| US 7,462,165 B2 | ||
| Medical device with sponge coating for controlled drug release | ||
| Ni Ding, Plymouth, Minn. (US); and W. Scott Andrus, Eden Prairie, Minn. (US) | ||
| Assigned to Boston Scientific Scimed, Inc., Maple Grove, Minn. (US) | ||
| Filed on Feb. 07, 2002, as Appl. No. 10/71,400. | ||
| Application 10/071400 is a division of application No. 09/060071, filed on Apr. 14, 1998, granted, now 6,364,856. | ||
| Prior Publication US 2002/0082552 A1, Jun. 27, 2002 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. A61M 29/00 (2006.01) | ||
| U.S. Cl. 604—103.02 | 7 Claims |
| 1. A catheter for delivering a biologically active material to a desired location of a body lumen of a patient comprising
an expandable portion which is insertable or implantable into a body lumen, wherein the expandable portion is expandable in
response to inflation pressure to fill the cross-section of the lumen and engage the tissue of the lumen and wherein the expandable
portion comprises:
a) a balloon having an outer surface;
b) a membrane having a plurality of pores therein wherein the membrane comprises an outer surface and an inner surface, wherein
the membrane is disposed about the balloon;
c) a reservoir space disposed between the outer surface of the balloon, and the inner surface of the membrane and wherein
the reservoir space is connected to a reservoir lumen for filling the reservoir space with the biologically active material;
and
d) a biostable sponge coating disposed upon the outer surface of the membrane wherein the sponge coating is exposed to the
body lumen when the catheter is inserted or implanted into the body lumen and, wherein the sponge coating comprises a non-hydrogel
polymer having a plurality of voids and wherein the sponge coating is in fluid communication with the reservoir space such
that the biologically active material when present in the reservoir space can pass through the pores of the membrane and enter
the voids.
|