US 9,808,467 B2
Methods for treating GI tract disorders
Cyril De Colle, Campbell, CA (US); and Pankaj Pasricha, Ellicott City, MD (US)
Assigned to NEUROGASTRX, INC., Campbell, CA (US)
Filed by Neurogastrx, Inc., Campbell, CA (US)
Filed on Aug. 7, 2015, as Appl. No. 14/820,885.
Application 14/820,885 is a continuation of application No. 14/555,455, filed on Nov. 26, 2014, granted, now 9,132,134.
Application 14/555,455 is a continuation of application No. PCT/US2013/076733, filed on Dec. 19, 2013.
Claims priority of provisional application 61/745,734, filed on Dec. 24, 2012.
Prior Publication US 2015/0342958 A1, Dec. 3, 2015
Int. Cl. A61K 31/197 (2006.01); A61K 31/198 (2006.01); A61K 31/5415 (2006.01); A61K 45/06 (2006.01); C07D 417/06 (2006.01)
CPC A61K 31/5415 (2013.01) [A61K 31/197 (2013.01); A61K 31/198 (2013.01); A61K 45/06 (2013.01); C07D 417/06 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method of treating an enteric nervous system disorder in a human subject in need thereof, comprising administering to the subject an effective dose of a compound of formula III

OG Complex Work Unit Drawing
or a pharmaceutically acceptable salt, solvate, or metabolite thereof, wherein the administering occurs for over 5 days.