| US 7,468,160 B2 | ||
| Devices and methods for performing array based assays | ||
| Allen C. Thompson, Sunnyvale, Calif. (US); George P. Tsai, San Jose, Calif. (US); and Russell Alan Parker, San Jose, Calif. (US) | ||
| Assigned to Agilent Technologies, Inc., Santa Clara, Calif. (US) | ||
| Filed on Dec. 05, 2003, as Appl. No. 10/729,606. | ||
| Prior Publication US 2005/0123931 A1, Jun. 09, 2005 | ||
| Int. Cl. G01N 21/00 (2006.01); G01N 15/06 (2006.01); B01L 3/00 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01) | ||
| U.S. Cl. 422—56 [422/68.1; 422/102; 422/58; 422/61; 435/287.9; 435/288.3; 435/286.5] | 11 Claims |
| 1. An assay device comprising:
(a) a base;
(b) a cover;
(c) a clamping member for holding said cover to said base, wherein said clamping member comprises:
(i) a bridge comprising at least two extending arm portions that terminate in feet portions and a bore; and
(ii) a rotatable screw disposed within said bridge; and
(d) a flexure or spring element that interacts with said clamping member, wherein said assay device is configured such that
upon actuation said clamping member applies a force to the cover and base in a manner sufficient to produce a substantially
uniform distance between an array assembly and backing element along the entire length of the cover and base when said array
assembly and backing element are present in said device, wherein said array assay device comprises at least one flexure.
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