US 9,808,804 B2
Cartridges, collectors, kits, and methods for enhanced detection and quantification of analytes in collected fluid samples
Ayub Khattak, San Diego, CA (US); Clinton Sever, San Diego, CA (US); Paul Nelson, San Diego, CA (US); Ryan Cooper, San Diego, CA (US); Thomas Congdon, San Diego, CA (US); Justin Demartino, San Diego, CA (US); Raphael Shapiro, San Diego, CA (US); and Mark Duncan, San Diego, CA (US)
Assigned to CUE INC., San Diego, CA (US)
Filed by CUE INC., San Diego, CA (US)
Filed on Oct. 27, 2016, as Appl. No. 15/336,712.
Application 15/336,712 is a continuation of application No. PCT/US2016/042688, filed on Jul. 16, 2016.
Claims priority of provisional application 62/194,101, filed on Jul. 17, 2015.
Prior Publication US 2017/0043335 A1, Feb. 16, 2017
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 21/75 (2006.01); B01L 3/00 (2006.01); G01N 27/327 (2006.01); G01N 35/10 (2006.01); G01N 35/00 (2006.01); G01N 33/543 (2006.01); C12Q 1/68 (2006.01)
CPC B01L 3/508 (2013.01) [B01L 3/5023 (2013.01); B01L 3/5027 (2013.01); B01L 3/5029 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); B01L 3/523 (2013.01); G01N 27/3273 (2013.01); G01N 33/54366 (2013.01); G01N 35/0098 (2013.01); G01N 35/10 (2013.01); B01L 2200/025 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/10 (2013.01); B01L 2200/14 (2013.01); B01L 2200/16 (2013.01); B01L 2300/023 (2013.01); B01L 2300/047 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0672 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0809 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/1805 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0677 (2013.01); C12Q 1/6825 (2013.01)] 26 Claims
OG exemplary drawing
 
1. A sample analysis cartridge comprising:
an input tunnel that extends from an aperture, the input tunnel configured to permit insertion of a sample collection device having a distal portion adapted to be exposed to a fluid sample;
a reservoir configured to hold a fluid; and
a shuttle disposed in the input tunnel between the reservoir and the aperture in a first position, the shuttle comprising a body having a first end and a second end and defining a sample compartment between the first and second ends, the shuttle comprising an opening at the second end, the sample compartment configured to receive the fluid sample compressed from the distal portion of the sample collection device through the opening at the second end, the shuttle configured to move within the input tunnel when subjected to a force greater than a threshold force to a second position such that the sample compartment having the fluid sample is moved into the reservoir.