US 9,808,493 B2
Exopolysaccharide-producing bacteria, and uses thereof for protecting heart health
Catherine Stanton, County Cork (IE); Paul Ross, County Cork (IE); Gerald F. Fitzgerald, Cork (IE); Noel Caplice, County Cork (IE); and Fergus Shanahan, Cork (IE)
Assigned to University College Cork—National University of Ireland, Cork, Cork (IE); and Agriculture and Food Development Authority (TEAGASC), Co Carlow (IE)
Appl. No. 14/425,236
Filed by University College Cork—National University of Ireland, Cork, Cork (IE); and Agriculture and Food Development Authority (TEAGASC), County Carlow (IE)
PCT Filed Sep. 2, 2013, PCT No. PCT/EP2013/068119
§ 371(c)(1), (2) Date Mar. 2, 2015,
PCT Pub. No. WO2014/033307, PCT Pub. Date Mar. 6, 2014.
Claims priority of application No. 12182693 (EP), filed on Aug. 31, 2012.
Prior Publication US 2015/0329923 A1, Nov. 19, 2015
Int. Cl. A23C 9/123 (2006.01); C08B 37/00 (2006.01); C12N 1/20 (2006.01); A61K 35/747 (2015.01); C12P 19/04 (2006.01); C12R 1/225 (2006.01); A23L 33/135 (2016.01)
CPC A61K 35/747 (2013.01) [A23C 9/1234 (2013.01); A23L 33/135 (2016.08); C08B 37/006 (2013.01); C12N 1/20 (2013.01); C12P 19/04 (2013.01); C12R 1/225 (2013.01); A23C 2220/206 (2013.01); A23Y 2220/00 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method of reducing total serum cholesterol levels in a mammal, comprising a step of administering to the mammal an isolated Lactobacillus mucosae (DPC6426) strain deposited with the National Collection of Industrial and Marine Bacteria Limited (NCIMB) on 27 Jul. 2012 under NCIMB Deposit Accession No. 42015, or a variant thereof, wherein the isolated Lactobacillus mucosae (DPC6426) strain and variant thereof express an exopolysaccharide comprising monosaccharide residues xylose, fucose, mannose, glucose, galactose, N-acetylglucosamine, and N-acetylmannosamine.