US 9,813,608 B2
Fast auto-focus in imaging
Michael Zahniser, Jamaica Plain, MA (US)
Assigned to Roche Diagnostics Hematology, Inc., Westborough, MA (US)
Filed by Roche Diagnostics Hematology, Inc., Westborough, MA (US)
Filed on May 22, 2015, as Appl. No. 14/719,841.
Application 14/719,841 is a continuation of application No. 13/019,118, filed on Feb. 1, 2011, granted, now 9,041,791.
Prior Publication US 2015/0256739 A1, Sep. 10, 2015
Int. Cl. H04N 9/47 (2006.01); H04N 5/232 (2006.01); G02B 21/24 (2006.01)
CPC H04N 5/23212 (2013.01) [G02B 21/244 (2013.01); G06T 2207/10148 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A method for automatically focusing multiple images of one or more objects on a substrate, the method comprising:
a) obtaining, by a processor, a representative focal distance for a first location on the substrate based on a set of focal distances at known locations on the substrate, wherein the representative focal distance is estimated as a weighted average of at least two focal distances from the set of focal distances at known locations, wherein a weight for a given focal distance is calculated based on a distance of the corresponding location from the first location;
b) acquiring, by an image acquisition device, a set of images of the first location based on the representative focal distance;
c) estimating, by a processor, an ideal focal distance corresponding to the first location based on the acquired set of images; and
d) storing the estimated ideal focal distance and the first location in the set of focal distances at known locations.