US 9,808,160 B2
Systems and methods for monitoring and analyzing cardiovascular states
Jan K. Berkow, Allison Park, PA (US); and Anne M. Brumfield, Cranberry Township, PA (US)
Assigned to Intelomed, Inc., Wexford, PA (US)
Filed by Intelomed, Inc., Wexford, PA (US)
Filed on Aug. 12, 2014, as Appl. No. 14/457,946.
Claims priority of provisional application 61/865,114, filed on Aug. 12, 2013.
Prior Publication US 2015/0045633 A1, Feb. 12, 2015
Int. Cl. A61B 5/05 (2006.01); A61B 5/0205 (2006.01); A61B 3/16 (2006.01); A61B 5/021 (2006.01); A61B 5/024 (2006.01); G06F 19/00 (2011.01); A61B 5/00 (2006.01); A61B 5/053 (2006.01); A61B 5/0452 (2006.01); A61B 5/08 (2006.01); A61B 5/16 (2006.01)
CPC A61B 5/0205 (2013.01) [A61B 3/16 (2013.01); A61B 5/02108 (2013.01); A61B 5/02416 (2013.01); A61B 5/7257 (2013.01); A61B 5/7275 (2013.01); A61B 5/746 (2013.01); G06F 19/34 (2013.01); G06F 19/3481 (2013.01); A61B 5/002 (2013.01); A61B 5/0022 (2013.01); A61B 5/0452 (2013.01); A61B 5/053 (2013.01); A61B 5/08 (2013.01); A61B 5/165 (2013.01); A61B 5/4848 (2013.01); A61B 5/7278 (2013.01); A61B 5/7282 (2013.01); A61B 5/7405 (2013.01); A61B 5/7475 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A system for determining a cardiovascular state of a patient in a stress condition, the system comprising:
at least one sensor configured to received one or more signals from the patient;
a computing device in data communication with the at least one sensor; a non-transitory, computer-readable storage medium in operable communication with the computing device;
an input device in operable communication with the computing device; and
an output device in operable communication with the computing device;
wherein the computer-readable storage medium contains one or more programming instructions that, when executed, cause the computing device to:
receive at least one signal in the time domain from the at least one sensor, wherein the at least one signal in the time domain is a pulse wave measurement of the patient;
determine at least one metric in the time domain from the at least one signal in the time domain;
determine at least one metric in the frequency domain from the at least one signal in the time domain;
derive one or more sets of parameters using the at least one metric in the time domain and the at least one metric in the frequency domain, a set of parameters being associated with a particular cardiovascular state;
evaluate temporal variations of the parameters within the one or more sets of parameters; and
determine the cardiovascular state of the patient from a combination of the temporal variations of parameters in a set of parameters and information from at least one database of cardiovascular states that are associated with the sets of parameters.