US 9,808,171 B2
Utilization of electrode spatial arrangements for characterizing cardiac conduction conditions
Ram K. Balachandran, Maple Grove, MN (US); and D. Curtis Deno, Andover, MN (US)
Assigned to St. Jude Medical, Atrial Fibrillation Division, Inc., St. Paul, MN (US)
Appl. No. 14/782,134
Filed by St. Jude Medical, Atrial Fibrillation Division, Inc., St. Paul, MN (US)
PCT Filed May 7, 2014, PCT No. PCT/US2014/037160
§ 371(c)(1), (2) Date Oct. 2, 2015,
PCT Pub. No. WO2014/182822, PCT Pub. Date Nov. 13, 2014.
Claims priority of provisional application 61/855,058, filed on May 7, 2013.
Prior Publication US 2016/0045133 A1, Feb. 18, 2016
Int. Cl. A61B 5/04 (2006.01); A61B 5/042 (2006.01); A61B 5/0452 (2006.01); A61B 5/06 (2006.01); A61B 18/14 (2006.01); A61B 5/00 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); A61B 34/20 (2016.01)
CPC A61B 5/0422 (2013.01) [A61B 5/0452 (2013.01); A61B 5/061 (2013.01); A61B 5/7203 (2013.01); A61B 18/1492 (2013.01); A61B 34/20 (2016.02); A61B 5/062 (2013.01); A61B 5/7239 (2013.01); A61B 2017/00039 (2013.01); A61B 2017/00044 (2013.01); A61B 2017/00053 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00839 (2013.01); A61B 2034/2051 (2016.02); A61B 2034/2053 (2016.02); A61B 2218/002 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system for determining electrophysiological data, comprising:
an electronic control unit configured to:
receive electrogram data for a set of electrodes,
compose a clique of at least three neighboring electrodes from the set of electrodes, wherein the electrogram data comprises a plurality of bipole signals taken between the at least three neighboring electrodes in the clique;
receive position and orientation information for the set of electrodes from a mapping system;
derive an E-field from the plurality of bipole signals of the clique, wherein bipole signals taken between the at least three neighboring electrodes in the clique overdetermine the E-field;
determine catheter orientation independent information of a tissue based on the electrogram data and position and orientation information from the set of electrodes, wherein the catheter orientation independent information comprises a local tangent E-field and an orthogonal unit vector in the direction along which a wavefront is propagating (a); and
output the orientation independent information to a user or process.