US 9,809,645 B2
Anti-Staphylococcus antibody, method for manufacturing same, and usage of same
Hiroyoshi Ohsawa, Nerima-ku (JP); Jumpei Enami, Nerima-ku (JP); and Keiichi Hiramatsu, Bunkyo-ku (JP)
Assigned to ZENYAKU KOGYO KABUSHIKIKAISHA, Bunkyo-ku (JP); and Juntendo Educational Foundation, Bunkyo-ku (JP)
Appl. No. 14/774,979
Filed by ZENYAKU KOGYO KABUSHIKIKAISHA, Bunkyo-ku (JP); and Juntendo Educational Foundation, Bunkyo-ku (JP)
PCT Filed Mar. 11, 2014, PCT No. PCT/JP2014/056324
§ 371(c)(1), (2) Date Sep. 11, 2015,
PCT Pub. No. WO2014/142117, PCT Pub. Date Sep. 18, 2014.
Claims priority of application No. 2013-049268 (JP), filed on Mar. 12, 2013.
Prior Publication US 2016/0024190 A1, Jan. 28, 2016
Int. Cl. A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 39/38 (2006.01); C07K 16/12 (2006.01)
CPC C07K 16/1271 (2013.01) [A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/14 (2013.01); C07K 2317/33 (2013.01); C07K 2317/76 (2013.01)] 19 Claims
 
1. An antibody, comprising:
a heavy chain variable region that comprises
(i) CDRH1 of SEQ ID NO: 1, CDRH2 of SEQ ID NO: 2, and CDRH3 of SEQ ID NO: 3 or
(ii) CDRH1 of SEQ ID NO: 9, CDRH2 of SEQ ID NO: 10, and CDRH3 of SEQ ID NO: 11; and
a light chain variable region that comprises
(i) CDRL1 of SEQ ID NO: 4, CDRL2 of SEQ ID NO: 5, and CDRL3 of SEQ ID NO: 6 or
(ii) CDRL1 of SEQ ID NO: 12, CDRL2 of SEQ ID NO: 13, and CDRL3 of SEQ ID NO: 14.