

429

.. (2 indent ) Involving potato cell or tissue

430

.. (2 indent ) Involving regeneration or propagation into a plant or plant part

430.1

... (3 indent ) Involving callus or embryonic stage

431

. (1 indent ) Medium, per se, for culture, maintenance, regeneration, etc.

242

SPORE FORMING OR ISOLATING PROCESS

243

MICRO-ORGANISM, PER SE (E.G., PROTOZOA, ETC.); COMPOSITIONS THEREOF; PROCES OF PROPAGATING, MAINTAINING OR PRESERVING MICRO-ORGANISMS OR COMPOSITIONS THEREOF; PROCESS OF PREPARING OR ISOLATING A COMPOSITION CONTAINING A MICRO-ORGANISM; CULTURE MEDIA THEREFOR

244

. (1 indent ) Chemical stimulation of growth or activity by addition of chemical compound which is not an essential growth factor; stimulation of growth by removal of a chemical compound

245

. (1 indent ) Adaptation or attenuation of cells

246

. (1 indent ) Foam culture

247

. (1 indent ) Utilizing media containing lower alkanol (i.e., having one to six carbon atoms)

248

. (1 indent ) Utilizing media containing hydrocarbon

249

.. (2 indent ) Aliphatic

250

... (3 indent ) Having five or less carbon atoms

251

. (1 indent ) Utilizing media containing waste sulphite liquor

252

. (1 indent ) Utilizing media containing cellulose or hydrolysates thereof

252.1

. (1 indent ) Bacteria or actinomycetales; media therefor

252.2

.. (2 indent ) Rhizobium or agrobacterium

252.3

.. (2 indent ) Transformants (e.g., recombinant DNA or vector or foreign or exogenous gene containing, fused bacteria, etc.)

252.31

... (3 indent ) Bacillus (e.g., B. subtilis, B. thuringiensis, etc.)

252.32

... (3 indent ) Brevibacterium or corynebacterium

252.33

... (3 indent ) Escherichia (e.g., E. coli, etc.)

252.34

... (3 indent ) Pseudomonas

252.35

... (3 indent ) Streptomyces

252.4

.. (2 indent ) Mixed culture

252.5

.. (2 indent ) Bacillus (e.g., B. subtilis, B. thuringiensis, etc.)

252.6

.. (2 indent ) Actinoplanes

252.7

.. (2 indent ) Clostridium

252.8

.. (2 indent ) Escherichia (e.g., E. coli, etc.) or salmonella

252.9

.. (2 indent ) Lactobacillus, pediococcus, or leuconostoc

253.1

.. (2 indent ) Mycobacterium

253.2

.. (2 indent ) Nocardia

253.3

.. (2 indent ) Pseudomonas

253.4

.. (2 indent ) Streptococcus

253.5

.. (2 indent ) Streptomyces

253.6

.. (2 indent ) Culture media, per se

254.1

. (1 indent ) Fungi

254.11

.. (2 indent ) Transformants

254.2

... (3 indent ) Yeast; media therefor

254.21

.... (4 indent ) Saccharomyces

254.22

.... (4 indent ) Candida

254.23

.... (4 indent ) Pichia

254.3

... (3 indent ) Aspergillus

254.4

... (3 indent ) Neurospora

254.5

... (3 indent ) Penicillium

254.6

... (3 indent ) Trichoderma

254.7

... (3 indent ) Fusarium

254.8

... (3 indent ) Mucor

254.9

... (3 indent ) Rhizopus

255.1

.. (2 indent ) Yeast

255.2

... (3 indent ) Saccharomyces

255.21

.... (4 indent ) Culture media, per se, or technique

255.3

... (3 indent ) Cryptococcus

255.4

... (3 indent ) Candida or torulopsis

255.5

... (3 indent ) Pichia

255.6

... (3 indent ) Hansenula

255.7

... (3 indent ) Culture media, per se, or technique

256.1

.. (2 indent ) Aspergillus

256.2

.. (2 indent ) Mucor

256.3

.. (2 indent ) Penicillium

256.4

.. (2 indent ) Cephalosporium or acremonium

256.5

.. (2 indent ) Fusarium

256.6

.. (2 indent ) Rhizopus

256.7

.. (2 indent ) Trichoderma

256.8

.. (2 indent ) Culture media, per se, or technique

257.1

. (1 indent ) Algae, media therefor

257.2

.. (2 indent ) Transformants

257.3

.. (2 indent ) Chlorella

257.4

.. (2 indent ) Euglena

257.5

.. (2 indent ) Scenedesmus

257.6

.. (2 indent ) Chlamydomonas

258.1

. (1 indent ) Protozoa, media therefor

258.2

.. (2 indent ) Plasmodium

258.3

.. (2 indent ) Leishmania

258.4

.. (2 indent ) Eimeria

259

. (1 indent ) Lysis of micro-organism

260

. (1 indent ) Preserving or maintaining micro-organism

261

. (1 indent ) Separation of micro-organism from culture media

320.1

VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)

262

PROCESS OF UTILIZING AN ENZYME OR MICRO-ORGANISM TO DESTROY HAZARDOUS OR TOXIC WASTE, LIBERATE, SEPARATE, OR PURIFY A PREEXISTING COMPOUND OR COMPOSITION THEREFORE; CLEANING OBJECTS OR TEXTILES

262.5

. (1 indent ) Destruction of hazardous or toxic waste

263

. (1 indent ) Textile treating

264

. (1 indent ) Cleaning using a micro-organism or enzyme

265

. (1 indent ) Depilating hides, bating, or hide treating using enzyme or micro-organism

266

. (1 indent ) Treating gas, emulsion, or foam

267

. (1 indent ) Treating animal or plant material or micro-organism

268

.. (2 indent ) Treating organ or animal secretion

269

.. (2 indent ) Treating blood fraction

270

.. (2 indent ) Removing nucleic acid from intact or disrupted cell

271

.. (2 indent ) Glyceridic oil, fat, ester-type wax, or higher fatty acid recovered or purified

272

.. (2 indent ) Proteinaceous material recovered or purified

273

... (3 indent ) Collagen or gelatin

274

.. (2 indent ) Carbohydrate material recovered or purified

275

... (3 indent ) Pectin or starch

276

... (3 indent ) Sugar (e.g., molasses treatment, etc.)

277

... (3 indent ) Cellulose (e.g., plant fibers, etc.)

278

.... (4 indent ) Producing paper pulp

279

.... (4 indent ) Hemp or flax treating

280

. (1 indent ) Resolution of optical isomers or purification of organic compounds or composition containing same

281

. (1 indent ) Petroleum oil or shale oil treating

282

.. (2 indent ) Desulfurizing

283.1

APPARATUS

284.1

. (1 indent ) Differentiated tissue (e.g., organ) perfusion or preservation apparatus

285.1

. (1 indent ) Mutation or genetic engineering apparatus

285.2

.. (2 indent ) With means for applying an electric current or charge (e.g., electrofusion, electroporation, etc.)

285.3

.. (2 indent ) Including projectile means

286.1

. (1 indent ) Including condition or time responsive control means

286.2

.. (2 indent ) Including position control

286.3

... (3 indent ) Plater, streaker, or spreader

286.4

... (3 indent ) Including liquid dispenser means

286.5

.. (2 indent ) Including liquid flow, level, or volume control

286.6

.. (2 indent ) Including gas flow or pressure control

286.7

.. (2 indent ) Including mixing or agitation control

287.1

. (1 indent ) Including measuring or testing

287.2

.. (2 indent ) Measuring or testing for antibody or nucleic acid, or measuring or testing using antibody or nucleic acid

287.3

.. (2 indent ) With sample or reagent mechanical transport means

287.4

.. (2 indent ) Sterility testing means

287.5

.. (2 indent ) Means for measuring gas pressure or gas volume of gas evolved from or consumed in an enzymatic or microbial reaction

287.6

.. (2 indent ) Including frangible means for introducing a sample or reagent

287.7

.. (2 indent ) Including bibulous or absorbent layer

287.8

... (3 indent ) Including multiple, stacked layers

287.9

.. (2 indent ) Including a coated reagent or sample layer

288.1

.. (2 indent ) Including a bottle, tube, flask, or jar

288.2

... (3 indent ) Including multiple internal compartments or baffles

288.3

.. (2 indent ) Including a dish, plate, slide, or tray

288.4

... (3 indent ) Including multiple compartments (e.g., wells, etc.)

288.5

.... (4 indent ) Including means for fluid passage between compartments (e.g., between wells, etc.)

288.6

.. (2 indent ) Including column separation means

288.7

.. (2 indent ) Including optical measuring or testing means

289.1

. (1 indent ) Bioreactor

290.1

.. (2 indent ) Composting apparatus

290.2

... (3 indent ) Including agitation means

290.3

.... (4 indent ) Compostor is rotatably mounted

290.4

... (3 indent ) Including solid or liquid transport means into or out of a compostor

291.1

.. (2 indent ) Malting or mashing apparatus

291.2

... (3 indent ) Movable floor to facilitate maintenance (e.g., cleaning)

291.3

... (3 indent ) Vertically spaced stages, levels, or floors

291.4

.... (4 indent ) Cascading

291.5

... (3 indent ) With agitator or mash turner

291.6

.... (4 indent ) With vertical axis of rotation

291.7

.... (4 indent ) With horizontal axis of rotation

291.8

....• (5 indent ) Rotating vessel

292.1

.. (2 indent ) Including means to transmit light into a bioreactor to facilitate photo- bioreaction (e.g., photosynthesis)

293.1

.. (2 indent ) Tubular or plug flow bioreactor

293.2

... (3 indent ) Radial or spiral flow bioreactor

294.1

.. (2 indent ) Vessels or trays in series

295.1

.. (2 indent ) Including a draft tube for agitation

295.2

... (3 indent ) Airlift bioreactor

295.3

... (3 indent ) Including a semi-permeable membrane or filter

296.1

.. (2 indent ) Bubble bioreactor

297.1

.. (2 indent ) Including semipermeable membrane or filter

297.2

... (3 indent ) Including perfusion means

297.3

.... (4 indent ) Including a spinning semipermeable membrane or filter

297.4

.... (4 indent ) Including hollow fiber or capillary

297.5

... (3 indent ) In combination with a dish, plate, or tray

298.1

.. (2 indent ) Cylindrical reaction tank or vessel horizontally disposed with respect to its central axis

298.2

... (3 indent ) With a rotatably mounted tank or vessel

299.1

.. (2 indent ) Including solid extended fluid contact reaction surface

299.2

... (3 indent ) Including a bottle, tube, jar, or flask

300.1

.. (2 indent ) Including off-gas trapping means

301.1

.. (2 indent ) Including foam breaking means

302.1

.. (2 indent ) Including magnetically coupled agitation means

303.1

.. (2 indent ) Incubator

303.2

... (3 indent ) Specifically adapted for an anaerobic microorganism or enzyme (e.g., anaerobe jars)

303.3

... (3 indent ) Including an agitator

304.1

.. (2 indent ) Bottle, tube, jar, or flask

304.2

... (3 indent ) Including multiple internal compartments for baffles

304.3

... (3 indent ) Flat culture flask

305.1

.. (2 indent ) Dish, plate, or tray

305.2

... (3 indent ) Multicompartmented

305.3

.... (4 indent ) Including cover seal

305.4

... (3 indent ) Including cover seal

306.1

. (1 indent ) Involving lysis of a microorganism by means other than comminution

307.1

. (1 indent ) Microorganism preservation, storage, or transport apparatus

308.1

. (1 indent ) Means for separation or recovery of a microorganism from culture media

309.1

. (1 indent ) Inoculator, streaker, or sampler

309.2

.. (2 indent ) Means for inoculation or sampling of a closed vessel

309.3

.. (2 indent ) Loop or wire streaker

309.4

.. (2 indent ) Replica plate

317.1

MISCELLANEOUS (E.G., SUBCELLULAR PARTS OF MICRO-ORGANISMS, ETC.)

	CROSS-REFERENCE ART COLLECTIONS

800

ELIMINATION OR REDUCTION OF CONTAMINATION BY UNDERSIRED FERMENTS (E.G., ASEPTIC CULTIVATION)

801

ANEROBIC CULTIVATION

802

LOGARITHMIC GROWTH PHASE

803

PHYSICAL RECOVERY METHODS (E.G., CHROMATOGRAPHY, GRINDING)

804

SINGLE CELL PROTEIN

805

TEST PAPERS

806

FERTILITY TESTS

807

GAS DETECTION APPARATUS

808

OPTICAL SENSING APPARATUS

809

INCUBATORS OR RACKS OR HOLDERS FOR CULTURE PLATES OR CONTAINERS

810

PACKAGED DEVICE OR KIT

811

INTERFERON

812

FOAM CONTROL

813

CONTINUOUS FERMENTATION

814

ENZYME SEPARATION OR PURIFICATION

815

. (1 indent ) By sorption

816

. (1 indent ) By solubility

817

ENZYME OR MICROBE ELECTRODE

818

AERATION OR OXYGEN TRANSFER TECHNIQUE

819

FERMENTATION VESSELS IN SERIES

820

SUBCELLULAR PARTS OF MICRO-ORGANISMS

821

MICRO-ORGANISMS USED IN THE DESTRUCTION OF HAZARDOUS OR TOXIC WASTE

MICRO-ORGANISM CROSS-REFERENCE ART COLLECTIONS

822

. (1 indent ) Using bacteria or actinomycetales

823

.. (2 indent ) Acetobacter

824

.. (2 indent ) Achromobacter

825

.. (2 indent ) Actinomadura

826

.. (2 indent ) Actinomyces

827

.. (2 indent ) Actinoplanes

828

.. (2 indent ) Aerobacter

829

.. (2 indent ) Alcaligenes

830

.. (2 indent ) Arthrobacter

831

.. (2 indent ) Azotobacter

832

.. (2 indent ) Bacillus

833

... (3 indent ) Bacillus brevis

834

... (3 indent ) Bacillus cereus

835

... (3 indent ) Bacillus circulans

836

... (3 indent ) Bacillus licheniformis

837

... (3 indent ) Bacillus megaterium

838

... (3 indent ) Bacillus polymyxa

839

... (3 indent ) Bacillus subtilis

840

.. (2 indent ) Brevibacterium

841

.. (2 indent ) Chainia

842

.. (2 indent ) Clostridium

843

.. (2 indent ) Corynebacterium

844

... (3 indent ) Corynebacterium diphtheriae

845

... (3 indent ) Corynebacterium poinsettiae

846

... (3 indent ) Corynebacterium pyogenes

847

.. (2 indent ) Erwinia

848

.. (2 indent ) Escherichia

849

... (3 indent ) Escherichia coli

850

.. (2 indent ) Flavobacterium

851

.. (2 indent ) Haemophilus

852

.. (2 indent ) Klebsiella

853

.. (2 indent ) Lactobacillus

854

... (3 indent ) Lactobacillus acidophilus

855

... (3 indent ) Lactobacillus brevis

856

... (3 indent ) Lactobacillus casei

857

... (3 indent ) Lactobacillus plantarum

858

.. (2 indent ) Methylomonas

859

.. (2 indent ) Micrococcus

860

... (3 indent ) Micrococcus flavus

861

... (3 indent ) Micrococcus glutamicus

862

... (3 indent ) Micrococcus lysodeikticus

863

.. (2 indent ) Mycobacterium

864

... (3 indent ) Mycobacterium avium

865

... (3 indent ) Mycobacterium fortuitum

866

... (3 indent ) Mycobacterium smegmatis

867

.. (2 indent ) Micromonospora

868

... (3 indent ) Micromonospora chalcea

869

... (3 indent ) Micromonospora purpurea

870

.. (2 indent ) Mycoplasma

871

.. (2 indent ) Neisseria

872

.. (2 indent ) Nocardia

873

.. (2 indent ) Proteus

874

.. (2 indent ) Pseudomonas

875

... (3 indent ) Pseudomonas aeruginosa

876

... (3 indent ) Pseudomonas fluorescens

877

... (3 indent ) Pseudomonas putida

878

.. (2 indent ) Rhizobium

879

.. (2 indent ) Salmonella

880

.. (2 indent ) Serratia

881

... (3 indent ) Serratia marcescens

882

.. (2 indent ) Staphylococcus

883

... (3 indent ) Staphylococcus aureus

884

... (3 indent ) Staphylococcus epidermidis

885

.. (2 indent ) Streptococcus

886

.. (2 indent ) Streptomyces

887

... (3 indent ) Streptomyces albus

888

... (3 indent ) Streptomyces antibioticus

889

... (3 indent ) Streptomyces aureofaciens

890

... (3 indent ) Streptomyces aureus

891

... (3 indent ) Streptomyces bikiniensia

892

... (3 indent ) Streptomyces candidus

893

... (3 indent ) Streptomyces chartreusis

894

... (3 indent ) Streptomyces diastatochromogenes

895

... (3 indent ) Streptomyces filipinensis

896

... (3 indent ) Streptomyces fradiae

897

... (3 indent ) Streptomyces griseus

898

... (3 indent ) Streptomyces hygroscopicus

899

... (3 indent ) Streptomyces lavendulae

900

... (3 indent ) Streptomyces lincolnensis

901

... (3 indent ) Streptomyces noursei

902

... (3 indent ) Streptomyces olivaceus

903

... (3 indent ) Streptomyces platensis

904

... (3 indent ) Streptomyces rimosus

905

... (3 indent ) Streptomyces sparogenes

906

... (3 indent ) Streptomyces venezuelae

907

.. (2 indent ) Streptosporangium

908

.. (2 indent ) Streptovirticillium

909

.. (2 indent ) Vibrio

910

.. (2 indent ) Xanthomonas

911

. (1 indent ) Using fungi

912

.. (2 indent ) Absidia

913

.. (2 indent ) Aspergillus

914

... (3 indent ) Aspergillus awamori

915

... (3 indent ) Aspergillus flavus

916

... (3 indent ) Aspergillus fumigatus

917

... (3 indent ) Aspergillus niger

918

... (3 indent ) Aspergillus oryzae

919

... (3 indent ) Aspergillus ustus

920

... (3 indent ) Aspergillus wenti

921

.. (2 indent ) Candida

922

... (3 indent ) Candida albicans

923

... (3 indent ) Candida lipolytica

924

... (3 indent ) Candida tropicalis

925

.. (2 indent ) Cephalosporium

926

... (3 indent ) Cephalosporium acremonium

927

... (3 indent ) Cephalosporium caerulens

928

... (3 indent ) Cephalosporium crotocinigenium

929

.. (2 indent ) Fusarium

930

.. (2 indent ) Hansenula

931

.. (2 indent ) Mucor

932

.. (2 indent ) Paecilomyces

933

.. (2 indent ) Penicillium

934

... (3 indent ) Penicillium brevi

935

... (3 indent ) Penicillium chrysogenum

936

... (3 indent ) Penicillium notatium

937

... (3 indent ) Penicillium patulum

938

.. (2 indent ) Pichia

939

.. (2 indent ) Rhizopus

940

.. (2 indent ) Saccharomyces

941

... (3 indent ) Saccharomyces carlsbergensis

942

... (3 indent ) Saccharomyces cerevisiae

943

... (3 indent ) Saccharomyces lactis

944

.. (2 indent ) Torulopsis

945

.. (2 indent ) Trichoderma

946

. (1 indent ) Using algae

947

. (1 indent ) Using protozoa

948

. (1 indent ) Using viruses or cell lines

	CROSS-REFERENCE ART COLLECTIONS

RELATED TO SUBCLASSES

7.1 THROUGH 7.95

960

IMMUNOHISTOCHEMICAL ASSAY

961

INCLUDING A STEP OF FORMING, RELEASING, OR EXPOSING THE ANTIGEN OR FORMING THE HAPTEN-IMMUNOGENIC CARRIER COMPLEX OR THE ANTIGEN, PER SE

962

PREVENTION OR REMOVAL OF INTERFERING MATERIALS OR REACTANTS OR OTHER TREATMENT TO ENHANCE RESULTS (E.G., DETERMINING OR PREVENTING NONSPECIFIC BINDING, ETC.)

963

METHODS OF STOPPING AN ENZYME REACTION OR STABILIZING THE TEST MATERIALS

964

INCLUDING ENZYME-LIGAND CONJUGATE PRODUCTION (E.G., REDUCING RATE OF NONPRODUCTIVE LINKAGE, ETC.)

965

INVOLVING IDIOTYPE OR ANTI-IDIOTYPE ANTIBODY

966

INVOLVING AN ENZYME SYSTEM WITH HIGH TURNOVER RATE OR COMPLEMENT MAGNIFIED ASSAY (E.G., MULTI-ENZYME SYSTEMS, ETC.)

967

STANDARDS, CONTROLS, MATERIALS (E.G., VALIDATION STUDIES, BUFFER SYSTEMS, ETC.)

968

HIGH ENERGY SUBSTRATES (E.G., FLUORESCENT, CHEMILUMINESCENT, RADIOACTIVE, ETC.)

969

MULTIPLE LAYERING OF REACTANTS

970

TEST STRIP OR TEST SLIDE

971

CAPTURE OF COMPLEX AFTER ANTIGEN-ANTIBODY REACTION

972

MODIFIED ANTIBODY (E.G., HYBRID, BIFUNCTIONAL, ETC.)

973

SIMULTANEOUS DETERMINATION OF MORE THAN ONE ANALYTE

974

AIDS RELATED TEST

975

KIT

	FOREIGN ART COLLECTIONS

FOR000

CLASS-RELATED FOREIGN DOCUMENTS

Any foreign patents or non-patent literature from subclasses that have been reclassified have been transferred directly to FOR Collections listed below. These Collections contain ONLY foreign patents or non-patent literature. The parenthetical references in the Collection titles refer to the abolished subclasses from which these Collections were derived.

FOR100

ANIMAL OR PLANT CELL (E.G., CELL LINES, ETC.); COMPOSITIONS THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING ANIMAL OR PLANT CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL OR PLANT CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING ANIMAL OR PLANT CELL; CULTURE MEDIA THEREFORE (435/240.1)

FOR101

. (1 indent ) Animal cells, per se, culture techniques and media (435/240.2)

FOR102

.. (2 indent ) Techniques of establishing a primary culture (435/240.21)

FOR103

.. (2 indent ) Culture of encapsulated cells (435/240.22)

FOR104

.. (2 indent ) Culture of cells on solid support (e.g., anchorage dependent cells) (435/240.23)

FOR105

... (3 indent ) Support is suspendable particle (435.240.24)

FOR106

... (3 indent ) Culture of cells on membrane (435/240.241)

FOR107

.... (4 indent ) Hollow fiber membrane (435/240.242)

FOR108

... (3 indent ) Solid support treated or coated to enhance attachment or growth (435/240.243)

FOR109

.. (2 indent ) Culture in suspension (435/240.25)

FOR110

.. (2 indent ) Fused or hybrid cells (435/240.26)

FOR111

... (3 indent ) Ab or Ig fragments producing cells (435/240.27)

FOR112

.. (2 indent ) Culture medium, per se (435/240.3)

FOR113

... (3 indent ) Defined medium (435/240.31)

FOR114

. (1 indent ) Plant cells, per se, culture techniques and media (435/240.4)

FOR115

.. (2 indent ) Culture techniques (e.g., meristem culture, etc.) (435/240.45)

FOR116

... (3 indent ) Culture in suspension (435/240.46)

FOR117

.... (4 indent ) Protoplasts (435/240.47)

FOR118

... (3 indent ) Callus culture (435/240.48)

FOR119

.... (4 indent ) Regeneration (includes nonflowering ornamentals (435/240.49)

FOR120

....• (5 indent ) Agronomic crops (e.g., tobacco, grains, etc.) (435/240.5)

FOR121

....• (5 indent ) Fruit and vegetable crops (e.g., tomato, etc.) (435/240.51)

FOR122

.. (2 indent ) Culture medium, per se, or regeneration medium, per se (435/240.54)

FOR123

MUTATION OR GENETIC ENGINEERING (435/172.1)

FOR124

. (1 indent ) Fused or hybrid cell formation (435/172.2)

FOR125

. (1 indent ) Recombination (435/172.3)

FOR126

OBTAINING THE DESIRED GENE; DNA, RNA PER SE AND THE MODIFICATION THEREOF OTHER THAN VECTOR MODIFICATION (935/1)

FOR127

. (1 indent ) DNA-RNA hybrid (935/2)

FOR128

. (1 indent ) RNA (935/3)

FOR129

.. (2 indent ) mRNA (935/4)

FOR130

.. (2 indent ) 2-100 nucleotides in length, e.g., t-RNA, etc. (935/5)

FOR131

. (1 indent ) DNA, e.g., regulatory sequences, etc. (935/6)

FOR132

.. (2 indent ) Homopolymeric, e.g., poly d(A) sequence, etc. (935/7)

FOR133

.. (2 indent ) 12-75 nucleotides in length, e.g., primers, etc. (935/8)

FOR134

.. (2 indent ) Structural gene sequence (935/9)

FOR135

... (3 indent ) Modified structural gene, e.g., nonnaturally occurring sequence, etc. (935/10)

FOR136

... (3 indent ) Polypeptide (935/11)

FOR137

.... (4 indent ) Antigenic material (935/12)

FOR138

.... (4 indent ) Hormone, e.g., human growth factor, insulin, etc. (935/13)

FOR139

.... (4 indent ) Enzyme (935/14)

FOR140

.... (4 indent ) Antibody (935/15)

FOR141

. (1 indent ) Methods of producing DNA or RNA other than by expression vectors, e.g., culture of cells high in DNA, etc. (935/16)

FOR142

.. (2 indent ) Cell free production (935/17)

FOR143

... (3 indent ) cDNA synthesis (935/18)

FOR144

. (1 indent ) Isolation or purification of DNA or RNA (935/19)

FOR145

.. (2 indent ) RNA (935/20)

FOR146

... (3 indent ) mRNA (935/21)

FOR147

VECTORS AND METHODS OF MODIFYING VECTORS (935/22)

FOR148

. (1 indent ) Inserting gene into vector to form recombinant vector, i.e., cleavage and ligation (935/23)

FOR149

.. (2 indent ) Vector utilized, e.g., episomes, etc. (935/24)

FOR150

... (3 indent ) Plant virus (935/25)

FOR151

... (3 indent ) Cosmid (935/26)

FOR152

... (3 indent ) Plasmid (935/27)

FOR153

.... (4 indent ) Yeast (935/28)

FOR154

.... (4 indent ) Prokaryotic (935/29)

FOR155

.... (4 indent ) Plant (935/30)

FOR156

... (3 indent ) Bacteriophage (935/31)

FOR157

... (3 indent ) Animal virus, e.g., SV40, etc. (935/32)

FOR158

METHODS OF ENHANCING OR DIMINISHING EXPRESSION (935/33)

FOR159

. (1 indent ) Eukaryotic cell (935/34)

FOR160

.. (2 indent ) Plant cell (935/35)

FOR161

.. (2 indent ) Transcription (935/36)

FOR162

.. (2 indent ) Yeast cell (935/37)

FOR163

. (1 indent ) Prokaryotic cell (935/38)

FOR164

.. (2 indent ) Transcription (935/39)

FOR165

... (3 indent ) Operon selection (935/40)

FOR166

.... (4 indent ) Promoter, e.g., portable promoters, etc. (935/41)

FOR167

.. (2 indent ) Gene dosage modification, e.g., copy number amplification, etc. (935/42)

FOR168

... (3 indent ) Inducible, e.g., temperature inducible, etc. (935/43)

FOR169

.. (2 indent ) Translation (935/44)

FOR170

... (3 indent ) Ribosome binding site (935/45)

FOR171

... (3 indent ) Initiation (935/46)

FOR172

. (1 indent ) Fused protein or peptide (435/47)

FOR173

.. (2 indent ) Signal peptide, e.g., secretion, etc. (935/48)

FOR174

. (1 indent ) Post translational modification (935/49)

FOR175

.. (2 indent ) Glycosylation (935/50)

FOR176

.. (2 indent ) Peptide bond cleavage (935/51)

FOR177

METHODS OF INTRODUCING GENE INTO HOST CELL, E.G., TRANSFORMATION OR TRANSFECTION, ETC. (935/52)

FOR178

. (1 indent ) Microinjection (935/53)

FOR179

. (1 indent ) Microencapsulation, e.g., liposome vesicle, etc. (935/54)

FOR180

. (1 indent ) Using vector, e.g., plasmid, etc. (935/55)

FOR181

.. (2 indent ) Plasmid (935/56)

FOR182

.. (2 indent ) Virus (935/57)

FOR183

... (3 indent ) Phage, e.g., phage lambda, etc. (935/58)

FOR184

METHOD OF USE OF GENETICALLY ENGINEERED CELLS, E.G., OIL SPILL CLEANUP, ETC. (935/59)

FOR185

. (1 indent ) To produce an identified chemical product, e.g., amino acid, etc. (935/60)

FOR186

.. (2 indent ) Yield optimization (935/61)

FOR187

. (1 indent ) Control of genetic diseases or defects by use of added gene, e.g., gene therapy (935/62)

FOR188

. (1 indent ) Use in animal husbandry (935/63)

FOR189

. (1 indent ) Use in agriculture (935/64)

FOR190

. (1 indent ) Vaccine production (935/65)

FOR191

CELLS CONTAINING A VECTOR AND/OR EXOGENOUS GENE, PER SE; PROPAGATION THEREOF; OTHER MEMBRANE ENCAPSULATED DNA, E.G., PROTOPLASTS, ETC. (935/66)

FOR192

. (1 indent ) Plant cells (935/67)

FOR193

. (1 indent ) Fungal cells (935/68)

FOR194

.. (2 indent ) Yeast cells (935/69)

FOR195

. (1 indent ) Animal cell (935/70)

FOR196

.. (2 indent ) Human cell (935/71)

FOR197

. (1 indent ) Bacteria (935/72)

FOR198

.. (2 indent ) Escherichia (935/73)

FOR199

.. (2 indent ) Bacillus (935/74)

FOR200

.. (2 indent ) Streptomyces (935/75)

FOR201

ASSAY RELATED TO GENETIC ENGINEERING (935/76)

FOR202

. (1 indent ) Methods of analysis of nucleic acids (935/77)

FOR203

.. (2 indent ) Including hybridization (935/78)

FOR204

. (1 indent ) Methods of selection of recombinant gene containing vector; materials therefore, e.g., replica plating, etc. (935/79)

FOR205

.. (2 indent ) Gene library manipulation (935/80)

FOR206

.. (2 indent ) Antigen-antibody (935/81)

FOR207

.. (2 indent ) Enzyme activity (935/82)

FOR208

.. (2 indent ) Host suicide (935/83)

FOR209

.. (2 indent ) Selection medium (935/84)

FOR210

GENETIC ENGINEERING APPARATUS (935/85)

FOR211

. (1 indent ) Analytical, e.g., for autoradiography, etc. (935/86)

FOR212

.. (2 indent ) Automated (935/87)

FOR213

. (1 indent ) Synthesis, e.g., peptide or gene synthesizers, etc. (935/88)

FOR214

HYBRID OR FUSED CELL TECHNOLOGY, METHODS OF IMMORTALIZING CELLS, E.G., HYBRIDOMA, ETC. (935/89)

FOR215

. (1 indent ) Method of selection of the desired cell (935/90)

FOR216

.. (2 indent ) Of plant cells, e.g., protoplasts, etc. (935/91)

FOR217

.. (2 indent ) Using positive selection technique (935/92)

FOR218

. (1 indent ) Method of production of hybrid or fused cells, e.g., chromosome or genome transfer techniques, etc. (935/93)

FOR219

.. (2 indent ) Of plant cells (935/94)

FOR220

. (1 indent ) Fused or hybrid cell, per se (935/95)

FOR221

.. (2 indent ) Interspecies fusion (935/96)

FOR222

.. (2 indent ) Fungi, e.g., yeasts, etc. (935/97)

FOR223

.. (2 indent ) Plant cells (935/98)

FOR224

.. (2 indent ) Human cell 935/99)

FOR225

... (3 indent ) B lymphocyte (935/100)

FOR226

... (3 indent ) T lymphocyte (935/101)

FOR227

.. (2 indent ) Animal cell (935/102)

FOR228

... (3 indent ) Murine cell, e.g., mouse cell, etc. (935/103)

FOR229

.... (4 indent ) B lymphocyte (935/104)

FOR230

.... (4 indent ) T lymphocyte (935/105)

FOR231

. (1 indent ) Method of use of the fused or hybrid cell or the product thereof (935/106)

FOR232

.. (2 indent ) In vivo use of product

FOR233

.. (2 indent ) In vitro, e.g., cell cultivation techniques, affinity chromatography, etc. (935/108)

FOR234

... (3 indent ) Production of non-antibody product (935/109)

FOR235

... (3 indent ) For use as testing material (935/110)

FOR236

MISCELLANEOUS (935/111)

	DIGESTS

DIG1

COMBINATORIAL CHEMISTRY AND LIBRARY TECHNOLOGY

DIG2

. (1 indent ) Method of screening a library

DIG3

.. (2 indent ) Involving a biologically replicable entity (e.g., genetic package, vector, etc.) which is the library, displays the library, contains the library or presents the library

DIG4

... (3 indent ) The entity is a virus or bacteriophage

DIG5

... (3 indent ) The entity is a microorganism, animal cell or plant cell

DIG6

.... (4 indent ) Animal cell

DIG7

.... (4 indent ) Yeast or fungus

DIG8

.... (4 indent ) Bacteria or protozoa

DIG9

.. (2 indent ) Screening a library of inorganic compounds or materials

DIG10

... (3 indent ) Screening for catalytic activity

DIG11

... (3 indent ) The compound or material is metal containing

DIG12

.... (4 indent ) Alloy

DIG13

.... (4 indent ) Metal oxide

DIG14

.. (2 indent ) Screening a library of organic compounds or materials

DIG15

... (3 indent ) The compound or material is a peptide or a polypeptide or derivative thereof

DIG16

.... (4 indent ) Peptide nucleic acid (i.e., PNA)

DIG17

... (3 indent ) The compound or material is a nucleotide or a polynucleotide or derivative thereof

DIG18

... (3 indent ) The compound or material is a carbohydrate or derivative thereof

DIG19

... (3 indent ) The compound or material is a polymer

DIG20

.. (2 indent ) Virtual/computer based screening method (e.g., using crystallographic coordinates of a target, etc.)

DIG21

.. (2 indent ) Using deconvolution (e.g., tagging or encoding methodology, etc.)

DIG22

. (1 indent ) Library or combinatorial chemistry related product

DIG23

.. (2 indent ) Library of biologically replicable entities (e.g., genetic packages, vectors, etc.) or a biologically replicable entity (e.g., genetic packages, vectors, etc.) displaying, containing or presenting the library elements

DIG24

... (3 indent ) The entity is a virus or bacteriophage

DIG25

... (3 indent ) The entity is a microorganism, animal cell or plant cell

DIG26

.... (4 indent ) Animal cell

DIG27

.... (4 indent ) Yeast or fungus

DIG28

.... (4 indent ) Bacteria or protozoa

DIG29

.. (2 indent ) Library of inorganic compounds or materials

DIG30

... (3 indent ) The compound or material is a catalyst

DIG31

... (3 indent ) The compound or material is metal containing

DIG32

.... (4 indent ) Alloy

DIG33

.... (4 indent ) Metal oxide

DIG34

.. (2 indent ) Library of organic compounds or materials

DIG35

... (3 indent ) The compound or material is a peptide or a polypeptide or derivative thereof

DIG36

.... (4 indent ) Peptide nucleic acid (i.e., PNA)

DIG37

... (3 indent ) The compound or material is a nucleotide or a polynucleotide or derivative thereof

DIG38

... (3 indent ) The compound or material is a carbohydrate or derivative thereof

DIG39

... (3 indent ) The compound or material is a polymer

DIG40

.. (2 indent ) Support

DIG41

.. (2 indent ) Tagging, encoding or labeling agent or material (e.g., microchip transponders, etc.)

DIG42

.. (2 indent ) Linking agent for connecting support to library element

DIG43

. (1 indent ) Apparatus

DIG44

.. (2 indent ) For preparing libraries

DIG45

.. (2 indent ) For screening

DIG46

. (1 indent ) Method of making a library

DIG47

.. (2 indent ) Using biological means (e.g., using enzyme, microorganism, cell, cellular genetic component, etc.)

DIG48

.. (2 indent ) Wherein library members are bound to a soluble support

DIG49

.. (2 indent ) Wherein library members are bound to a solid support

DIG50

.. (2 indent ) Employing solution phase synthesis not utilizing a support

DIG51

.. (2 indent ) Virtual method of making, designing or optimizing a library