US 9,809,631 B2
Targeting of podoplanin with lectin for use in the prevention and treatment of cancer
Gary S. Goldberg, Glassboro, NJ (US); and Yongquan Shen, Glassboro, NJ (US)
Filed by Rowan University, Glassboro, NJ (US)
Filed on Oct. 23, 2015, as Appl. No. 14/921,641.
Application 14/921,641 is a continuation of application No. 13/218,717, filed on Aug. 26, 2011, granted, now 9,169,327.
Application 13/218,717 is a continuation in part of application No. 12/401,849, filed on Mar. 11, 2009, granted, now 8,114,593.
Claims priority of provisional application 61/069,198, filed on Mar. 12, 2008.
Claims priority of provisional application 61/085,039, filed on Jul. 31, 2008.
Prior Publication US 2016/0207968 A1, Jul. 21, 2016
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/42 (2006.01); A61K 38/17 (2006.01); A61K 9/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01)
CPC C07K 14/42 (2013.01) [A61K 9/0053 (2013.01); A61K 38/178 (2013.01); C07K 16/28 (2013.01); C07K 16/3046 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57484 (2013.01); A61K 2039/505 (2013.01); C07K 2317/73 (2013.01); C07K 2319/30 (2013.01); C07K 2319/60 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); G01N 2333/47 (2013.01)] 24 Claims
 
1. A chimeric molecule comprising a lectin fused to at least one heterologous polypeptide selected from the group consisting of an epitope tag, an immunoglobulin, and a combination thereof, wherein the lectin comprises SEQ ID NO:23.