P is phenyl, whereby the phenyl ring is substituted on position 3 or disubstituted on positions 2 and 5;

R¹ is attached to P via a carbon atom on ring P and is selected from the group consisting of hydrogen, hydroxy, halo, nitro, C_1-6alkylhalo, OC_1-6alkylhalo, C_1-6alkyl, OC_1-6alkyl, C_2-6alkenyl, OC_2-6alkenyl, C_2-6alkynyl, OC_2-6alkynyl, C_0-6alkylC_3-6cycloalkyl, OC_0-6alkylC_3-6cycloalkyl, C_0-6alkylaryl, OC_0-6alkylaryl, CHO, (CO)R⁵, O(CO)R⁵, O(CO)OR⁵, O(CN)OR⁵, C_1-6alkylOR⁵, OC_2-6alkylOR⁵, C_1-6alkyl(CO)R⁵, OC_1-6alkyl(CO)R⁵, C_0-6alkylCO₂R⁵, OC_1-6alkylCO₂R⁵, C_0-6alkylcyano, OC_2-6alkylcyano, C_0-6alkylNR⁵R⁶, OC_2-6alkylNR⁵R⁶, C_1-6alkyl(CO)NR⁵R⁶, OC_1-6alkyl(CO)NR⁵R⁶, C_0-6alkylNR⁵(CO)R⁶, OC_2-6alkylNR⁵(CO)R⁶, C_0-6alkylNR⁵(CO)NR⁵R⁶, C_0-6alkylSR⁵, OC_2-6alkylSR⁵, C_0-6alkyl(SO)R⁵, OC_2-6alkyl(SO)R⁵, C_0-6alkylSO₂R⁵, OC_2-6alkylSO₂R⁵, C_0-6alkyl(SO₂)NR⁵R⁶, OC_2-6alkyl(SO₂)NR⁵R⁶, C_0-6alkylNR⁵(SO₂)R⁶, OC_2-6alkylNR⁵(SO₂)R⁶, C_0-6alkylNR⁵(SO₂)NR⁵R⁶, OC_2-6alkylNR⁵(SO₂)NR⁵R⁶, (CO)NR⁵R⁶, O(CO)NR⁵R⁶, NR⁵OR⁶, C_0-6alkylNR⁵(CO)OR⁶, OC_2-6alkylNR⁵(CO)OR⁶, SO₃R⁵ and a 5- or 6-membered ring containing one or more atoms independently selected from the group consisting of C, N, O and S;

M¹ is a bond;

X¹ is C;

X² is selected from the group consisting of N, and O;

X³ is selected from the group consisting of N, and O;

where the ring containing X¹, X² and X³ forms an, isoxazole, chloro-isoxazole or a methyl-isoxazole;

R is selected from the group consisting of hydrogen, C_0-3alkyl, halo, C_0-3alkylOR⁵, C_0-3alkylNR⁵R⁶, C_0-3alkyl(CO)OR⁵ and C_0-3alkylaryl;

M² is selected from a group consisting of C_1-3alkyl, and C_2-3alkynyl;

R³ is selected from a group consisting of hydrogen, hydroxy, C_0-6alkylcyano, oxo, ═NR⁵, ═NOR⁵, C_1-4alkylhalo, halo, C_1-4alkyl, O(CO)C_1-4alkyl, C_1-4alkyl(SO)C_0-4alkyl, C_1-4alkyl(SO₂)C_0-4alkyl, (SO)C_0-4alkyl, (SO₂)C_0-4alkyl, OC_1-4alkyl, C_1-4alkylOR⁵ and C_0-4alkylNR⁵R⁶;

X⁴ is wherein the bond between M² and X⁴ is a single bond;

Q is triazolyl, wherein any substitutable nitrogen atom in the ring is substituted with R⁴ on such nitrogen atom and any suitable carbon atom is optionally substituted with R⁴; and

R⁴ is selected from the group consisting of C_0-6alkylcyano, ═NC_1-4alkyl, ═NOR⁵, C_1-4alkylhalo, halo, C_1-6alkyl, OC_1-4alkyl, C_2-4alkenyl, C_0-2alkylC_3-6cycloalkyl, C_0-6alkylaryl, C_0-6alkylheteroaryl, OC_0-6alkylaryl, OC_0-6alkylheteroaryl, NC_0-6alkylaryl, NC_0-6alkylheteroaryl, C_0-6alkylOaryl, C_0-6alkylOheteroaryl, C_0-6akylNaryl, C_0-6alkylNheteroaryl, OC_0-6alkylOaryl, OC_0-6alkylOheteroaryl, OC_0-6alkylNaryl, OC_0-6alkylNheteroaryl, NC_0-6alkylOaryl, NC_0-6alkylOheteroaryl, NC_0-6alkylNaryl, NC_0-6alkylNheteroaryl, O(CO)C_1-4alkyl, C_0-4alkyl(CO)OC_1-4alkyl, C_1-4alkyl(S)C_0-4alkyl, C_1-4alkyl(SO)C_0-4alkyl, C_1-4alkyl(SO₂)C_0-4alkyl, (SO)C_0-4alkyl, (SO₂)C_0-4alkyl, C_1-4alkylOR⁵, C_0-4alkylN(C_1-4alkyl)₂ and a 3- or 6-membered non-aromatic ring containing one or more atoms independently selected from C, N, O and S, which ring may optionally be fused with a 5-membered ring containing one or more atoms independently selected from the group consisting of C, N and O and wherein said ring and said fused ring may be substituted by one or two A; or

ii) selected from the group consisting of tetrahydrotriazolopyridyl, tetrahydrotriazolopyrimidinyl, and pyridonyl; and

R⁴ is selected from the group consisting of hydrogen, hydroxy, C_0-6alkylcyano, ═NR⁵, ═NOR⁵, C_1-4alkylhalo, halo, C_1-6alkyl, OC_1-4alkyl, OC_0-6alkylaryl, O(CO)C_1-4alkyl, C_0-4alkyl(S)C_0-4alkyl, C_1-4alkyl(SO)C_0-4alkyl, C_1-4alkyl(SO₂)C_0-4alkyl, (SO)C_0-4alkyl, (SO₂)C_0-4alkyl, C_1-4alkylOR⁵, C_0-4alkylNR⁵R⁶ and a 5- or 6-membered ring containing one or more atoms independently selected from C, N, O and S, which ring may optionally be fused with a 5 or 6 membered ring containing one or more atoms independently selected from the group consisting of C, N and O and wherein said ring and said fused ring may be substituted by one or two A;

R⁵ and R⁶ are independently selected from the group consisting of hydrogen and C_1-6alkyl;

wherein any C_1-6alkyl defined under R¹, R² and R⁴ may be substituted by one or more A;

A is selected from the group consisting of hydrogen, hydroxy, halo, nitro, oxo, C_0-6alkylcyano, C_0-4alkylC_3-6cycloalkyl, C_1-6alkyl, C_1-6alkylhalo, OC_1-6alkylhalo, C_2-6alkenyl, C_0-3alkylaryl, C_0-6alkylOR⁵, OC_2-6alkylOR⁵, C_1-6alkylSR⁵, OC_2-6alkylSR⁵, (CO)R⁵, O(CO)R⁵, OC_2-6alkylcyano, OC_1-6alkylCO₂R⁵, O(CO)OR⁵, OC_1-6alkyl(CO)R⁵, C_1-6alkyl(CO)R⁵, NR⁵OR⁶, OC_2-6alkylNR⁵R⁶, C_0-6alkyl(CO)NR⁵R⁶, OC_1-6alkyl(CO)NR⁵R⁶, OC_2-6alkylNR⁵(CO)R⁶, C_0-6alkylNR⁵(CO)R⁶, C_0-6alkylNR⁵(CO)NR⁵R⁶, O(CO)NR⁵R⁶, C_0-6alkyl(SO₂)NR⁵R⁶, OC_2-6alkyl(SO₂)NR⁵R⁶, C_0-6alkylNR⁵(SO₂)R⁶, OC_2-6alkylNR⁵(SO₂)R⁶, SO₃R⁵, C_1-6alkylNR⁵(SO₂)NR⁵R⁶, OC_2-6alkyl(SO₂)R⁵, C_0-6alkyl(SO₂)R⁵, C_0-6alkyl(SO)R⁵, OC_2-6alkyl(SO)R⁵ and a 5-membered ring containing one or more atoms independently selected from the group consisting of C, N, O and S;

m1 is selected from 0, 1, 2, 3 and 4;

m2 is selected from 0, 1, 2 and 3;

n is selected from 0, 1 and 2; and

t is 0 or 1, and a salt thereof.