US 9,810,658 B2
Method for the detection and quantification of analytes using three-dimensional paper-based devices
Richard M. Crooks, College Station, TX (US); Hong Liu, Nanjing (CN); Karen Scida, Austin, TX (US); and Christophe Renault, Austin, TX (US)
Assigned to Board of Regents, The University of Texas System, Austin, TX (US)
Filed by Board of Regents, The University of Texas System, Austin, TX (US)
Filed on Apr. 18, 2013, as Appl. No. 13/865,352.
Claims priority of provisional application 61/635,081, filed on Apr. 18, 2012.
Claims priority of provisional application 61/641,880, filed on May 2, 2012.
Claims priority of provisional application 61/756,772, filed on Jan. 25, 2013.
Prior Publication US 2015/0355132 A1, Dec. 10, 2015
Int. Cl. B01L 3/00 (2006.01); G01N 27/327 (2006.01); G01N 33/543 (2006.01); C12Q 1/00 (2006.01); C12Q 1/68 (2006.01); G01N 35/00 (2006.01); G01N 33/487 (2006.01)
CPC G01N 27/3276 (2013.01) [B01L 3/5023 (2013.01); B01L 3/50273 (2013.01); B01L 3/502707 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); C12Q 1/001 (2013.01); C12Q 1/6813 (2013.01); G01N 33/5438 (2013.01); G01N 33/54373 (2013.01); B01L 3/5055 (2013.01); B01L 2200/12 (2013.01); B01L 2300/045 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/126 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/065 (2013.01); G01N 33/48707 (2013.01); G01N 2035/00158 (2013.01); Y10T 29/49984 (2015.01)] 19 Claims
OG exemplary drawing
 
1. A fluidic analytical device comprising:
a support layer, wherein the support layer comprises a single sheet of material capable of transporting a liquid using capillary action; and
a plurality of channel walls formed on the support layer, wherein the channel walls define channels on the support layer, wherein a fluid added to the support layer in one or more of the channels is conducted through the channels by capillary action.