US 9,809,856 B2
Method for predicting risk of metastasis
J. William Harbour, St. Louis, MO (US)
Assigned to WASHINGTON UNIVERSITY, St. Louis, MO (US)
Filed by The Washington University, St. Louis, MO (US)
Filed on Dec. 12, 2013, as Appl. No. 14/104,686.
Application 14/104,686 is a division of application No. 12/989,272, granted, now 8,642,279, previously published as PCT/US2009/041436, filed on Apr. 22, 2009.
Claims priority of provisional application 61/046,879, filed on Apr. 22, 2008.
Prior Publication US 2014/0141441 A1, May 22, 2014
Int. Cl. C12Q 1/68 (2006.01)
CPC C12Q 1/6886 (2013.01) [C12Q 2600/158 (2013.01)] 7 Claims
 
1. A method of detecting expression levels of nucleic acid sequences in a melanoma tumor in a subject, the method comprising contacting a tumor sample obtained from the subject with a nucleic acid array consisting of nucleic acid sequences that hybridize specifically to at least eight nucleic acid nucleic acid sequences and up to twelve nucleic acid sequences, wherein the at least eight nucleic acid nucleic acid sequences and up to twelve nucleic acid sequences include MTUS1 and at least seven sequences selected from the group of nucleic acids consisting of CDH1, ECM1, EIF1 B, FXR1, HTR2B, ID2, LMCD1, LTA4H, RAB31, ROBO1, and SATB1 and detecting the level of expression of the at least eight nucleic acid sequences and up to twelve nucleic acid sequences nucleic acid sequences in the tumor sample from the subject.