US 7,451,761 B2
Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
Anthony James Hickey, Chapel Hill, N.C. (US); Timothy Crowder, Durham, N.C. (US); Jeffrey Alan Warden, Raleigh, N.C. (US); Keith Arthur Johnson, Durham, N.C. (US); Mark Ennis Ketner, Apex, N.C. (US); Jay Kinsley Fording, Matthews, N.C. (US); Michael Duane Garten, Charlotte, N.C. (US); William Myles Riley, Richmond, Va. (US); Sean Derek Anderson, Richmond, Va. (US); Bruce Seymour Ferris, Richmond, Va. (US); and Paul Gilbert Rockwell, Chesterfield, Va. (US)
Assigned to Oriel Therapeutics, Inc., Durham, N.C. (US)
Filed on Oct. 21, 2004, as Appl. No. 10/970,154.
Claims priority of provisional application 60/514671, filed on Oct. 27, 2003.
Prior Publication US 2005/0103337 A1, May 19, 2005
Int. Cl. A61M 15/00 (2006.01); A61M 16/00 (2006.01); B05D 7/14 (2006.01); B65D 83/06 (2006.01)
U.S. Cl. 128—203.21  [128/203.15] 52 Claims
OG exemplary drawing
 
31. A method of dispensing dry powder from an inhaler, comprising:
extending a mouthpiece of an inhaler outward to automatically index a blister on a blister package into a dispensing position;
vibrating the indexed blister; and
retracting the mouthpiece inward to open the indexed blister, wherein the retracting step comprises automatically advancing a cutting blade across a portion of a projecting ceiling of the indexed blister in the inhaler responsive to the retraction.