US 9,810,607 B2
Microfluidic device
Christoph Merten, Heidelberg (DE); and Ramesh Utharala, Miryalaguda (IN)
Assigned to EMBL, Heidelberg (DE)
Appl. No. 14/344,478
Filed by Christoph Merten, Heidelberg (DE); and Ramesh Utharala, Miryalaguda (IN)
PCT Filed Sep. 14, 2012, PCT No. PCT/EP2012/068117
§ 371(c)(1), (2), (4) Date May 1, 2014,
PCT Pub. No. WO2013/037962, PCT Pub. Date Mar. 21, 2013.
Claims priority of application No. 1115895.3 (GB), filed on Sep. 14, 2011.
Prior Publication US 2014/0332083 A1, Nov. 13, 2014
Int. Cl. G01N 1/28 (2006.01); B01L 3/00 (2006.01); G01J 3/46 (2006.01)
CPC G01N 1/28 (2013.01) [B01L 3/502784 (2013.01); G01J 3/46 (2013.01); B01L 2200/026 (2013.01); B01L 2200/061 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/0694 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0487 (2013.01); G01J 2003/466 (2013.01); Y10T 137/0318 (2015.04); Y10T 137/469 (2015.04); Y10T 137/877 (2015.04)] 6 Claims
OG exemplary drawing
 
1. A microfluidic apparatus for providing one or more substance liquids to a microfluidic channel network, the microfluidic apparatus comprising the microfluidic channel network, at least one first substance liquid inlet, a second substance liquid inlet, at least one first inlet valve, a second inlet valve, and at least one input device for continuously applying a substantially constant pressure or a substantially continuous flow to the at least one first substance liquid at the at least one first substance liquid inlet,
wherein the microfluidic channel network comprises a substance liquid combining area, the substance liquid combining area being connected to a droplet generation junction, and wherein the at least one first inlet valve is switchable between a first position, in which a liquid connection from the at least one first substance liquid inlet to the substance liquid combining area-is open, and a second position, in which the liquid connection from the at least one first substance liquid inlet to substance liquid combining area-is closed,
wherein the second inlet valve is switchable between a first position in which a liquid connection from the second substance liquid inlet to the substance liquid combing area microfluidic channel network is open, and a second position, in which the liquid connection from the second substance liquid inlet to substance liquid combining area the microfluidic channel network is closed.