US 9,810,638 B2
System and method for optical detection using capillary action
Arman Ghodousi, Alexandria, VA (US); Sarah Josepha Toal, Gaithersburg, MD (US); Gregory Scott Ericksen, Silver Spring, MD (US); Daniel Douglas Montgomery, Washington, DC (US); Thomas Emory McVeigh, Shenandoah Junction, WV (US); Jacek Kotowicz, Washington, DC (US); and Sean Conte, Gaithersburg, MD (US)
Assigned to REDXDEFENSE, LLC, Rockville, MD (US)
Filed by RedXDefense, LLC, Rockville, MD (US)
Filed on Jun. 6, 2014, as Appl. No. 14/298,639.
Application 14/298,639 is a continuation in part of application No. PCT/US2013/035121, filed on Apr. 3, 2013.
Claims priority of provisional application 61/619,674, filed on Apr. 3, 2012.
Claims priority of provisional application 61/718,345, filed on Oct. 25, 2012.
Prior Publication US 2014/0287520 A1, Sep. 25, 2014
Int. Cl. G01N 21/00 (2006.01); G01N 21/78 (2006.01); G01N 21/84 (2006.01); G01N 33/22 (2006.01); G01N 15/06 (2006.01); G01N 15/00 (2006.01)
CPC G01N 21/78 (2013.01) [G01N 15/0612 (2013.01); G01N 21/8483 (2013.01); G01N 33/22 (2013.01); G01N 2015/0096 (2013.01); G01N 2015/0693 (2013.01); G01N 2201/062 (2013.01)] 29 Claims
OG exemplary drawing
1. A method of detecting an analyte comprising:
collecting a sample on a sample card by wiping the sample with the sample card, said sample card containing a sample substrate, an absorbent pad and at least one test capsule containing a liquid, wherein at least one of the sample substrate, the absorbent pad and the at least one test capsule contains detection reagents;
coupling the sample card to a card carrier of a reader device;
performing a detection cycle including: releasing the liquid of the at least one test capsule, whereby the liquid dissolves the detection reagents contained in the sample card and delivers said reagents to the sample, causing a chemical reaction between the sample and the detection reagents to occur; and assessing an optical signal produced by the chemical reaction of the sample and the detection reagents in establishing a test result; and
analyzing the sample using a second device that is distinct from the reader device.