US 9,808,434 B2
Compound for treating cancer and diabetes
Samuel Rahbar, Beverly Hills, CA (US); James L. Figarola, West Covina, CA (US); Christopher Lincoln, La Canada, CA (US); David Horne, Altadena, CA (US); Rachael Mooney, Duarte, CA (US); Monika Polewski, Duarte, CA (US); George Somlo, Seal Beach, CA (US); Lixin Yang, Arcadia, CA (US); Sanjay Awasthi, San Marino, CA (US); Sharad Singhal, Duarte, CA (US); and Jyotasana Singhal, Duarte, CA (US)
Assigned to CITY OF HOPE, Duarte, CA (US)
Filed by CITY OF HOPE, Duarte, CA (US)
Filed on Jun. 4, 2016, as Appl. No. 15/173,628.
Application 15/173,628 is a continuation in part of application No. 13/953,013, filed on Jul. 29, 2013.
Application 13/953,013 is a continuation of application No. PCT/US2012/023034, filed on Jan. 27, 2012.
Claims priority of provisional application 61/436,958, filed on Jan. 27, 2011.
Prior Publication US 2016/0354327 A1, Dec. 8, 2016
Int. Cl. A61K 31/17 (2006.01); A61K 45/06 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01); C07D 229/00 (2006.01); A61K 31/495 (2006.01)
CPC A61K 31/17 (2013.01) [A61K 31/4745 (2013.01); A61K 31/495 (2013.01); A61K 31/513 (2013.01); A61K 45/06 (2013.01); C07D 229/00 (2013.01)] 16 Claims
OG exemplary drawing
1. A method of treating a cancer in a subject in need thereof, comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of 1,3-bis (3,5-dichlorophenyl) urea (COH-SR4), a salt thereof, or stereoisomers thereof, wherein the cancer is selected from the group consisting of melanoma, and lung cancer.