US 9,808,031 B2
Systems and methods to estimate nutritional needs of human and other patients
Michael A Horning, San Francisco, CA (US); and George A Brooks, Seattle, WA (US)
Assigned to RUN THEM SWEET LLC, San Francisco, CA (US)
Filed by Run Them Sweet, LLC, San Francisco, CA (US)
Filed on May 28, 2013, as Appl. No. 13/903,929.
Claims priority of provisional application 61/795,819, filed on Oct. 25, 2012.
Prior Publication US 2014/0120206 A1, May 1, 2014
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/49 (2006.01); A23L 33/00 (2016.01); G01N 33/58 (2006.01); A61K 31/047 (2006.01); A61K 31/155 (2006.01); A61K 31/19 (2006.01); A61K 31/7004 (2006.01); A61K 47/02 (2006.01); A61K 31/22 (2006.01); G01N 33/66 (2006.01); A61K 31/221 (2006.01); A61K 31/225 (2006.01); A23L 33/10 (2016.01); A61K 9/00 (2006.01); A61K 31/198 (2006.01)
CPC A23L 33/30 (2016.08) [A23L 33/10 (2016.08); A61K 9/0029 (2013.01); A61K 31/047 (2013.01); A61K 31/155 (2013.01); A61K 31/19 (2013.01); A61K 31/198 (2013.01); A61K 31/22 (2013.01); A61K 31/221 (2013.01); A61K 31/225 (2013.01); A61K 31/7004 (2013.01); A61K 47/02 (2013.01); G01N 33/58 (2013.01); G01N 33/66 (2013.01); A23V 2002/00 (2013.01); Y10T 436/144444 (2015.01)] 84 Claims
 
1. A method for estimating a fractional gluconeogenesis of a patient, the method comprising:
analyzing one or more glucose or glucose derivatives, which have been previously labeled by a label administered to the patient, from a blood sample from the patient;
running a mass spectrometric reading in order to analyze the one or more glucose derivatives in order to obtain a value or set of values for gluconeogenesis and a value or set of values for gluconeogenesis plus glycogenolysis, from the mass spectrometric reading; and
using the values or sets of values from the mass spectrometric reading to estimate fractional gluconeogenesis;
wherein the value or set of values for gluconeogenesis and the value or set of values for gluconeogenesis plus glycogenolysis all come from a same mass spectrometric reading.