US 9,808,654 B2
Post procedure skin care gel and methods of use thereof
Jan Marini, San Jose, CA (US); and Subhash J. Saxena, Ringoes, NJ (US)
Assigned to JAN MARINI SKIN RESEARCH, San Jose, CA (US)
Filed by JAN MARINI SKIN RESEARCH, San Jose, CA (US)
Filed on Feb. 11, 2013, as Appl. No. 13/764,456.
Prior Publication US 2014/0228291 A1, Aug. 14, 2014
Int. Cl. A61K 8/00 (2006.01); A61K 31/74 (2006.01); A61K 38/18 (2006.01); A61Q 19/00 (2006.01); A61K 8/64 (2006.01); A61K 8/58 (2006.01); A61K 8/891 (2006.01); A61K 8/98 (2006.01); A61K 8/04 (2006.01)
CPC A61Q 19/00 (2013.01) [A61K 8/042 (2013.01); A61K 8/585 (2013.01); A61K 8/64 (2013.01); A61K 8/891 (2013.01); A61K 8/981 (2013.01)] 12 Claims
 
1. A method for post-procedure treatment following a skin resurfacing procedure, comprising:
topically applying to the skin of the subject following the skin resurfacing procedure from 1 to 100 ml. of a silicone-based gel comprising:
from 85% to 95% of the total volume cyclic dimethyl polysiloxane;
Transforming growth Factor (TGFβ1) at a concentration of from 1 to 50 μg/ml; Epidermal Growth Factor (EGF) at a concentration of from 1 to 50 μg/ml; and Basic Fibroblast Growth Factor (FGF) at a concentration of from 0.5 to 25 μg/ml;
Palmitoyl-Gly-His-Lys and SEQ ID NO: 1 Palmitoyl-Gly-Glu-Pro-Arg at a concentration of from 0.5% to 5% by weight;
in a cosmetically acceptable vehicle.