US 9,808,407 B2
Porous silica particle, method for producing the same, and cosmetic containing the same
Naoyuki Enomoto, Kitakyushu (JP); Satoshi Watanabe, Kitakyushu (JP); and Yasutaka Miyoshi, Kitakyushu (JP)
Assigned to JGC CATALYSTS AND CHEMICALS LTD., Kawasaki-Shi, Kanagawa (JP)
Appl. No. 15/318,431
Filed by JGC Catalysts and Chemicals Ltd., Kawasaki-Shi, Kanagawa (JP)
PCT Filed Jun. 30, 2015, PCT No. PCT/JP2015/068872
§ 371(c)(1), (2) Date Dec. 13, 2016,
PCT Pub. No. WO2016/002797, PCT Pub. Date Jan. 7, 2016.
Claims priority of application No. 2014-134192 (JP), filed on Jun. 30, 2014.
Prior Publication US 2017/0135920 A1, May 18, 2017
Int. Cl. A61K 8/25 (2006.01); A61K 8/29 (2006.01); A61K 8/19 (2006.01); A61Q 1/12 (2006.01); A61K 8/02 (2006.01); A61Q 1/02 (2006.01)
CPC A61K 8/25 (2013.01) [A61K 8/0279 (2013.01); A61K 8/19 (2013.01); A61K 8/29 (2013.01); A61Q 1/02 (2013.01); A61Q 1/12 (2013.01); A61K 2800/412 (2013.01)] 8 Claims
 
1. A porous silica particle comprising:
silica microparticles comprising:
a mean micro-particle diameter (d2) of more than 100 nm and 1000 nm or less,
a sphericity of 0.85 to 1, and
a CV-value of less than 15%,
wherein the porous silica particle comprises:
a mean particle diameter (d1) of 0.5 to 25 μm,
a specific surface area obtained by the BET method of 5 to 60 m2/cm3, and
a pore volume of 0.35 to 2.0 ml/g,
wherein in a pore size distribution (X axis: pore diameter, Y axis: value obtained by differentiating pore volume by pore diameter) of the porous silica particle, the minimum pore diameter (D0) is in the range of 25 to 500 nm, the maximum pore diameter (D100) is in the range of 300 to 8000 nm, and the ratio of the maximum pore diameter (D100) to the minimum pore diameter (D0), (D100/D0), is in the range of 4 to 320.