US 9,808,605 B2
Controlled porosity devices for tissue treatments, methods of use, and methods of manufacture
John E. Bacino, Landenberg, PA (US); Carey V. Campbell, Flagstaff, AZ (US); Edward H. Cully, Flagstaff, AZ (US); Benjamin M. Trapp, Flagstaff, AZ (US); and Michael J. Vonesh, Flagstaff, AZ (US)
Assigned to W. L. Gore & Associates, Inc., Newark, DE (US)
Filed by W. L. Gore & Associates, Inc., Newark, DE (US)
Filed on Oct. 3, 2012, as Appl. No. 13/644,251.
Claims priority of provisional application 61/544,170, filed on Oct. 6, 2011.
Claims priority of provisional application 61/697,262, filed on Sep. 5, 2012.
Prior Publication US 2013/0226131 A1, Aug. 29, 2013
Int. Cl. A61M 25/10 (2013.01); A61L 29/14 (2006.01); A61L 29/04 (2006.01); A61F 2/958 (2013.01)
CPC A61M 25/10 (2013.01) [A61L 29/041 (2013.01); A61L 29/146 (2013.01); A61M 25/104 (2013.01); A61F 2/958 (2013.01); A61F 2002/9583 (2013.01); A61M 25/1029 (2013.01); A61M 2025/105 (2013.01); A61M 2025/1075 (2013.01); F04C 2270/0421 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A balloon comprising:
a first porous membrane comprising a first microstructure, the first microstructure being configured to inflate to a nominal dimension in response to introduction of a fluid at an inflation pressure and an inflation rate, and resist fluid flow through the first porous membrane at pressures below a threshold perfusion pressure at which perfusion begins; and
a second porous membrane comprising a second microstructure that is different from the first microstructure, the second porous membrane being configured to withstand a hydrostatic load generated by the first membrane upon inflation,
wherein the threshold perfusion pressure is equal to or greater than the inflation pressure required to achieve the nominal dimension, and
wherein a terminal pressure, at which a maximum working pressure of the balloon is exceeded, is greater than the threshold perfusion pressure, and at the terminal pressure, a perfusion rate of the first porous membrane is about equal to or greater than the inflation rate,
wherein the perfusion rate is volume of fluid flowing through pores of the first porous membrane per unit time and the inflation rate is volume of fluid introduced into the first porous membrane per unit time.