US 9,810,698 B2
Neural proteins as biomarkers for nervous system injury and other neural disorders
Kevin Ka-Wang Wang, Gainesville, FL (US); Monika Oli, Gainesville, FL (US); and Ming-Cheng Liu, Gainesville, FL (US)
Assigned to UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED, Gainesville, FL (US); and BANYAN BIOMARKERS, INC., San Diego, CA (US)
Filed by UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., Gainesville, FL (US); and BANYAN BIOMARKERS, INC., San Diego, CA (US)
Filed on Nov. 1, 2016, as Appl. No. 15/340,002.
Application 12/137,194 is a division of application No. 11/107,248, filed on Apr. 15, 2005, granted, now 7,396,654, issued on Jul. 8, 2008.
Application 15/340,002 is a continuation of application No. 12/950,142, filed on Nov. 19, 2010.
Application 12/950,142 is a continuation of application No. 12/822,560, filed on Jun. 24, 2010, granted, now 8,492,107, issued on Jul. 23, 2013.
Application 12/822,560 is a continuation in part of application No. 12/137,194, filed on Jun. 11, 2008, abandoned.
Claims priority of provisional application 60/562,944, filed on Apr. 15, 2004.
Prior Publication US 2017/0045534 A1, Feb. 16, 2017
Int. Cl. G01N 33/68 (2006.01); C07K 16/18 (2006.01); C12Q 1/68 (2006.01)
CPC G01N 33/6896 (2013.01) [C07K 16/18 (2013.01); C12Q 1/6883 (2013.01); G01N 2800/28 (2013.01); G01N 2800/52 (2013.01)] 5 Claims
 
1. A method for detecting Glial Fibrillary Acidic Protein (GFAP), comprising:
detecting whether GFAP is present in a biological sample collected from a subject suspected of having a concussion by contacting the biological sample with an anti-GFAP antibody and detecting binding of the antibody to GFAP, wherein said biological sample is a blood, blood plasma, or serum sample, wherein the subject is not suspected of having an expanding hematoma, a subarachnoid hemorrhage, a cerebral edema, raised intracranial pressure (ICP), or cerebral hypoxia.