US 9,809,562 B2
NAT10 modulators for treating or preventing laminopathies, aging and cancer
Delphine Laurence Daniele Larrieu, Cambridge (GB); Raphaël Joël Rodriguez, Vers-Pont-du-Gard (FR); Sébastien Frédéric Stéphane Britton, Ramonville-Saint-Agne (FR); and Stephen Philip Jackson, Cambridge (GB)
Assigned to CAMBRIDGE ENTERPRISE LIMITED, Cambridge (GB); and THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris (FR)
Appl. No. 15/301,485
Filed by CAMBRIDGE ENTERPRISE LIMITED, Cambridge (GB); and THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris (FR)
PCT Filed Apr. 2, 2015, PCT No. PCT/GB2015/051040
§ 371(c)(1), (2) Date Oct. 3, 2016,
PCT Pub. No. WO2015/150824, PCT Pub. Date Oct. 8, 2015.
Claims priority of application No. 1405991.9 (GB), filed on Apr. 3, 2014.
Prior Publication US 2017/0174644 A1, Jun. 22, 2017
Int. Cl. C07D 277/50 (2006.01); A61K 31/426 (2006.01); C07D 285/16 (2006.01); A61K 31/549 (2006.01)
CPC C07D 285/16 (2013.01) [A61K 31/426 (2013.01); A61K 31/549 (2013.01); C07D 277/50 (2013.01)] 20 Claims
 
1. A compound selected from:

OG Complex Work Unit Drawing
and salts or solvates of any one thereof.