US 9,809,592 B2
Isopropyl triazolo pyridine compounds
Chafiq Hamdouchi, Carmel, IN (US); Pranab Maiti, West Bengal (IN); and Anne Reifel Miller, Indianapolis, IN (US)
Assigned to Eli Lilly and Company, Indianapolis, IN (US)
Appl. No. 15/106,953
Filed by Eli Lilly and Company, Indianapolis, IN (US)
PCT Filed Jan. 6, 2015, PCT No. PCT/US2015/010277
§ 371(c)(1), (2) Date Jun. 21, 2016,
PCT Pub. No. WO2015/105779, PCT Pub. Date Jul. 16, 2015.
Claims priority of provisional application 61/925,797, filed on Jan. 10, 2014.
Prior Publication US 2016/0333005 A1, Nov. 17, 2016
Int. Cl. A61K 31/437 (2006.01); C07D 471/04 (2006.01)
CPC C07D 471/04 (2013.01) 17 Claims
 
1. A compound which is:

OG Complex Work Unit Drawing
wherein
R1 is selected from the group consisting of H, CH3, CN, CH2CN, C(CH3)2CN, and F;
R2 is selected from the group consisting of H, —O(C1-C3alkyl)R5, CH2CN, and CN;
R3 is selected from the group consisting of H, OCH3, CN, C(CH3)2CN, and CH2CN;
R4 is selected from the group consisting of H and CH3; and
R5 is selected from the group consisting of H, CN, C(CH3)2CN, OCH3, S(O)2CH3, and C(CH3)2OH; provided that at least one selected from the group consisting of R1, R2, R3, and R4 is H;
or a pharmaceutically acceptable salt thereof.