| US 7,468,384 B2 | ||
| Microbicidal composition | ||
| Richard Levy, Valbonne (France); Megan Anne Diehl, Line Lexington, Pa. (US); Dolores Ann Shaw, Collegeville, Pa. (US); and Eileen Fleck Warwick, Lansdale, Pa. (US) | ||
| Assigned to Rohm and Haas Company, Philadelphia, Pa. (US) | ||
| Filed on Nov. 02, 2005, as Appl. No. 11/265,654. | ||
| Claims priority of provisional application 60/628326, filed on Nov. 16, 2004. | ||
| Prior Publication US 2006/0106024 A1, May 18, 2006 | ||
| Int. Cl. A01N 43/80 (2006.01); A61K 31/425 (2006.01) | ||
| U.S. Cl. 514—373 | 2 Claims |
| 1. A microbicidal composition comprising:
(a) 1,2-benzisothiazolin-3-one; and
(b) at least one microbicide selected from the group consisting of benzalkonium chloride, benzethonium chloride, benzyl alcohol,
caprylyl glycol, chlorphenesin, diazolidinyl urea, ethylparaben, imidazolidinyl urea, methylparaben, phenoxyethanol, linoleamidopropyl
PG-dimonium chloride phosphate, cocamidopropyl PG-dimonium chloride phosphate, propylparaben, Cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane
chloride, dehydroacetic acid or its salts, benzoic acid or its salts, and sodium hydroxymethylglycinate
wherein a weight ratio of 1,2-benzisothiazolin-3-one to benzalkonium chloride is from 1:0.025 to 1:40, a weight ratio of 1,2-benzisothiazolin-3-one
to benzethonium chloride is from 1:0.13 to 1:3, a weight ratio of 1,2-benzisothiazolin-3-one to benzyl alcohol is from 1:0.4
to 1:35, a weight ratio of 1,2-benzisothiazolin-3-one to caprylyl glycol is from 1:0.7 to 1:67, a weight ratio of 1,2-benzisothiazolin-3-one
to chlorphenesin is from 1:20 to 1:50, a weight ratio of 1,2-benzisothiazolin-3-one to diazolidinyl urea is from 1:1 to 1:100,
a weight ratio of 1,2-benzisothiazolin-3-one to ethylparaben is from 1:13 to 1:400, a weight ratio of 1,2-benzisothiazolin-3-one
to imidazolidinyl urea is from 1:20 to 1:30, a weight ratio of 1,2-benzisothiazolin-3-one to methylparaben is from 1:3 to
1:240, a weight ratio of 1,2-benzisothiazolin-3-one to phenoxyethanol is from 1:2.5 to 1:800, a weight ratio of 1,2-benzisothiazolin-3-one
to linoleamidopropyl PG-dimonium chloride phosphate is from 1:0.5 to 1:800, a weight ratio of 1,2-benzisothiazolin-3-one to
cocamidopropyl PG-dimonium chloride phosphate is from 1:1.3 to 1:800, a weight ratio of 1,2-benzisothiazolin-3-one to propylparaben
is from 1:13 to 1:320, a weight ratio of 1,2-benzisothiazolin-3-one to Cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane
chloride is from 1:4 to 1:240, a weight ratio of 1,2-benzisothiazolin-3-one to dehydroacetic acid or its salts is from 1:0.4
to 1:5, a weight ratio of 1,2-benzisothiazolin-3-one to benzoic acid or its salts is from 1:5 to 1:2000, and a weight ratio
of 1,2-benzisothiazolin-3-one to sodium hydroxymethylglycinate is from 1:27 to 1:100.
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