US 9,808,168 B2
Method and system for non-invasive measurement of cardiac parameters
Daniel A. Goor, Tel Aviv (IL); Efim Frinerman, Bat Yam (IL); Evgeny Granov, Ra'anana (IL); and Igor Granov, Raanana (IL)
Assigned to New N.I. Medical (2011) LTD., Petah Tikva (IL)
Filed by New N.I. Medical (2011) LTD., Petah Tikva (IL)
Filed on Nov. 17, 2014, as Appl. No. 14/543,114.
Application 14/543,114 is a continuation of application No. 12/439,985, granted, now 8,911,379, previously published as PCT/IL2007/001088, filed on Sep. 4, 2007.
Claims priority of provisional application 60/842,035, filed on Sep. 5, 2006.
Prior Publication US 2015/0073250 A1, Mar. 12, 2015
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/02 (2006.01); A61B 5/04 (2006.01); A61B 5/029 (2006.01); A61B 5/053 (2006.01); A61B 5/0205 (2006.01); A61B 5/021 (2006.01); A61B 5/0408 (2006.01); A61B 5/0432 (2006.01); A61B 5/044 (2006.01); A61B 5/0295 (2006.01); A61B 5/024 (2006.01)
CPC A61B 5/04012 (2013.01) [A61B 5/021 (2013.01); A61B 5/0205 (2013.01); A61B 5/029 (2013.01); A61B 5/02028 (2013.01); A61B 5/02035 (2013.01); A61B 5/0295 (2013.01); A61B 5/044 (2013.01); A61B 5/0408 (2013.01); A61B 5/04011 (2013.01); A61B 5/0432 (2013.01); A61B 5/053 (2013.01); A61B 5/024 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An impedance measurement system for assessment of at least one cardiac parameter of an individual, the impedance measurement system comprising:
a measurement unit comprising an electrodes arrangement comprising a first and second electrode sets, the first electrode set being configured and operable to attach to one arm at a first lateral side of the individual's body and the second electrode set being configured and operable to attach to one leg at a second lateral side of the individual's body, said electrodes arrangement being configured and operable to apply an electrical field to the body through one of the first and second electrode sets and to obtain an electrical output through the other of the first and second electrode sets, said electrical output comprising measured data indicative of both systolic impedance change, ΔR, and velocity of a systolic impedance change, δR/δt, of the individual during a cardiac cycle; and
a control unit comprising:
a data input utility configured and operable for receiving input data indicative of at least one condition of the individual, said at least one condition being indicative of whether the individual is sustained by an acute heart failure (AHF), and for receiving said measured data;
a processor programmed for analyzing said input data indicative of said at least one condition of the individual, and upon identifying that said input data is indicative of that the individual is sustained by AHF, selecting the data of the velocity of systolic impedance change for calculating the at least one cardiac parameter of the individual, and
upon identifying that said input data is indicative of that the individual is not sustained by AHF, either selecting the data of systolic impedance change for calculating the at least one cardiac parameter, or analyzing additional input data indicative of at least one other predetermined condition of the individual in order to determine whether to use the systolic impedance change data or the velocity of systolic impedance change data, said at least one other condition comprising value of at least one of a total peripheral resistance (TPR) and a cardiac index (CI); and
a data output utility configured and operable for generating an output indicative of the calculation result.