US 7,465,381 B2
Electrokinetic molecular separation in nanoscale fluidic channels
Gabriel P. Lopez, Albuquerque, N. Mex. (US); Steven R. J. Brueck, Albuquerque, N. Mex. (US); Linnea K. Ista, Albuquerque, N. Mex. (US); Anthony L. Garcia, Albuquerque, N. Mex. (US); Dimiter N. Petsev, Albuquerque, N. Mex. (US); Paul Bisong, Albuquerque, N. Mex. (US); and Michael J. O'Brien, Albuquerque, N. Mex. (US)
Assigned to STC.UNM, Albuquerque, N. Mex. (US)
Filed on Oct. 04, 2004, as Appl. No. 10/958,113.
Claims priority of provisional application 60/589200, filed on Jul. 19, 2004.
Claims priority of provisional application 60/538862, filed on Jan. 22, 2004.
Prior Publication US 2006/0169587 A1, Aug. 03, 2006
Int. Cl. G01N 27/447 (2006.01)
U.S. Cl. 204—451  [204/450; 977/924; 977/962] 22 Claims
OG exemplary drawing
 
1. A method for separation of molecules in at least one nanochannel comprising:
providing at least one nanochannel having charged nanochannel walls;
providing an electrolyte solution to the at least one nanochannel so that an electrical double layer forms near the charged nanochannel walls;
introducing a mixture of at least two different types of molecules into at least one nanochannel;
allowing electroosmosis through at least one nanochannel to transport at least one of the at least two molecule types within the nanochannel and to separate at least two different types of molecules within the nanochannel.