|US 9,810,656 B2|
|Electrode and use thereof|
|Jason Davis, Oxford (GB); and Paulo Roberto Bueno, Sao Paulo (BR)|
|Assigned to Oxford University Innovation Limited, Oxford, Oxfordshire (GB); and Universidade Estadual Paulista “Julio de Mesquita Filho”, Centro, Sao Paulo (BR)|
|Appl. No. 14/398,208
|Filed by Oxford University Innovation Limited, Oxford, Oxfordshire (GB); and Universidade Estadual Paulista “Julio de Mesquita Filho”, Centro, Sao Paulo (BR)|
|PCT Filed May 1, 2013, PCT No. PCT/GB2013/051121
§ 371(c)(1), (2) Date Oct. 31, 2014,
PCT Pub. No. WO2013/164611, PCT Pub. Date Nov. 7, 2013.
|Claims priority of application No. 1207585.9 (GB), filed on May 1, 2012.|
|Prior Publication US 2015/0122669 A1, May 7, 2015|
|Int. Cl. G01N 27/327 (2006.01); G01N 33/543 (2006.01)|
|CPC G01N 27/327 (2013.01) [G01N 27/3276 (2013.01); G01N 33/5438 (2013.01); G01N 2333/4737 (2013.01)]||17 Claims|
|1. An electrode for use in the electrochemical detection of a target species, the electrode comprising:
a planar surface having probe molecules disposed thereon, in which the probe molecules are capable of electrochemically detecting a target species comprising C reactive protein by binding selectively to the target species, wherein the electrode, prior to binding of the probe molecules with the target species, has an electron transfer resistance per area of the electrode of from 10 megaohms cm−2 to 95 megaohms cm−2.