US 11,815,459 B2
Optical detection system, blood cell analyzer, and platelet detection method
Qiushi Yi, Shenzhen (CN); Dongsheng Wang, Shenzhen (CN); and Yong Dai, Shenzhen (CN)
Assigned to Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen (CN)
Filed by Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen (CN)
Filed on Mar. 28, 2022, as Appl. No. 17/706,268.
Application 17/706,268 is a continuation of application No. 17/081,757, filed on Oct. 27, 2020, granted, now 11,307,145.
Application 17/081,757 is a continuation of application No. PCT/CN2019/084509, filed on Apr. 26, 2019.
Claims priority of application No. 201810405048.9 (CN), filed on Apr. 28, 2018.
Prior Publication US 2022/0268703 A1, Aug. 25, 2022
Int. Cl. G01N 21/47 (2006.01); G01N 21/64 (2006.01); G01N 33/487 (2006.01)
CPC G01N 21/6486 (2013.01) [G01N 21/47 (2013.01); G01N 33/487 (2013.01)] 16 Claims
OG exemplary drawing
 
1. An optical detection system, comprising an optical subsystem, a flow chamber and a first detector;
the optical subsystem comprising a laser, a front optical assembly and a rear optical assembly, and the front optical assembly comprising an optical isolator, wherein:
the laser is configured to emit a laser beam;
the front optical assembly is configured to perform front optical treatment on the laser beam, and the laser beam subjected to the front optical treatment is converged at a plurality of platelet particles in the flow chamber in a first direction, and scattered light is thus generated;
the rear optical assembly is disposed downstream of the flow chamber along a propagation direction of the laser beam, and is configured to perform rear optical treatment on the scattered light, so that the scattered light subjected to the rear optical treatment enters the first detector for light intensity detection, to obtain a detection result corresponding to the plurality of platelet particles; and
the optical isolator is configured to isolate reflected light from the laser, wherein the reflected light is generated when the laser beam passes through the flow chamber, wherein
the optical isolator comprises a beam splitter prism and a polarization conversion element which are adhesively connected with each other; the beam splitter prism is configured to reflect an S-polarization component of an incident laser beam and transmit a P-polarization component of the incident laser beam; and the polarization conversion element is configured to change a polarization state of the P-polarization component transmitted through the beam splitter prism so that the P-polarization component is changed from linearly polarized light into circularly polarized light, as well as to change a polarization state of the circularly polarized light after reflection into S-polarized light so that the S-polarized light is reflected by the beam splitter prism; or
the optical isolator comprises a polarization analyzer and a polarization conversion element which are adhesively connected with each other; the polarization analyzer is configured to allow only a P-polarization component of the laser beam to pass through; and the polarization conversion element is configured to change a polarization state of the P-polarization component passing through the polarization analyzer so that the P-polarization component is changed from linearly polarized light into circularly polarized light, as well as to change a polarization state of reflected light of the circularly polarized light into S-polarized light so that the S-polarized light is isolated by the polarization analyzer.