| US 7,455,977 B2 | ||
| Methods of determining the level of human TBP-II with anti-TBP-II antibody | ||
| David Wallach, Rehovot (Israel); Jacek Bigda, Gdansk (Poland); Igor Beletsky, Pushino (Russian Federation); Igor Mett, Rehovot (Israel); and Hartmut Engelmann, Munich (Germany) | ||
| Assigned to Yeda Research and Development Co. Ltd., Rehovot (Israel) | ||
| Filed on Aug. 04, 2003, as Appl. No. 10/632,929. | ||
| Application 10/632929 is a division of application No. 09/800908, filed on Mar. 08, 2001, granted, now 6,602,993. | ||
| Application 09/800908 is a division of application No. 08/477347, filed on Jun. 07, 1995, granted, now 6,232,446. | ||
| Application 08/477347 is a continuation in part of application No. 07/930443, filed on Aug. 19, 1992. | ||
| Application 07/930443 is a continuation of application No. 07/524263, filed on May 16, 1990, abandoned. | ||
| Application 08/477347 is a continuation in part of application No. 08/450972, filed on May 25, 1995, abandoned. | ||
| Application 08/450972 is a continuation of application No. 08/115685, filed on Sep. 03, 1993, abandoned. | ||
| Claims priority of application No. 90339 (IL), filed on May 18, 1989; application No. 91229 (IL), filed on Aug. 06, 1989; application No. 94039 (IL), filed on Apr. 06, 1990; application No. 103051 (IL), filed on Sep. 03, 1992; and application No. 106271 (IL), filed on Jul. 08, 1993. | ||
| Prior Publication US 2004/0161858 A1, Aug. 19, 2004 | ||
| Int. Cl. G01N 33/53 (2006.01) | ||
| U.S. Cl. 435—7.1 | 2 Claims |
| 1. An immunoassay method for the human TNF Binding Protein TBP-II (residues 27-214 of SEQ ID NO:3) in body fluids, comprising:
obtaining a sample of body fluid from a subject;
incubating the sample with an antibody to human TBP-II which specifically recognizes and binds said protein; and
determining the level of human TBP-II in the sample by the level of antibody bound to human TBP-II.
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