US 7,468,365 B2
Lactam compound
James Edmund Audia, Zionsville, Ind. (US); Benjamin Alan Diseroad, Martinsville, Ind. (US); Varghese John, San Francisco, Calif. (US); Lee H. Latimer, Oakland, Calif. (US); Jeffrey Scott Nissen, Indianapolis, Ind. (US); Gregory Alan Stephenson, Fishers, Ind. (US); Eugene D. Thorsett, Half Moon Bay, Calif. (US); and Jay S. Tung, Belmont, Calif. (US)
Assigned to Eli Lilly and Company, Indianapolis, Ind. (US); and Elan, South San Francisco, Calif. (US)
Filed on Jan. 11, 2006, as Appl. No. 11/329,859.
Application 11/329859 is a continuation in part of application No. 10/416771, abandoned, previously published as PCT/US01/27799, filed on Nov. 05, 2001.
Application 11/329859 is a continuation in part of application No. 11/329859.
Application 11/329859 is a continuation in part of application No. 10/415057, abandoned, previously published as PCT/US01/27796, filed on Nov. 02, 2001.
Application 11/329859 is a continuation in part of application No. 11/329859.
Application 11/329859 is a continuation in part of application No. 10/415548, abandoned, previously published as PCT/US01/27795, filed on Nov. 02, 2001.
Claims priority of provisional application 60/249552, filed on Nov. 17, 2000.
Claims priority of provisional application 60/249655, filed on Nov. 17, 2000.
Claims priority of provisional application 60/249656, filed on Nov. 17, 2000.
Prior Publication US 2007/0299053 A1, Dec. 27, 2007
Int. Cl. C07D 223/16 (2006.01); A61K 31/55 (2006.01); A61P 25/28 (2006.01)
U.S. Cl. 514—212.07  [540/523] 15 Claims
 
1. (N)-((S)-2-Hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one or the dihydrate thereof.