US 9,809,621 B2
Stable peptide-based PACE4 inhibitors
Robert Day, Sherbrooke (CA); Witold A. Neugebauer, Ottawa (CA); and Yves Dory, Cookshire (CA)
Assigned to SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C., Sherbrooke (CA)
Appl. No. 14/342,041
Filed by Robert Day, Sherbrooke (CA); Witold A. Neugebauer, Ottawa (CA); and Yves Dory, Cookshire (CA)
PCT Filed Aug. 30, 2012, PCT No. PCT/CA2012/050601
§ 371(c)(1), (2), (4) Date Mar. 18, 2014,
PCT Pub. No. WO2013/029180, PCT Pub. Date Mar. 7, 2013.
Claims priority of provisional application 61/530,478, filed on Sep. 2, 2011.
Prior Publication US 2014/0206622 A1, Jul. 24, 2014
Int. Cl. A61K 38/00 (2006.01); C07K 9/00 (2006.01); C07K 7/06 (2006.01); A61K 47/48 (2006.01); A61K 38/08 (2006.01); A61K 45/06 (2006.01)
CPC C07K 7/06 (2013.01) [A61K 38/08 (2013.01); A61K 45/06 (2013.01); A61K 47/48038 (2013.01); A61K 47/48215 (2013.01); A61K 38/00 (2013.01)] 11 Claims
 
1. A peptide sequence comprising the following formula:
[D-Leu]-LLLRVK-[AMBA].