US 9,808,506 B2
Compositions comprising semaphorins for the treatment of cancer and methods of selection thereof
Gera Neufeld, Haifa (IL); Boaz Kigel, Kiryat-tivon (IL); Ofra Kessler, Haifa (IL); and Asya Varshavsky, Haifa (IL)
Assigned to RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES, Haifa (IL)
Filed by RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES, Haifa (IL)
Filed on Sep. 8, 2015, as Appl. No. 14/847,025.
Application 13/941,574 is a division of application No. 13/313,063, filed on Dec. 7, 2011, granted, now 8,513,194, issued on Aug. 20, 2013.
Application 13/313,063 is a division of application No. 12/738,634, granted, now 8,088,735, issued on Jan. 3, 2012, previously published as PCT/IL2008/001307, filed on Oct. 2, 2008.
Application 14/847,025 is a continuation in part of application No. 13/941,574, filed on Jul. 15, 2013, granted, now 9,155,781.
Claims priority of provisional application 61/071,560, filed on May 6, 2008.
Claims priority of provisional application 61/071,053, filed on Apr. 10, 2008.
Claims priority of provisional application 61/006,496, filed on Jan. 16, 2008.
Claims priority of provisional application 60/960,910, filed on Oct. 19, 2007.
Prior Publication US 2016/0263182 A1, Sep. 15, 2016
Int. Cl. A61K 36/16 (2006.01); A61K 38/17 (2006.01); C07K 14/435 (2006.01); A61K 47/48 (2006.01); G01N 33/574 (2006.01)
CPC A61K 38/177 (2013.01) [A61K 38/1709 (2013.01); G01N 33/57484 (2013.01); G01N 2333/71 (2013.01); G01N 2800/52 (2013.01)] 15 Claims
 
1. A method of treating cancer in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a composition comprising an amino acid sequence at least 89% identical to the sequence set forth in SEQ ID NO: 32, thereby treating the cancer.