US 9,808,189 B2
Concentration-measurement device and concentration-measurement method
Yasuaki Koyama, Kawasaki (JP); Takeo Ozaki, Hamamatsu (JP); and Susumu Suzuki, Hamamatsu (JP)
Assigned to St. Marianna University School of Medicine, Kawasaki-shi, Kanagawa (JP); and HAMAMATSU PHOTONICS K.K., Hamamatsu-shi, Shizuoka (JP)
Appl. No. 14/112,702
Filed by Yasuaki Koyama, Kawasaki (JP); Takeo Ozaki, Hamamatsu (JP); and Susumu Suzuki, Hamamatsu (JP)
PCT Filed Apr. 6, 2012, PCT No. PCT/JP2012/059581
§ 371(c)(1), (2), (4) Date Nov. 4, 2013,
PCT Pub. No. WO2012/144356, PCT Pub. Date Oct. 26, 2012.
Claims priority of application No. 2011-095318 (JP), filed on Apr. 21, 2011.
Prior Publication US 2014/0058233 A1, Feb. 27, 2014
Int. Cl. A61B 5/1455 (2006.01); A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 5/026 (2006.01); A61H 31/00 (2006.01); A61B 5/0295 (2006.01)
CPC A61B 5/14551 (2013.01) [A61B 5/0261 (2013.01); A61B 5/1455 (2013.01); A61B 5/14535 (2013.01); A61B 5/14546 (2013.01); A61B 5/14553 (2013.01); A61B 5/6814 (2013.01); A61B 5/72 (2013.01); A61B 5/742 (2013.01); A61B 5/0295 (2013.01); A61H 31/005 (2013.01); A61H 2201/5092 (2013.01); A61H 2230/201 (2013.01); A61H 2230/208 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A concentration measurement apparatus measuring a temporal relative change amount of at least one of total hemoglobin concentration, oxygenated hemoglobin concentration, and deoxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, comprising:
a light source that makes measurement light having at least a first wavelength λ1 and a second wavelength λ2 incident on the head;
a light detector that detects the measurement light that has propagated through the interior of the head and generating a first detection signal corresponding to the first wavelength λ1 and a second detection signal corresponding to the second wavelength λ2 in accordance with an intensity of the measurement light; and
a processor electrically connected to the light detector and programmed to determine, based on the first detection signal and the second detection signal, the temporal relative change amount of at least one of the total hethoglobin concentration (ΔcHb), the oxygenated hemoglobin concentration (ΔO2Hb), and the deoxygenated hemoglobin concentration (ΔHHb),
wherein the processor is programmed to perform a filtering process that removes frequency components less than a predetermined frequency of not more than 1.66 Hz to extract information on the concentration change due to chest compression, and calculate information related to a variation frequency of the relative change amount corresponding to a current frequency of chest compression, and
wherein a calculation cycle of the relative change amount is not more than 0.2 seconds.