US 9,808,798 B2
Fluidic devices for biospecimen preservation
Rustem F. Ismagilov, Altadena, CA (US); Qichao Pan, Chicago, IL (US); and Stefano Begolo, Pasadena, CA (US)
Assigned to California Institute of Technology, Pasadena, CA (US)
Filed by University of Chicago, Chicago, IL (US); and California Institute of Technology, Pasadena, CA (US)
Filed on Apr. 22, 2013, as Appl. No. 13/868,009.
Claims priority of provisional application 61/636,426, filed on Apr. 20, 2012.
Prior Publication US 2013/0280725 A1, Oct. 24, 2013
Int. Cl. G01N 21/75 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 33/543 (2006.01)
CPC B01L 3/5027 (2013.01) [B01L 3/50273 (2013.01); B01L 3/502738 (2013.01); B01L 3/502715 (2013.01); B01L 3/502784 (2013.01); B01L 7/52 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0605 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/0678 (2013.01); B01L 2300/045 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0803 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0874 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/065 (2013.01); B01L 2400/0644 (2013.01); G01N 33/54366 (2013.01); Y10T 436/143333 (2015.01); Y10T 436/2525 (2015.01)] 28 Claims
OG exemplary drawing
 
1. A device for preservation or storage of a sample comprising:
(i) a first layer comprising a plurality of first chambers configured to hold the sample;
(ii) a second layer comprising one or more second chambers and comprising one or more desiccants in at least one of said one or more second chambers;
(iii) an intermediate layer disposed between said first layer and said second layer, wherein said intermediate layer comprises a porous membrane; and
wherein at least one of said plurality of first chambers configured to hold the sample, at least one of said one or more second chambers comprising one or more desiccants, and said porous membrane are configured to be connected by relative movement thereby permitting the one or more desiccants to absorb or adsorb solvent from the sample.