| US 7,456,952 B2 | ||
| System for real-time fluorescent determination of trace elements | ||
| Dwight Sherod Walker, Durham, N.C. (US) | ||
| Assigned to SmithKline Beecham Corporation, Philadelphia, Pa. (US) | ||
| Filed on Sep. 13, 2006, as Appl. No. 11/531,469. | ||
| Application 11/531469 is a continuation of application No. 10/363294, granted, now 7,277,168, previously published as PCT/US01/26892, filed on Aug. 29, 2001. | ||
| Claims priority of provisional application 60/228673, filed on Aug. 29, 2000. | ||
| Prior Publication US 2007/0091308 A1, Apr. 26, 2007 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. G01J 3/30 (2006.01) | ||
| U.S. Cl. 356—317 [250/458.1] | 14 Claims |
| 1. A system for use in in-situ analysis of pharmaceutical samples, said system comprising:
means for holding a plurality of said samples, wherein said samples are present in the form of a powder formulation;
means for moving said plurality of samples along a sample path;
means for generating a plurality of incident radiation pulses of different wavelength;
means for illuminating at least a respective one of said samples with at least a respective one of said radiation pulses during
said movement of said samples, said radiation pulse having a suitable range of radiation wavelengths capable of inducing a
fluorescent response;
means for detecting a first resultant fluorescence emitted from each of said samples;
first control means in communication with said moving means and said incident radiation generating means for synchronizing
said means for illuminating each of said samples with said moving means.
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