US 9,808,539 B2
Hypoosmotic solutions for lymph node detection
Andrew P. Shawcross, Cambridge (GB); John Gonzalez-Carvajal, Haslemere (GB); Marc Brown, Watford (GB); and Rob Turner, Portsmouth (GB)
Assigned to ENDOMAGNETICS LTD., Cambridge (GB)
Filed by Endomagnetics Ltd., Cambridge (GB)
Filed on Mar. 10, 2014, as Appl. No. 14/202,178.
Claims priority of provisional application 61/775,780, filed on Mar. 11, 2013.
Prior Publication US 2014/0314679 A1, Oct. 23, 2014
Int. Cl. A61B 5/055 (2006.01); A61K 49/18 (2006.01); A61K 41/00 (2006.01); A61N 2/00 (2006.01)
CPC A61K 49/1806 (2013.01) [A61K 41/0052 (2013.01); A61K 49/1863 (2013.01); A61N 2/002 (2013.01)] 14 Claims
 
1. A hypoosmotic suspension for medical injection comprising:
about 13 mg/mL to about 200 mg/mL of superparamagnetic particles; and
an osmolyte selected from either about 0.01% w/v to about 0.6% w/v of an inorganic salt or about 0.5% w/v to about 1.5% w/v of a glycol
wherein the hypoosmotic suspension has an osmolality of about 80 mOsm/kg to about 160 mOsm/kg.