US 9,808,191 B2
Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods
Ning Yang, New York, NY (US); and Rajiv Shah, Rancho Palos Verdes, CA (US)
Assigned to MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed by MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed on Mar. 8, 2017, as Appl. No. 15/453,119.
Application 15/453,119 is a continuation of application No. 14/933,372, filed on Nov. 5, 2015, granted, now 9,625,414.
Application 14/933,372 is a continuation of application No. 13/778,514, filed on Feb. 27, 2013, granted, now 9,213,010, issued on Dec. 15, 2015.
Claims priority of provisional application 61/755,811, filed on Jan. 23, 2013.
Claims priority of provisional application 61/754,475, filed on Jan. 18, 2013.
Claims priority of provisional application 61/754,479, filed on Jan. 18, 2013.
Claims priority of provisional application 61/754,483, filed on Jan. 18, 2013.
Claims priority of provisional application 61/754,485, filed on Jan. 18, 2013.
Claims priority of provisional application 61/657,517, filed on Jun. 8, 2012.
Prior Publication US 2017/0176381 A1, Jun. 22, 2017
Int. Cl. A61B 5/1495 (2006.01); G01N 27/416 (2006.01); G01N 27/02 (2006.01); G01N 33/66 (2006.01); G01N 33/96 (2006.01); A61B 5/145 (2006.01); A61B 5/053 (2006.01); A61B 5/00 (2006.01)
CPC A61B 5/1495 (2013.01) [A61B 5/0537 (2013.01); A61B 5/14503 (2013.01); A61B 5/14532 (2013.01); A61B 5/7221 (2013.01); A61B 5/746 (2013.01); G01N 27/026 (2013.01); G01N 27/4163 (2013.01); G01N 33/66 (2013.01); G01N 33/96 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A method of calibrating a sensor during a period of sensor transition, the method comprising:
defining an electrochemical impedance spectroscopy (EIS)-based sensor status vector (V) for each one of a plurality of sensor current (Isig)-blood glucose (BG) pairs;
defining an Isig buffer to store Isig values of said plurality of Isig-BG pairs;
defining an BG buffer to store BG values of said plurality of Isig-BG pairs;
monitoring the status vectors for the plurality of Isig-BG pairs over time;
detecting when there is a difference between a first status vector for a first Isig-BG pair and a subsequent status vector for a subsequent Isig-BG pair;
if a magnitude of said difference is smaller than a predetermined threshold, calibrating said sensor based on values of said Isig-BG pairs from a first set of Isig and BG buffers; and
if the magnitude of said difference is larger than a predetermined threshold, calibrating said sensor based on values of said Isig-BG pairs from a second set of Isig and BG buffers, wherein said second set of Isig and BG buffers contains at least the values of Isig and BG from said subsequent Isig-BG pair.