US 11,836,924 B2
Assisted or automatic generating of a digital representation of an annulus structure of a valve of a human internal organ
Julian Praceus, Munich (DE); and Aleksei Vasilev, Munich (DE)
Assigned to LARALAB GmbH, Munich (DE)
Appl. No. 17/279,410
Filed by LARALAB GmbH, Munich (DE)
PCT Filed Sep. 25, 2019, PCT No. PCT/EP2019/075919
§ 371(c)(1), (2) Date Mar. 24, 2021,
PCT Pub. No. WO2020/064866, PCT Pub. Date Apr. 2, 2020.
Claims priority of application No. 18196601 (EP), filed on Sep. 25, 2018.
Prior Publication US 2022/0012887 A1, Jan. 13, 2022
Int. Cl. G06K 9/00 (2022.01); G06T 7/11 (2017.01)
CPC G06T 7/11 (2017.01) [G06T 2207/10076 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/20096 (2013.01); G06T 2207/20101 (2013.01); G06T 2207/30048 (2013.01); G06T 2207/30052 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method for generating a digital representation of an annulus structure of a heart valve from a segmented digital representation of a human heart, comprising:
a) providing an input segmented digital representation of a plurality of portions of a human heart comprising an annulus structure of a heart valve, wherein the input segmented digital representation provides labels for the portions of the digital representation, which labels indicate specific properties of the respective portion and/or belonging of the respective portion to a specific anatomic structure, wherein the digital representation comprises, and/or is based on, multi-slice computed tomography image data for three spatial dimensions for each of at least one effective time point;
b) automatically determining, for at least a first effective time point, based on the labels of the provided input segmented digital representation, a candidate plane, and/or a candidate orientation vector together with a candidate center point, arranged with respect to the input segmented digital representation for the first effective time point;
d) automatically determining a plurality of candidate points for the annulus structure at the first effective time point based on the input segmented digital representation, wherein automatically determining a plurality of candidate points includes determining a plurality of selecting cross-sections with respect to the input segmented digital representation at the first effective time point, wherein the selecting cross-sections are arranged essentially orthogonally to the candidate plane and/or essentially comprise the candidate center point and the candidate orientation vector;
e) automatically generating a candidate spline interpolation for the first effective time point using the determined candidate points as support points;
f) automatically adapting the candidate spline interpolation for the first effective time point based on the input segmented digital representation; and
g) generating a digital representation of the annulus structure at the first effective time point based on the adapted candidate spline interpolation,
wherein
the annulus structure to be determined belongs to a first valve of the human heart;
a candidate center point for a second valve of the human heart is automatically determined; and
at least one of the plurality of selecting cross sections is automatically determined as a plane which intersects the automatically determined candidate center point of the second valve.