Patent Terms Extended
                           Less Than 35 U.S.C.   156

        Certificates extending the terms of the following patents were
                           issued on July 15, 1998.
   
U.S. Patent No. 4,254,129; Granted March 3, 1981, to
Albert A. Carr et al.; Owner of Record: Merrell Pharmaceuticals; Title:
Piperidine Derivatives; Classification: 514/317; Product Trade Name:
ALLEGRA ; Original Expiration Date: April 10, 1999; Term Extended: 679
days.

U.S. Patent No. 4,260,769; Granted April 7, 1981, to Valentino J. Stella
et al.; Owner of Record: Merck & Co., Inc.; Title:
5,5-Diphenylhydantoins; Classification: 548/112; Product Trade Name:
CEREBYX  (fosphenytoin sodium); Original Expiration Date: April 7,
1998; Term Extended: Five years.

U.S. Patent No. 4,639,436; Granted January 27, 1987, to Bodo Junge et
al.; Owner of Record: Bayer AG; Title: Antidiabetic
3,4,5-Trihydroxypiperidines; Classification: 514/24; Product Trade Name:
GLYSET  (Miglitol); Original Expiration Date: January 27, 2004; Term
Extended: Five years.

U.S. Patent No. 4,670,444; Granted June 2, 1987, to Klaus Grohe et al.;
Owner of Record: Bayer Aktiengesellschaft; Title:
7-Amino-l-Cyclopropyl-4-Oxo-1,4-Dihydro-Quinoline-and
Naphthyridine-3-Carboxylic Acids and Antibacterial Agents Containing
These Compounds; Classification: 514/300; Product Trade Name: BAYTRIL  
(enrofloxacin); Original Expiration Date: December 9, 2003; Term
Extended: Three years.

U.S. Patent No. 4,681,893; Granted July 21, 1987, to Bruce D. Roth;
Owner of Record: Wamer-Lambert Company; Title: Trans-6-[2-(3- or
4-Carboxamido-Substituted Pyrrol-1-Yl)Alkyl]-4-Hydroxypyran-2-One
Inhibitors of Cholesterol Synthesis; Classification: 514/422; Product
Trade Name: LIPITOR  (atorvastatin calcium); Original Expiration Date:
May 30, 2006; Term Extended: 1,213 days.

U.S. Patent No. 4,689,339; Granted August 25, 1987, to Arto J.
Karjalainen et al.; Owner of Record: Orion-Yhtyma Oy; Title:
4-Dihydroinden-2-YL-,4-Tetrahydronaphth-2-YL-, And
4-Dihydrobenzofuran-2-Ylimidazoles, Useful to Block   2-Andrenergic
Receptors; Classification: 514/396; Product Trade Name: ANTISEDAN  
(atipamezole hydrochloride); Original Expiration Date: November 21,
2005; Term Extended: 1,719 days.

U.S. Patent No. 4,861,584; Granted August 29, 1989, to Thomas W. Powell,
Jr. et al.; Owner of Record: United Catalysts, Inc.; Title: Allergen
Absorbent and Blocking Aerosol Composition; Classification: 424/79;
Product Trade Name: IVY BLOCK  (bentoquatam); Original Expiration
Date: August 29, 2006; Term Extended: 1,458 days.

U.S. Patent No. 4,902,683; Granted February 20, 1990, to Amin et al.;
Owner of Record: Pharmacia & Upjohn Company; Title: Crystalline
Cephalosporin Hydrohalide Salts; Classification: 514/206; Product Trade
Name: EXCENEL  Sterile Suspension; Original Expiration Date: February
20, 2007; Term Extended: 460 days.


           Certificates extending the terms of the following patents
                      were issued on September 15, 1997:

U.S. Patent No. 4,406,899; Granted September 27, 1983, to Shimpei
Aburaki et al.; Owner of Record: Bristol-Myers Company; Title:
Cephalosporins; Classification: 424/246; Product Trade Name: MAXIPIME  
(cefepime hydrochloride); Original Expiration Date: March 4, 2002; Term
Extended: Five years.

U.S. Patent No. 4,544,664; Granted October 1, 1985, to Arto J.
Karjalainen et al.; Owner of Record: Orion-Yhtyma Oy; Title:
Antihypertensive Substituted Imidazole Derivatives; Classification:
514/396; Product Trade Name: DOMITOR  (medetomidine hydrochloride);
Original Expiration Date: February 11, 2001; Term Extended: Three years.

U.S. Patent No. 4,686,214; Granted August 11, 1987, to John J.
Boltralik; Owner of Record: Alcon Laboratories, Inc.; Title:
Anti-Inflammatory Compounds for Ophthalmic Use; Classification: 514/179;
Product Trade Name: VEXOL  (rimexolone); Original Expiration Date:
October 30, 2005; Term Extended: 996 days; Expiration Date of Extension:
July 22, 2008.

U.S. Patent No. 5,045,302; Granted September 3, 1991, to James D. Kelly
et al.; Owner of Record: Amersham International plc.; Title: Ligands and
Cationic Complexes Thereof with Technetium-99M; Classification: 424/1.1;
Product Trade Name: MYOVIEW  (technetium tc99m tetrofosmin); Original
Expiration Date: October 6, 2008; Term Extended: 491 days; Expiration
Date of Extension: February 9, 2010.