US 7,456,322 B2
Process for preparing 1,3-dibromoacetone, 1-3-dichloroacetone and epichlorohydrin
Clark S. Davis, Oakley, Calif. (US)
Assigned to Dow Global Technologies Inc., Midland, Mich. (US)
Appl. No. 10/593,397
PCT Filed May 17, 2005, PCT No. PCT/US2005/017193
§ 371(c)(1), (2), (4) Date Oct. 04, 2006,
PCT Pub. No. WO2005/115954, PCT Pub. Date Dec. 08, 2005.
Prior Publication US 2008/0249324 A1, Oct. 09, 2008
Int. Cl. C07C 45/00 (2006.01); C07D 301/02 (2006.01)
U.S. Cl. 568—388  [568/393; 568/411; 549/518] 39 Claims
 
1. A process for preparing 1,3-dibromoacetone which comprises:
(a) reacting acetone with bromine to make a mixture of brominated acetone derivatives and byproduct hydrogen bromide;
(b) equilibrating the mixture of brominated acetone derivatives to produce 1,3-dibromoacetone as the major product;
(c) crystallizing the 1,3-dibromoacetone in the mixture of brominated acetone derivatives mother liquor; and
(d) isolating the 1,3-dibromoacetone from the mixture of brominated acetone derivatives.