US 9,809,622 B2
Tumor-targeting polypeptide and application thereof
Musheng Zeng, Guangzhou (CN); Xing Zhang, Guangzhou (CN); Jun Wang, Guangzhou (CN); Guokai Feng, Guangzhou (CN); Mengqing Zhang, Guangzhou (CN); and Qian Zhong, Guangzhou (CN)
Assigned to Sun Yat-Sen University Cancer Center, Guangdong (CN)
Appl. No. 15/21,366
Filed by Sun Yat-sen University Cancer Center, Guangzhou (CN)
PCT Filed Sep. 5, 2014, PCT No. PCT/CN2014/085954
§ 371(c)(1), (2) Date Jul. 27, 2016,
PCT Pub. No. WO2015/035881, PCT Pub. Date Mar. 19, 2015.
Claims priority of application No. 2013 1 0413634 (CN), filed on Sep. 11, 2013.
Prior Publication US 2016/0355548 A1, Dec. 8, 2016
Int. Cl. A61K 38/00 (2006.01); A61K 38/03 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 51/08 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 7/00 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01)
CPC C07K 7/06 (2013.01) [A61K 47/48246 (2013.01); A61K 49/0056 (2013.01); A61K 51/08 (2013.01); A61K 51/088 (2013.01); C07K 7/08 (2013.01); A61K 38/00 (2013.01)] 8 Claims
 
1. A tumor-targeting peptide, comprising a motif having a general formula of: RWYDENA (SEQ ID NO:8),
wherein, a C-terminal, an N-terminal, or both the C and N terminals of the motif are selectively connected to 1-3 amino acids.