US 9,808,204 B2
Noninvasive physiological analysis using excitation-sensor modules and related devices and methods
Steven Francis LeBoeuf, Raleigh, NC (US); Jesse Berkley Tucker, Knightdale, NC (US); and Michael Edward Aumer, Raleigh, NC (US)
Assigned to Valencell, Inc., Raleigh, NC (US)
Filed by Steven Francis LeBoeuf, Raleigh, NC (US); Jesse Berkley Tucker, Knightdale, NC (US); and Michael Edward Aumer, Raleigh, NC (US)
Filed on Aug. 3, 2012, as Appl. No. 13/566,269.
Application 13/566,269 is a continuation of application No. 12/256,793, filed on Oct. 23, 2008, granted, now 8,251,903.
Claims priority of provisional application 61/000,181, filed on Oct. 25, 2007.
Prior Publication US 2012/0296184 A1, Nov. 22, 2012
Int. Cl. A61B 5/021 (2006.01); A61B 5/1455 (2006.01); A61B 5/00 (2006.01); A61B 5/026 (2006.01); A61B 5/0295 (2006.01); A61B 5/02 (2006.01); A61B 5/024 (2006.01); A61B 6/00 (2006.01)
CPC A61B 5/721 (2013.01) [A61B 5/0261 (2013.01); A61B 5/0295 (2013.01); A61B 5/02116 (2013.01); A61B 5/02141 (2013.01); A61B 5/1455 (2013.01); A61B 5/14552 (2013.01); A61B 5/6815 (2013.01); A61B 5/6838 (2013.01); A61B 5/021 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/046 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A method of assessing blood pressure in an organism, the method comprising:
directing light at one or more regions of the organism via at least two optical emitters, wherein at least one optical emitter generates light at a first wavelength, wherein at least one other optical emitter generates light at a second wavelength shorter than the first wavelength, and wherein the second wavelength is in the range of blue-UV;
detecting, via an optical detector, light at the first and second wavelengths scattered from the organism and generating, via the optical detector, a first electrical signal associated with the first wavelength and a second electrical signal associated with the second wavelength; and
processing, via at least one processor, the first and second electrical signals, wherein the processing comprises:
filtering each of the first and second electrical signals with respect to skin motion noise to generate a first extracted signal associated with the first wavelength and a second extracted signal associated with the second wavelength that is distinct from the first extracted signal, wherein the first extracted signal comprises information about blood flow through a blood vessel of the organism, and wherein the second extracted signal comprises information about size of the blood vessel; and
comparing the first extracted signal and the second extracted signal, responsive to generation of each by the filtering with respect to the skin motion noise, in context of a physiological model to assess the blood pressure of the organism, wherein the comparing comprises:
calculating the blood pressure of the organism based on an area of the blood vessel and based on a volumetric flow rate of blood therein, wherein the area is based on the size of the blood vessel and a change in the size thereof indicated by the second extracted signal, and wherein the volumetric flow rate is indicated by the first extracted signal.