US 7,468,836 B2
Cytological imaging systems and methods
Garrick L. Maenle, Columbus, Ohio (US); William J. Knox, West Jefferson, Ohio (US); and David Zahniser, Wellesley, Mass. (US)
Assigned to CYTYC Corporation, Marlborough, Mass. (US)
Filed on Sep. 25, 2007, as Appl. No. 11/861,234.
Application 11/861234 is a continuation of application No. 10/008379, filed on Nov. 05, 2001, granted, now 7,369,304.
Application 10/008379 is a continuation in part of application No. 09/430198, filed on Oct. 29, 1999, granted, now 7,006,674.
Application 09/430198 is a continuation in part of application No. 09/430116, filed on Oct. 29, 1999, granted, now 6,348,325.
Claims priority of provisional application 60/245971, filed on Nov. 03, 2000.
Prior Publication US 2008/0018994 A1, Jan. 24, 2008
Int. Cl. G02B 21/00 (2006.01)
U.S. Cl. 359—383  [359/368; 250/201.3; 382/128] 23 Claims
OG exemplary drawing
 
1. An automatic focusing method for an optical system, comprising:
performing an initial coarse focus action along a focal axis at a scan position corresponding to a point on a surface of a slide;
respectively performing a plurality of subsequent fine focus actions along a plurality of focal axes at a plurality of scan positions corresponding to different points on the slide surface, wherein the performance of each of the fine focus actions comprises determining a fine in-focus coordinate along the respective focal axis, determining an area of fine focus jurisdiction surrounding the respective point, and correlating the fine in-focus coordinate to the respective fine focus jurisdiction area; and
determining if another scan position corresponds to a point within at least one previously determined fine focus jurisdiction area.