US 7,468,421 B2
Depilatories and agents for external use
Atsushi Ohuchi, Tochigi (Japan); Akemi Kobayashi, Tochigi (Japan); and Akira Hachiya, Tochigi (Japan)
Assigned to Kao Corporation, Tokyo (Japan)
Filed on Jan. 03, 2005, as Appl. No. 11/26,090.
Application 11/026090 is a continuation of application No. 10/110226, granted, now 6,884,772, previously published as PCT/JP00/07218, filed on Oct. 18, 2000.
Claims priority of application No. 11-299305 (JP), filed on Oct. 21, 1999.
Prior Publication US 2005/0112079 A1, May 26, 2005
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/00 (2006.01)
U.S. Cl. 530—326  [514/2; 514/19; 424/70.1] 8 Claims
 
1. A method of depilation, comprising:
transdermally administering or topically intracutaneously applying a depilatory-containing composition containing an active ingredient selected from the group consisting of endothelin and an endothelin agonist to a subject to achieve the removal of hair from said subject, wherein the depilatory-containing composition contains at least one additive selected from the group consisting of a keratolytic agent, a salt of a keratolytic agent, thioglycolic acid, a salt of thioglycolic acid, purified water, ethanol, an oiliness substance, a humectant, a thickener, a preservative, an emulsifier, an ultraviolet absorber, a color, a fragrance, and an emulsion stabilizer.